Epilepsy and intellectual disability linked protein Shrm4 interaction with GABABRs shapes inhibitory neurotransmission

[1]  T. Akiyama,et al.  PX-RICS-deficient mice mimic autism spectrum disorder in Jacobsen syndrome through impaired GABAA receptor trafficking , 2016, Nature Communications.

[2]  R. Cysneiros,et al.  Effect of diazepam on sociability of rats submitted to neonatal seizures , 2016, Data in brief.

[3]  D. Pinto,et al.  Identification of novel genetic causes of Rett syndrome-like phenotypes , 2016, Journal of Medical Genetics.

[4]  C. Mulle,et al.  Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex , 2015, Nature Communications.

[5]  Bianca Jupp,et al.  Social dominance in rats: effects on cocaine self-administration, novelty reactivity and dopamine receptor binding and content in the striatum , 2015, Psychopharmacology.

[6]  A. Jenkins,et al.  Ionotropic GABA and Glutamate Receptor Mutations and Human Neurologic Diseases , 2015, Molecular Pharmacology.

[7]  J. Crawley,et al.  GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism , 2015, Neuropsychopharmacology.

[8]  G. Deschênes,et al.  Double Xp11.22 deletion including SHROOM4 and CLCN5 associated with severe psychomotor retardation and Dent disease , 2015, Molecular Cytogenetics.

[9]  E. Bourel-ponchel,et al.  Phenotype–genotype correlations in 17 new patients with an Xp11.23p11.22 microduplication and review of the literature , 2015, American journal of medical genetics. Part A.

[10]  A. Fatemi,et al.  A novel variant in GABRB2 associated with intellectual disability and epilepsy , 2014, American journal of medical genetics. Part A.

[11]  S. Colombo,et al.  A positive signal prevents secretory membrane cargo from recycling between the Golgi and the ER , 2014, The EMBO journal.

[12]  T. Blanpied,et al.  Transport along the dendritic endoplasmic reticulum mediates the trafficking of GABAB receptors , 2014, Journal of Cell Science.

[13]  Giada Cellot,et al.  GABAergic Signaling as Therapeutic Target for Autism Spectrum Disorders , 2014, Front. Pediatr..

[14]  E. D’Angelo,et al.  Loss of hnRNP K Impairs Synaptic Plasticity in Hippocampal Neurons , 2014, The Journal of Neuroscience.

[15]  Q. Fan,et al.  Heterodimeric coiled-coil interactions of human GABAB receptor , 2014, Proceedings of the National Academy of Sciences.

[16]  Bi-Wen Peng,et al.  Role of TRPV1 in susceptibility to PTZ-induced seizure following repeated hyperthermia challenges in neonatal mice , 2014, Epilepsy & Behavior.

[17]  U. Rudolph,et al.  GABAA receptor subtypes: Therapeutic potential in Down syndrome, affective disorders, schizophrenia, and autism. , 2014, Annual review of pharmacology and toxicology.

[18]  M. Passafaro,et al.  The Neurobiology of X-Linked Intellectual Disability , 2013, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[19]  Francesca Fanelli,et al.  A Mixed Protein Structure Network and Elastic Network Model Approach to Predict the Structural Communication in Biomolecular Systems: The PDZ2 Domain from Tyrosine Phosphatase 1E As a Case Study. , 2013, Journal of chemical theory and computation.

[20]  R. Weinberg,et al.  Disruption of Arp2/3 Results in Asymmetric Structural Plasticity of Dendritic Spines and Progressive Synaptic and Behavioral Abnormalities , 2013, The Journal of Neuroscience.

[21]  C. B. Ransom,et al.  Postsynaptic GABAB Receptors Enhance Extrasynaptic GABAA Receptor Function in Dentate Gyrus Granule Cells , 2013, The Journal of Neuroscience.

[22]  William M. Connelly,et al.  GABAB Receptors Regulate Extrasynaptic GABAA Receptors , 2013, The Journal of Neuroscience.

[23]  C. Hoogenraad,et al.  TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites , 2013, Neuron.

[24]  L. Oberman.  mGluR antagonists and GABA agonists as novel pharmacological agents for the treatment of autism spectrum disorders , 2012, Expert opinion on investigational drugs.

[25]  M. Bear,et al.  Effects of STX209 (Arbaclofen) on Neurobehavioral Function in Children and Adults with Fragile X Syndrome: A Randomized, Controlled, Phase 2 Trial , 2012, Science Translational Medicine.

[26]  C. Schmidt,et al.  Endoplasmic Reticulum Sorting and Kinesin-1 Command the Targeting of Axonal GABAB Receptors , 2012, PloS one.

[27]  T. Smart,et al.  Sushi domains confer distinct trafficking profiles on GABAB receptors , 2012, Proceedings of the National Academy of Sciences.

[28]  David John Adams,et al.  γ-Aminobutyric Acid Type B (GABAB) Receptor Expression Is Needed for Inhibition of N-type (Cav2.2) Calcium Channels by Analgesic α-Conotoxins* , 2012, The Journal of Biological Chemistry.

