Direct and indirect antioxidant properties of inducers of cytoprotective proteins.
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[1] S. Hecht,et al. Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice. , 2005, Cancer research.
[2] Lingyun Wu,et al. Dietary approaches to positively influence fetal determinants of adult health , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[3] H. Mukhtar,et al. Curcumin for chemoprevention of colon cancer. , 2007, Cancer letters.
[4] W. Pearson,et al. Nomenclature for mammalian soluble glutathione transferases. , 2005, Methods in enzymology.
[5] A. Dinkova-Kostova. Protection against cancer by plant phenylpropenoids: induction of mammalian anticarcinogenic enzymes. , 2002, Mini reviews in medicinal chemistry.
[6] H. Bartsch,et al. Inhibition of angiogenesis and endothelial cell functions are novel sulforaphane-mediated mechanisms in chemoprevention , 2006, Molecular Cancer Therapeutics.
[7] Shyam Biswal,et al. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. , 2007, Annual review of pharmacology and toxicology.
[8] Carole L. Linster,et al. Vitamin C , 2007, The FEBS journal.
[9] B. Mannervik,et al. Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes. , 1997, The Biochemical journal.
[10] Nathan V. Matusheski,et al. Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, sulforaphane and sulforaphane nitrile. , 2001, Journal of agricultural and food chemistry.
[11] John M Pezzuto,et al. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[12] S. R. Spencer,et al. Induction of glutathione transferases and NAD(P)H:quinone reductase by fumaric acid derivatives in rodent cells and tissues. , 1990, Cancer research.
[13] L. Landi,et al. DT-Diaphorase maintains the reduced state of ubiquinones in lipid vesicles thereby promoting their antioxidant function. , 1997, Free radical biology & medicine.
[14] Lingyun Wu,et al. Dietary approach to attenuate oxidative stress, hypertension, and inflammation in the cardiovascular system. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[15] V. Sondak,et al. Targeting events in melanoma carcinogenesis for the prevention of melanoma , 2006, Expert review of anticancer therapy.
[16] R. Mulcahy,et al. Regulation of γ-glutamylcysteine synthetase subunit gene expression: Insights into transcriptional control of antioxidant defenses , 2000, Free radical research.
[17] P. Karplus,et al. A Novel Mechanism of Chemoprotection by Sulforaphane , 2004, Cancer Research.
[18] K. Kanki,et al. Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters. , 2006, Cancer letters.
[19] Barbara A Halkier,et al. Glucosinolate research in the Arabidopsis era. , 2002, Trends in plant science.
[20] A. Dinkova-Kostova,et al. Phenolic Michael reaction acceptors: combined direct and indirect antioxidant defenses against electrophiles and oxidants. , 2007, Medicinal chemistry (Shariqah (United Arab Emirates)).
[21] P. Talalay. Chemoprotection against cancer by induction of phase 2 enzymes. , 2000, BioFactors.
[22] L. Wattenberg. Chemoprevention of cancer. , 1996, Preventive medicine.
[23] S. Biswal,et al. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. , 2002, Cancer research.
[24] B. Mannervik,et al. Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation. , 1998, The Biochemical journal.
[25] C. Yabe-Nishimura,et al. Curcumin activates human glutathione S-transferase P1 expression through antioxidant response element. , 2007, Toxicology letters.
[26] A. Meister. Glutathione-ascorbic acid antioxidant system in animals. , 1994, The Journal of biological chemistry.
[27] A. Conney. Induction of drug-metabolizing enzymes: a path to the discovery of multiple cytochromes P450. , 2003, Annual review of pharmacology and toxicology.
[28] J. Ross,et al. Curcumin Induces Heme Oxygenase-1 in Hepatocytes and Is Protective in Simulated Cold Preservation and Warm Reperfusion Injury , 2006, Transplantation.
[29] A. Quattrone,et al. Curcumin activates defensive genes and protects neurons against oxidative stress. , 2006, Antioxidants & redox signaling.
[30] K. N. Rajasekharan,et al. Antimutagenic and anticarcinogenic activity of natural and synthetic curcuminoids. , 1996, Mutation research.
[31] F. Maerki,et al. [Vitamin K reductase, preparation and properties]. , 1960, Biochemische Zeitschrift.
[32] K. Itoh,et al. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. , 1997, Biochemical and biophysical research communications.
[33] Jing Yang,et al. Protective effects of isoliquiritigenin in transient middle cerebral artery occlusion-induced focal cerebral ischemia in rats. , 2006, Pharmacological research.
[34] N. Juge,et al. Molecular basis for chemoprevention by sulforaphane: a comprehensive review , 2007, Cellular and Molecular Life Sciences.
[35] P. Gascoyne,et al. The effect of H2O2 upon thioredoxin-enriched lens epithelial cells. , 1988, The Journal of biological chemistry.
[36] P. Talalay,et al. Biochemical studies on the mechanisms by which dietary antioxidants suppress mutagenic activity. , 1978, Advances in enzyme regulation.
