Association of CDK4 and CCND1 mRNA overexpression in laryngeal squamous cell carcinomas occurs without CDK4 amplification
暂无分享,去创建一个
E. Campo | P. Jares | M. Pinyol | L. Conde | P. Fernández | A. Nadal | A. Cardesa | Coia Romeu | P. Fernandez
[1] H. Hermeking,et al. Evidence for a cancer-specific switch at the CDK4 promoter with loss of control by both USF and c-Myc , 2004, Oncogene.
[2] Y. Dong,et al. Cyclin D1‐CDK4 complex, a possible critical factor for cell proliferation and prognosis in laryngeal squamous cell carcinomas , 2001, International journal of cancer.
[3] E. Campo,et al. Disregulation of p16MTS1/CDK4I protein and mRNA expression is associated with gene alterations in squamous‐cell carcinoma of the larynx , 1999, International journal of cancer.
[4] C. Conti,et al. Coordinated changes in cell cycle machinery occur during keratinocyte terminal differentiation , 1999, Oncogene.
[5] J. Decaprio,et al. Role of CDK4 and p16INK4A in interleukin-6-mediated growth of multiple myeloma , 1997, Leukemia.
[6] M. Tsai,et al. Regulation of androgen-dependent prostatic cancer cell growth: androgen regulation of CDK2, CDK4, and CKI p16 genes. , 1997, Cancer research.
[7] E. Campo,et al. p21WAF1/Cip1 expression is associated with cell differentiation but not with p53 mutations in squamous cell carcinomas of the larynx , 1997, The Journal of pathology.
[8] E. Campo,et al. p16MTS1/CDK4I mutations and concomitant loss of heterozygosity at 9p21-23 are frequent events in squamous cell carcinoma of the larynx , 1997, Oncogene.
[9] P. Guldberg,et al. Complete scanning of the CDK4 gene by denaturing gradient gel electrophoresis: A novel missense mutation but low overall frequency of mutations in sporadic metastatic malignant melanoma , 1997, International journal of cancer.
[10] A. Bellacosa,et al. Altered expression of cyclin D1 and CDK4 genes in ovarian carcinomas , 1997, International journal of cancer.
[11] K. G. Coleman,et al. Identification of CDK4 Sequences Involved in Cyclin D1 and p16 Binding* , 1997, The Journal of Biological Chemistry.
[12] J. Bartek,et al. Mutual requirement of CDK4 and Myc in malignant transformation: evidence for cyclin D1/CDK4 and p16INK4A as upstream regulators of Myc , 1997, Oncogene.
[13] E. Hovig,et al. Involvement of the pRb/p16/cdk4/cyclin D1 pathway in the tumorigenesis of sporadic malignant melanomas. , 1996, British Journal of Cancer.
[14] T. Sekiya,et al. Homozygous deletion of the MTS1/p16 and MTS2/p15 genes and amplification of the CDK4 gene in glioma. , 1995, Oncogene.
[15] M. Serrano,et al. A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma , 1995, Science.
[16] T. Hunter,et al. Cyclins and cancer II: Cyclin D and CDK inhibitors come of age , 1994, Cell.
[17] C. James,et al. CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines. , 1994, Cancer research.
[18] F. Bosch,et al. PRAD-1/cyclin D1 gene amplification correlates with messenger RNA overexpression and tumor progression in human laryngeal carcinomas. , 1994, Cancer research.
[19] P. Meltzer,et al. Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2. , 1994, Cancer research.
[20] S. Shurtleff,et al. D-type cyclin-dependent kinase activity in mammalian cells , 1994, Molecular and cellular biology.
[21] A. Look,et al. Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas. , 1993, Cancer research.
[22] R. Weinberg,et al. Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[23] J. Ferlay,et al. Estimates of the worldwide incidence of eighteen major cancers in 1985 , 1993, International journal of cancer.
[24] Steven K. Hanks,et al. Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins , 1992, Cell.
[25] T. Hunter,et al. Cyclins and cancer , 1991, Cell.
[26] A. Robles,et al. Synchronized proliferation induced by 12-O-tetradecanoylphorbol-13-acetate treatment of mouse skin: an in vivo model for cell cycle regulation. , 1998, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[27] A. Sober,et al. Novel mutations in the p16/CDKN2A binding region of the cyclin-dependent kinase-4 gene. , 1998, Cancer research.
[28] N. Hayward,et al. Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma , 1996, Nature Genetics.