[29]  M. Gassmann,et al.  Regulation of neuronal GABAB receptor functions by subunit composition , 2012, Nature Reviews Neuroscience.

[30]  Y. Goda,et al.  The X-Linked Intellectual Disability Protein TSPAN7 Regulates Excitatory Synapse Development and AMPAR Trafficking , 2012, Neuron.

[31]  E. Wanker,et al.  The X-chromosome-linked intellectual disability protein PQBP1 is a component of neuronal RNA granules and regulates the appearance of stress granules. , 2011, Human molecular genetics.

[32]  Mark Bates,et al.  Evaluation of fluorophores for optimal performance in localization-based super-resolution imaging , 2011, Nature Methods.

[33]  Prabuddha Sengupta,et al.  Probing protein heterogeneity in the plasma membrane using PALM and pair correlation analysis , 2011, Nature Methods.

[34]  M. Passafaro,et al.  The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2 , 2011, Human molecular genetics.

[35]  Stuart M. Baddeley,et al.  Gamma-aminobutyric acid type B (GABA(B)) receptor internalization is regulated by the R2 subunit. , 2011, The Journal of biological chemistry.

[36]  Benjamin B. Machta,et al.  Correlation Functions Quantify Super-Resolution Images and Estimate Apparent Clustering Due to Over-Counting , 2011, PloS one.

[37]  T. Fuchs,et al.  GABAA Receptor Trafficking-Mediated Plasticity of Inhibitory Synapses , 2011, Neuron.

[38]  Stuart M. Baddeley,et al.  GABAB receptor internalisation is regulated by the R2 subunit , 2011 .

[39]  Yingxi Lin,et al.  The contribution of GABAergic dysfunction to neurodevelopmental disorders. , 2011, Trends in molecular medicine.

[40]  J. Tardif,et al.  A Randomized Controlled, Phase 2 Trial of the Viral Serpin Serp-1 in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention , 2010, Circulation. Cardiovascular interventions.

[41]  J. Inazawa,et al.  Copy-number variations on the X chromosome in Japanese patients with mental retardation detected by array-based comparative genomic hybridization analysis , 2010, Journal of Human Genetics.

[42]  G. Blatt,et al.  Decreased GABAB receptors in the cingulate cortex and fusiform gyrus in Autism , 2010, Journal of neurochemistry.

[43]  Gavin Rumbaugh,et al.  Myosin IIb Regulates Actin Dynamics during Synaptic Plasticity and Memory Formation , 2010, Neuron.

[44]  B. Blagoev,et al.  GABAB Receptor Constituents Revealed by Tandem Affinity Purification from Transgenic Mice* , 2010, The Journal of Biological Chemistry.

[45]  Adam G. Carter,et al.  GABAB Receptors Modulate NMDA Receptor Calcium Signals in Dendritic Spines , 2010, Neuron.

[46]  J. Kapfhammer,et al.  The Sushi Domains of GABAB Receptors Function as Axonal Targeting Signals , 2010, The Journal of Neuroscience.

[47]  David R. Hampson,et al.  Increased GABAB Receptor-Mediated Signaling Reduces the Susceptibility of Fragile X Knockout Mice to Audiogenic Seizures , 2009, Molecular Pharmacology.

[48]  P. Thuras,et al.  Expression of GABAB Receptors Is Altered in Brains of Subjects with Autism , 2009, The Cerebellum.

[49]  C. Figueroa,et al.  The scaffold protein POSH regulates axon outgrowth. , 2008, Molecular biology of the cell.

[50]  Y. Jan,et al.  Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons , 2008, Nature Cell Biology.

[51]  M. Heilemann,et al.  Subdiffraction-resolution fluorescence imaging with conventional fluorescent probes. , 2008, Angewandte Chemie.

[52]  J. Cryan,et al.  Behavioral evaluation of mice deficient in GABAB(1) receptor isoforms in tests of unconditioned anxiety , 2007, Psychopharmacology.

[53]  S. Balasubramanian,et al.  GABAB Receptor Association with the PDZ Scaffold Mupp1 Alters Receptor Stability and Function* , 2006, Journal of Biological Chemistry.

[54]  T. Oertner,et al.  Differential Compartmentalization and Distinct Functions of GABAB Receptor Variants , 2006, Neuron.

[55]  G. Nowak,et al.  GABAergic hypotheses of anxiety and depression: focus on GABA-B receptors. , 2005, Drugs of today.

[56]  M. Farrant,et al.  Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors , 2005, Nature Reviews Neuroscience.

[57]  J. Cryan,et al.  Altered response to benzodiazepine anxiolytics in mice lacking GABA B(1) receptors. , 2004, European journal of pharmacology.

[58]  M. Gassmann,et al.  Molecular Structure and Physiological Functions of GABAB Receptors , 2004 .

[59]  M. Frotscher,et al.  Subcellular Localization of Metabotropic GABAB Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus , 2003, The Journal of Neuroscience.