[37] T. Kensler,et al. The role of Keap1 in cellular protective responses. , 2005, Chemical research in toxicology.
[38] T. Kensler. Chemoprevention by inducers of carcinogen detoxication enzymes. , 1997, Environmental health perspectives.
[39] P. P. Chang,et al. Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells. , 2006, Cancer research.
[40] Y. Surh,et al. Heme oxygenase-1 as a potential therapeutic target for hepatoprotection. , 2006, Journal of biochemistry and molecular biology.
[41] S. R. Spencer,et al. The potency of inducers of NAD(P)H:(quinone-acceptor) oxidoreductase parallels their efficiency as substrates for glutathione transferases. Structural and electronic correlations. , 1991, The Biochemical journal.
[42] C. Rao,et al. Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate. , 2000, Carcinogenesis.
[43] Z. Sadeghinejad,et al. Dietary approach to decrease aging-related CNS inflammation , 2005, Nutritional neuroscience.
[44] P. Jemth,et al. Phospholipid hydroperoxide glutathione peroxidase activity of human glutathione transferases. , 1998, The Biochemical journal.
[45] Elias S. J. Arnér,et al. Regeneration of the antioxidant ubiquinol by lipoamide dehydrogenase, thioredoxin reductase and glutathione reductase , 2003, BioFactors.
[46] C. Cho,et al. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[47] D. Ross,et al. NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms. , 2000, Chemico-biological interactions.
[48] B. Halliwell,et al. Free radicals in biology and medicine , 1985 .
[49] P. Forsmark-Andrée,et al. Ubiquinol: an endogenous antioxidant in aerobic organisms , 2004, The clinical investigator.
[50] Y. Surh,et al. Cancer chemoprevention with dietary phytochemicals , 2003, Nature Reviews Cancer.
[51] L. Landi,et al. The role of DT-diaphorase in the maintenance of the reduced antioxidant form of coenzyme Q in membrane systems. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[52] S. Rhee,et al. Thioredoxin-dependent peroxide reductase from yeast. , 1994, The Journal of biological chemistry.
[53] T. Kensler,et al. Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[54] F. Campbell,et al. Chemopreventive properties of curcumin. , 2005, Future oncology.
[55] Y. Tyurina,et al. Recycling and Redox Cycling of Phenolic Antioxidants , 1998, Annals of the New York Academy of Sciences.
[56] J. Morrow,et al. The cyclopentenone product of lipid peroxidation, 15-A(2t)-isoprostane (8-isoprostaglandin A(2)), is efficiently conjugated with glutathione by human and rat glutathione transferase A4-4. , 2002, Chemical research in toxicology.
[57] T. Kensler,et al. Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[58] H. Bartsch,et al. Nuclear Factor κB Is a Molecular Target for Sulforaphane-mediated Anti-inflammatory Mechanisms* , 2001, The Journal of Biological Chemistry.
[59] W. Berkel,et al. Pro-oxidant activity of flavonoids induces EpRE-mediated gene expression. , 2006, Chemical research in toxicology.
[60] B. Mannervik,et al. Glutathione transferase M2-2 catalyzes conjugation of dopamine and dopa o-quinones. , 2000, Biochemical and biophysical research communications.
[61] J. Pezzuto,et al. Potential cancer chemopreventive constituents of the seeds of Dipteryx odorata (tonka bean). , 2003, Journal of natural products.
[62] J. Gardiner,et al. CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane. , 1996, Carcinogenesis.
[63] Anuj Sharma,et al. Multiple molecular targets in cancer chemoprevention by curcumin , 2006, The AAPS Journal.
[64] Masayuki Yamamoto,et al. Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species. , 2006, Advances in enzyme regulation.
[65] Jing Zhao,et al. Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents , 2006, Neuroscience Letters.
[66] H. Bartsch,et al. Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms. , 2001, The Journal of biological chemistry.
[67] Y. Kan,et al. NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[68] A. Holmgren,et al. Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system. , 2007, American journal of physiology. Heart and circulatory physiology.
[69] B. Day,et al. Reduction of phenoxyl radicals by thioredoxin results in selective oxidation of its SH-groups to disulfides. An antioxidant function of thioredoxin. , 1995, Biochemistry.
[70] M. Massiah,et al. Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[71] Masayuki Yamamoto,et al. Nrf2-Keap1 defines a physiologically important stress response mechanism. , 2004, Trends in molecular medicine.
[72] A. Dinkova-Kostova,et al. Protection against electrophile and oxidative stress by induction of phase 2 genes: the quest for the elusive sensor that responds to inducers. , 2004, Advances in enzyme regulation.
[73] A. Conney,et al. Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2. , 2006, Cancer research.
[74] R. Foresti,et al. Changes in temperature modulate heme oxygenase-1 induction by curcumin in renal epithelial cells. , 2003, Biochemical and biophysical research communications.
