Association of CDK4 and CCND1 mRNA overexpression in laryngeal squamous cell carcinomas occurs without CDK4 amplification

[1]  H. Hermeking,et al.  Evidence for a cancer-specific switch at the CDK4 promoter with loss of control by both USF and c-Myc , 2004, Oncogene.

[2]  Y. Dong,et al.  Cyclin D1‐CDK4 complex, a possible critical factor for cell proliferation and prognosis in laryngeal squamous cell carcinomas , 2001, International journal of cancer.

[3]  E. Campo,et al.  Disregulation of p16MTS1/CDK4I protein and mRNA expression is associated with gene alterations in squamous‐cell carcinoma of the larynx , 1999, International journal of cancer.

[4]  C. Conti,et al.  Coordinated changes in cell cycle machinery occur during keratinocyte terminal differentiation , 1999, Oncogene.

[5]  J. Decaprio,et al.  Role of CDK4 and p16INK4A in interleukin-6-mediated growth of multiple myeloma , 1997, Leukemia.

[6]  M. Tsai,et al.  Regulation of androgen-dependent prostatic cancer cell growth: androgen regulation of CDK2, CDK4, and CKI p16 genes. , 1997, Cancer research.

[7]  E. Campo,et al.  p21WAF1/Cip1 expression is associated with cell differentiation but not with p53 mutations in squamous cell carcinomas of the larynx , 1997, The Journal of pathology.

[8]  E. Campo,et al.  p16MTS1/CDK4I mutations and concomitant loss of heterozygosity at 9p21-23 are frequent events in squamous cell carcinoma of the larynx , 1997, Oncogene.

[9]  P. Guldberg,et al.  Complete scanning of the CDK4 gene by denaturing gradient gel electrophoresis: A novel missense mutation but low overall frequency of mutations in sporadic metastatic malignant melanoma , 1997, International journal of cancer.

[10]  A. Bellacosa,et al.  Altered expression of cyclin D1 and CDK4 genes in ovarian carcinomas , 1997, International journal of cancer.

[11]  K. G. Coleman,et al.  Identification of CDK4 Sequences Involved in Cyclin D1 and p16 Binding* , 1997, The Journal of Biological Chemistry.

[12]  J. Bartek,et al.  Mutual requirement of CDK4 and Myc in malignant transformation: evidence for cyclin D1/CDK4 and p16INK4A as upstream regulators of Myc , 1997, Oncogene.

[13]  E. Hovig,et al.  Involvement of the pRb/p16/cdk4/cyclin D1 pathway in the tumorigenesis of sporadic malignant melanomas. , 1996, British Journal of Cancer.

[14]  T. Sekiya,et al.  Homozygous deletion of the MTS1/p16 and MTS2/p15 genes and amplification of the CDK4 gene in glioma. , 1995, Oncogene.

[15]  M. Serrano,et al.  A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma , 1995, Science.

[16]  T. Hunter,et al.  Cyclins and cancer II: Cyclin D and CDK inhibitors come of age , 1994, Cell.

[17]  C. James,et al.  CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines. , 1994, Cancer research.

[18]  F. Bosch,et al.  PRAD-1/cyclin D1 gene amplification correlates with messenger RNA overexpression and tumor progression in human laryngeal carcinomas. , 1994, Cancer research.

[19]  P. Meltzer,et al.  Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2. , 1994, Cancer research.

[20]  S. Shurtleff,et al.  D-type cyclin-dependent kinase activity in mammalian cells , 1994, Molecular and cellular biology.

[21]  A. Look,et al.  Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas. , 1993, Cancer research.

[22]  R. Weinberg,et al.  Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[23]  J. Ferlay,et al.  Estimates of the worldwide incidence of eighteen major cancers in 1985 , 1993, International journal of cancer.

[24]  Steven K. Hanks,et al.  Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins , 1992, Cell.

[25]  T. Hunter,et al.  Cyclins and cancer , 1991, Cell.

[26]  A. Robles,et al.  Synchronized proliferation induced by 12-O-tetradecanoylphorbol-13-acetate treatment of mouse skin: an in vivo model for cell cycle regulation. , 1998, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[27]  A. Sober,et al.  Novel mutations in the p16/CDKN2A binding region of the cyclin-dependent kinase-4 gene. , 1998, Cancer research.

[28]  N. Hayward,et al.  Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma , 1996, Nature Genetics.