[60]  I. Módy,et al.  Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by δ subunit-containing GABAA receptors , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[61]  G. Tedeschi,et al.  GABA(B) receptor 1 polymorphism (G1465A) is associated with temporal lobe epilepsy , 2003, Neurology.

[62]  D. Hess,et al.  Blood into brain after stroke. , 2002, Trends in molecular medicine.

[63]  R. Olsen,et al.  Behavior and Physiology of Mice Lacking the GABAA‐Receptor δ Subunit , 2002 .

[64]  D. Braida,et al.  3,4 methylenedioxymethamphetamine (ecstasy) impairs eight-arm radial maze performance and arm entry pattern in rats. , 2002, Behavioral neuroscience.

[65]  Richard B Thompson,et al.  High temporal resolution phase contrast MRI with multiecho acquisitions † , 2002, Magnetic resonance in medicine.

[66]  T. Mayhew,et al.  Relative labelling index: a novel stereological approach to test for non‐random immunogold labelling of organelles and membranes on transmission electron microscopy thin sections , 2002, Journal of microscopy.

[67]  David Baltimore,et al.  Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors , 2002, Science.

[68]  C. Lüscher,et al.  Epilepsy, Hyperalgesia, Impaired Memory, and Loss of Pre- and Postsynaptic GABAB Responses in Mice Lacking GABAB(1) , 2001, Neuron.

[69]  S. Moss,et al.  Constructing inhibitory synapses , 2001, Nature Reviews Neuroscience.

[70]  L. Prézeau,et al.  C-Terminal Interaction Is Essential for Surface Trafficking But Not for Heteromeric Assembly of GABAB Receptors , 2001, The Journal of Neuroscience.

[71]  R. Russell,et al.  The C-Terminal Domains of the GABAB Receptor Subunits Mediate Intracellular Trafficking But Are Not Required for Receptor Signaling , 2001, The Journal of Neuroscience.

[72]  Y. Jan,et al.  A Trafficking Checkpoint Controls GABAB Receptor Heterodimerization , 2000, Neuron.

[73]  Philippe Soriano,et al.  Shroom, a PDZ Domain–Containing Actin-Binding Protein, Is Required for Neural Tube Morphogenesis in Mice , 1999, Cell.

[74]  N. Hirokawa,et al.  Kinesin and dynein superfamily proteins in organelle transport and cell division. , 1998, Current opinion in cell biology.

[75]  Christian Lüscher,et al.  G Protein-Coupled Inwardly Rectifying K+ Channels (GIRKs) Mediate Postsynaptic but Not Presynaptic Transmitter Actions in Hippocampal Neurons , 1997, Neuron.

[76]  L. Jan,et al.  Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[77]  D. Braida,et al.  EEG power spectra and behavioral correlates in rats given chronic morphine. Lack of residual long-term EEG and neuronal changes. , 1995, Pharmacological research.

[78]  R. Vale,et al.  Cloning and localization of a conventional kinesin motor expressed exclusively in neurons , 1994, Neuron.

[79]  T. Blundell,et al.  Comparative protein modelling by satisfaction of spatial restraints. , 1993, Journal of molecular biology.

[80]  M. Manosevitz,et al.  Social Dominance in Inbred Mouse Strains , 1961, Nature.

[81]  Carlo Sala,et al.  Dendritic spines: the locus of structural and functional plasticity. , 2014, Physiological reviews.

[82]  T. Smart,et al.  Tracking Cell Surface Mobility of GPCRs Using alpha-Bungarotoxin-Linked Fluorophores , 2013 .

[83]  T. Smart,et al.  Tracking cell surface mobility of GPCRs using α-bungarotoxin-linked fluorophores. , 2013, Methods in enzymology.

[84]  F. Fanelli.  Modeling the structural communication in supramolecular complexes involving GPCRs. , 2012, Methods in molecular biology.

[85]  本田 尚三.  Copy-number variations on the X chromosome in Japanese patients with mental retardation detected by array-based comparative genomic hybridization analysis , 2011 .

[86]  I. Ial,et al.  Nature Communications , 2010, Nature Cell Biology.

[87]  G. Rossoni,et al.  Diazepam protects against the enhanced toxicity of cocaine adulterated with atropine. , 2008, Journal of pharmacological sciences.

[88]  J. Hildebrand,et al.  Shroom4 (Kiaa1202) is an actin-associated protein implicated in cytoskeletal organization. , 2007, Cell motility and the cytoskeleton.

[89]  J. Gécz,et al.  Disruptions of the novel KIAA1202 gene are associated with X-linked mental retardation , 2005, Human Genetics.

[90]  M. Gassmann,et al.  Molecular structure and physiological functions of GABA(B) receptors. , 2004, Physiological reviews.

[91]  R. Olsen,et al.  Behavior and physiology of mice lacking the GABAA-receptor delta subunit. , 2002, Epilepsia.

[92]  Masahito Watanabe,et al.  GABA and GABA receptors in the central nervous system and other organs. , 2002, International review of cytology.