Low hematocrit during cardiopulmonary bypass is associated with increased risk of perioperative stroke in cardiac surgery.

[1]  S. McCluskey,et al.  The independent association of massive blood loss with mortality in cardiac surgery. , 2005 .

[2]  V. Rao,et al.  Hemodilution during cardiopulmonary bypass is an independent risk factor for acute renal failure in adult cardiac surgery. , 2005, The Journal of thoracic and cardiovascular surgery.

[3]  S. McCluskey,et al.  The independent association of massive blood loss with mortality in cardiac surgery , 2004, Transfusion.

[4]  Laura P Coombs,et al.  The Society of Thoracic Surgeons: 30-day operative mortality and morbidity risk models. , 2003, The Annals of thoracic surgery.

[5]  R. Habib,et al.  Adverse effects of low hematocrit during cardiopulmonary bypass in the adult: should current practice be changed? , 2003, The Journal of thoracic and cardiovascular surgery.

[6]  Volkmar Falk,et al.  Stroke after cardiac surgery: a risk factor analysis of 16,184 consecutive adult patients. , 2003, The Annals of thoracic surgery.

[7]  R. Jonas.  Optimal hematocrit for adult cardiopulmonary bypass. , 2001, Journal of cardiothoracic and vascular anesthesia.

[8]  H. Schäfers,et al.  Effects of Hematocrit on Cerebral Microcirculation and Tissue Oxygenation During Deep Hypothermic Bypass , 2001, Circulation.

[9]  J. van der Linden,et al.  Postoperative stroke in cardiac surgery is related to the location and extent of atherosclerotic disease in the ascending aorta. , 2001, Journal of the American College of Cardiology.

[10]  C. Peniston,et al.  Stroke during coronary bypass surgery: principal role of cerebral macroemboli. , 2001, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[11]  R. Groom,et al.  Lowest hematocrit on bypass and adverse outcomes associated with coronary artery bypass grafting. Northern New England Cardiovascular Disease Study Group. , 2001, The Annals of thoracic surgery.

[12]  T. Mizuno,et al.  Thickened intima of the aortic arch is a risk factor for stroke with coronary artery bypass grafting. , 2000, The Annals of thoracic surgery.

[13]  M. Newman,et al.  Intraoperative physiologic variables and outcome in cardiac surgery: Part II. Neurologic outcome. , 2000, The Annals of thoracic surgery.

[14]  N. Kouchoukos,et al.  Atherosclerosis of the ascending aorta is an independent predictor of long-term neurologic events and mortality. , 1999, Journal of the American College of Cardiology.

[15]  T. Orszulak,et al.  Minimum hematocrit at differing cardiopulmonary bypass temperatures in dogs. , 1998, Circulation.

[16]  M L Lesser,et al.  Impact of minimum hematocrit during cardiopulmonary bypass on mortality in patients undergoing coronary artery surgery. , 1997, Circulation.

[17]  F. Dexter,et al.  Effect of haemoglobin concentration on brain oxygenation in focal stroke: a mathematical modelling study. , 1997, British journal of anaesthesia.

[18]  T. Miura,et al.  Higher hematocrit improves cerebral outcome after deep hypothermic circulatory arrest. , 1996, The Journal of thoracic and cardiovascular surgery.

[19]  B. Hindman,et al.  Cerebral blood flow and oxygen delivery during hypoxemia and hemodilution: role of arterial oxygen content. , 1994, The American journal of physiology.

[20]  R. Tibshirani,et al.  An Introduction to the Bootstrap , 1995 .

[21]  T. Treasure,et al.  The Impact of Microemboli During Cardiopulmonary Bypass on Neuropsychological Functioning , 1994, Stroke.

[22]  M. A. Bell,et al.  Brain microemboli during cardiac surgery or aortography , 1990, Annals of neurology.

[23]  J. French,et al.  An analysis of factors predisposing to neurological injury in patients undergoing coronary bypass operations. , 1989, The Quarterly journal of medicine.

[24]  C. Jenkins,et al.  Neuropsychological dysfunction following elective cardiac operation: I. Early assessment , 1982 .

[25]  S. Hashimoto,et al.  Stroke in Coronary Bypass Surgery , 1982, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[26]  R. D. Alley,et al.  The society of thoracic surgeons. , 1976, The Annals of thoracic surgery.

[27]  J M Stengle,et al.  Open-heart surgery and the demand for blood. , 1973, JAMA.

[28]  B. Reichart,et al.  Cardiopulmonary bypass and cerebral injury in adults. , 2001, Shock.

[29]  A. du Plessis,et al.  Effects of oncotic pressure and hematocrit on outcome after hypothermic circulatory arrest. , 1998, The Annals of thoracic surgery.

[30]  R. Tibshirani,et al.  Estimates of bias , 1993 .