USP10 Regulates p53 Localization and Stability by Deubiquitinating p53
暂无分享,去创建一个
J. Cheville | Z. Lou | K. Luo | Lizhi Zhang | Jian Yuan | Zhenkun Lou
[1] Pier Paolo Pandolfi,et al. The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network , 2008, Nature.
[2] T. Iwakuma,et al. The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss. , 2008, Genes & development.
[3] Eduardo Sontag,et al. Transcriptional control of human p53-regulated genes , 2008, Nature Reviews Molecular Cell Biology.
[4] W. Gu,et al. The p53–Mdm2–HAUSP complex is involved in p53 stabilization by HAUSP , 2007, Oncogene.
[5] U. Moll,et al. The Role of Ubiquitination in the Direct Mitochondrial Death Program of p53 , 2007, Cell cycle.
[6] Shishan Deng,et al. Over-expression of genes and proteins of ubiquitin specific peptidases (USPs) and proteasome subunits (PSs) in breast cancer tissue observed by the methods of RFDD-PCR and proteomics , 2007, Breast Cancer Research and Treatment.
[7] D. Allison,et al. Increased Expression of Thymidylate Synthetase (TS), Ubiquitin Specific Protease 10 (USP10) and Survivin is Associated with Poor Survival in Glioblastoma Multiforme (GBM) , 2006, Journal of Neuro-Oncology.
[8] Shili Duan,et al. Molecular recognition of p53 and MDM2 by USP7/HAUSP , 2006, Nature Structural &Molecular Biology.
[9] Wei Gu,et al. p53 ubiquitination: Mdm2 and beyond. , 2006, Molecular cell.
[10] Yigong Shi,et al. Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53–MDM2 Pathway , 2006, PLoS biology.
[11] H. Ovaa,et al. Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2. , 2005, Molecular cell.
[12] Petra de Graaf,et al. Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[13] N. Curtin,et al. Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM , 2004, Cancer Research.
[14] G. Wahl,et al. Accelerated MDM2 auto‐degradation induced by DNA‐damage kinases is required for p53 activation , 2004, The EMBO journal.
[15] Carlo Rago,et al. Tumour suppression: Disruption of HAUSP gene stabilizes p53 , 2004, Nature.
[16] Muyang Li,et al. A dynamic role of HAUSP in the p53-Mdm2 pathway. , 2004, Molecular cell.
[17] Muyang Li,et al. Mono- Versus Polyubiquitination: Differential Control of p53 Fate by Mdm2 , 2003, Science.
[18] J. Qin,et al. Parc A Cytoplasmic Anchor for p53 , 2003, Cell.
[19] J. Qin,et al. Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization , 2002, Nature.
[20] U. Moll,et al. Nuclear degradation of p53 occurs during down‐regulation of the p53 response after DNA damage , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[21] D. Woods,et al. C-Terminal Ubiquitination of p53 Contributes to Nuclear Export , 2001, Molecular and Cellular Biology.
[22] D. Lane,et al. Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53. , 2001, Experimental cell research.
[23] T. Roberts,et al. Induction of p53-Independent Apoptosis by Simian Virus 40 Small t Antigen , 2001, Journal of Virology.
[24] R. Abraham. Cell cycle checkpoint signaling through the ATM and ATR kinases. , 2001, Genes & development.
[25] Giulio Draetta,et al. Ras–GAP SH3 domain binding protein (G3BP) is a modulator of USP10, a novel human ubiquitin specific protease , 2001, Oncogene.
[26] E. Appella,et al. Post-translational modifications and activation of p53 by genotoxic stresses. , 2001, European journal of biochemistry.
[27] S. T. Kim,et al. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage. , 2001, Genes & development.
[28] J. Levine,et al. Surfing the p53 network , 2000, Nature.
[29] C. Maki,et al. The MDM2 RING-finger domain is required to promote p53 nuclear export , 2000, Nature Cell Biology.
[30] K. Tsai,et al. An intact HDM2 RING-finger domain is required for nuclear exclusion of p53 , 2000, Nature Cell Biology.
[31] S. Elledge,et al. DNA damage-induced activation of p53 by the checkpoint kinase Chk2. , 2000, Science.
[32] T. Halazonetis,et al. Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. , 2000, Genes & development.
[33] Y Taya,et al. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. , 2000, Genes & development.
[34] C Béroud,et al. p53 Website and analysis of p53 gene mutations in human cancer: Forging a link between epidemiology and carcinogenesis , 2000, Human mutation.
[35] Y. Shiloh,et al. Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[36] G. Wahl,et al. A leucine‐rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking , 1999, The EMBO journal.
[37] A. Levine,et al. Nuclear Export Is Required for Degradation of Endogenous p53 by MDM2 and Human Papillomavirus E6 , 1998, Molecular and Cellular Biology.
[38] Hirofumi Tanaka,et al. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 , 1997, FEBS letters.
[39] Yoichi Taya,et al. DNA Damage-Induced Phosphorylation of p53 Alleviates Inhibition by MDM2 , 1997, Cell.
[40] R A Jungmann,et al. c-Myc transactivation of LDH-A: implications for tumor metabolism and growth. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[41] M. Oren,et al. Mdm2 promotes the rapid degradation of p53 , 1997, Nature.
[42] R. Everett,et al. A novel ubiquitin‐specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein , 1997, The EMBO journal.
[43] M. Kubbutat,et al. Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability , 1997, Molecular and cellular biology.
[44] K. Kinzler,et al. Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. , 1995, Cancer research.
[45] D. Lane,et al. p53, guardian of the genome , 1992, Nature.
[46] M. Scheffner,et al. A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. , 1991, The EMBO journal.
[47] Y Taya,et al. Enhanced phosphorylation of p53 by ATM in response to DNA damage. , 1998, Science.
[48] D. Lane,et al. Cancer. p53, guardian of the genome. , 1992, Nature.