The effect of experimentally induced carbon dioxide pneumoperitoneum on intra-abdominal and intra-esophageal pH

Results: In the CO2 group, IA and IE pH values significantly decreased (P < 0.05). IA pH values decreased in the CO 2 group when compared to the control and O 2 groups (P < 0.05). There was not a significant difference in IE pH between the CO2 group and the other groups. Conclusion: CO2 insufflation decreased IA pH values. Decreased pH values obtained with continuous recordings of the esophagus may have been related to increases in intra-abdominal pressure, rather than the metabolic effects of CO2 pneumoperitoneum.

[1]  T. Soyer,et al.  In vitro sensitivity of mouse esophagus to agonists in different pH medium values. , 2007, Journal of pediatric surgery.

[2]  M. Talamini,et al.  Abdominal insufflation with CO2 causes peritoneal acidosis independent of systemic pH , 2005, Journal of Gastrointestinal Surgery.

[3]  J. Kuebler,et al.  Acidification during carbon dioxide pneumoperitoneum is restricted to the gas-exposed peritoneal surface: effects of pressure, gas flow, and additional intraperitoneal fluids. , 2006, Journal of laparoendoscopic & advanced surgical techniques. Part A.

[4]  A. Alver,et al.  The acute alterations in biochemistry, morphology, and contractility of rat-isolated terminal ileum via increased intra-abdominal pressure. , 2006, Pharmacological research.

[5]  M. Kusano,et al.  Helium gas pneumoperitoneum can improve the recovery of gastrointestinal motility after a laparoscopic operation , 2005, Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy.

[6]  J. Hunter,et al.  Carbon dioxide pneumoperitoneum induces fetal acidosis in a pregnant ewe model , 1995, Surgical Endoscopy.

[7]  Y. Ku,et al.  Comparison of intestinal transit recovery between laparoscopic and open surgery using a rat model , 2003, Surgical Endoscopy And Other Interventional Techniques.

[8]  W. J. Russell,et al.  Metabolic and immunologic consequences of laparoscopy with helium or carbon dioxide insufflation: A randomized clinical study , 2001, ANZ journal of surgery.

[9]  C. Herfarth,et al.  Effect of pressure and gas type on intraabdominal, subcutaneous, and blood pH in laparoscopy , 2000, Surgical Endoscopy.

[10]  C. Malbert,et al.  Metabolic Acidosis and Respiratory Acidosis Impair Gastro-Pyloric Motility in Anesthetized Pigs , 2000, Anesthesia and analgesia.

[11]  D. Chassard,et al.  The Effect of Increase in End-Tidal Carbon Dioxide on Lower Esophageal Sphincter Tone , 1996, Anesthesia and analgesia.

[12]  K. Schulze-Delrieu,et al.  Depression of mechanical and electrical activity in muscle strips of opossum stomach and esophagus by acidosis. , 1982, Gastroenterology.