[75] M. Tanito,et al. Delay of photoreceptor degeneration in tubby mouse by sulforaphane , 2007, Journal of neurochemistry.
[76] W. Pearson,et al. Increased synthesis of glutathione S-transferases in response to anticarcinogenic antioxidants. Cloning and measurement of messenger RNA. , 1983, The Journal of biological chemistry.
[77] R. Brigelius-Flohé,et al. Glutathione peroxidases and redox-regulated transcription factors , 2006, Biological chemistry.
[78] D. Liebler,et al. The Reduction of α-Tocopherolquinone by Human NAD(P)H:Quinone Oxidoreductase: The Role of α-Tocopherolhydroquinone as a Cellular Antioxidant , 1997 .
[79] R. North. Down-regulation of the antitumor immune response. , 1985, Advances in cancer research.
[80] A. Viviani,et al. The enzymatic reduction of K‐vitamins incorporated in the membrane of liposomes , 1975, FEBS letters.
[81] K. Angioi-Duprez,et al. Efficacy of Sulforaphane in Eradicating Helicobacter pylori in Human Gastric Xenografts Implanted in Nude Mice , 2003, Antimicrobial Agents and Chemotherapy.
[82] J. Pezzuto,et al. Quinone reductase induction as a biomarker for cancer chemoprevention. , 2006, Journal of natural products.
[83] P. Talalay,et al. Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[84] A. Dinkova-Kostova,et al. Chemical structures of inducers of nicotinamide quinone oxidoreductase 1 (NQO1). , 2004, Methods in enzymology.
[85] D. Liebler,et al. The reduction of alpha-tocopherolquinone by human NAD(P)H: quinone oxidoreductase: the role of alpha-tocopherolhydroquinone as a cellular antioxidant. , 1997, Molecular pharmacology.
[86] Huawei Zeng,et al. Thioredoxin reductase in human hepatoma cells is transcriptionally regulated by sulforaphane and other electrophiles via an antioxidant response element. , 2003, The Journal of nutrition.
[87] Masaki Tanito,et al. Upregulation of thioredoxin system via Nrf2-antioxidant responsive element pathway in adaptive-retinal neuroprotection in vivo and in vitro. , 2007, Free radical biology & medicine.
[88] S. Wehage,et al. Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts. , 2006, Cancer letters.
[89] D. Butterfield,et al. Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer's disease. , 2003, The Italian journal of biochemistry.
[90] M. Tanito,et al. Sulforaphane induces thioredoxin through the antioxidant-responsive element and attenuates retinal light damage in mice. , 2005, Investigative ophthalmology & visual science.
[91] Fusheng Yang,et al. Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo* , 2005, Journal of Biological Chemistry.
[92] R. Foresti,et al. Curcumin reduces cold storage-induced damage in human cardiac myoblasts , 2007, Experimental & Molecular Medicine.
[93] A. Kong,et al. Cancer chemoprevention of intestinal polyposis in ApcMin/+ mice by sulforaphane, a natural product derived from cruciferous vegetable. , 2006, Carcinogenesis.
[94] G. Powis,et al. Properties and biological activities of thioredoxins. , 2001, Annual review of pharmacology and toxicology.
[95] L. Gamet-Payrastre. Signaling pathways and intracellular targets of sulforaphane mediating cell cycle arrest and apoptosis. , 2006, Current cancer drug targets.
[96] R. Cole,et al. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[97] Vincent Zoete,et al. Redox ranking of inducers of a cancer-protective enzyme via the energy of their highest occupied molecular orbital. , 2004, Free radical biology & medicine.
[98] A. Dinkova-Kostova,et al. Relation of structure of curcumin analogs to their potencies as inducers of Phase 2 detoxification enzymes. , 1999, Carcinogenesis.
[99] R. Hondal,et al. Thioredoxin reductase. , 2000, The Biochemical journal.
[100] A. Dinkova-Kostova,et al. Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: The indirect antioxidant effects of sulforaphane , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[101] A. Dinkova-Kostova,et al. Chemoprotective properties of phenylpropenoids, bis(benzylidene)cycloalkanones, and related Michael reaction acceptors: correlation of potencies as phase 2 enzyme inducers and radical scavengers. , 1998, Journal of medicinal chemistry.
[102] J. Fahey,et al. Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes. , 1999, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[103] P. Talalay. The War against Cancer: New Hope , 1999 .
[104] Nathan V. Matusheski,et al. Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion. , 2006, Cancer letters.
[105] A. Khar,et al. Biological effects of curcumin and its role in cancer chemoprevention and therapy. , 2006, Anti-cancer agents in medicinal chemistry.
[106] E. Ho,et al. Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apcmin mice , 2006 .
[107] P. Talalay,et al. Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[108] Paul Talalay,et al. Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[109] J. Fahey,et al. Chemoprotection against cancer by phase 2 enzyme induction. , 1995, Toxicology letters.
[110] Jawed Alam,et al. Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element. , 2003, The Biochemical journal.