AG8 reduces hypoxia-induced triple negative breast cancer metastasis by stemness regulation

[1]  P. Nguyen,et al.  Anti-cancer activity of green synthesized silver nanoparticles using Ardisia gigantifolia leaf extract against gastric cancer cells. , 2023, Biochemical and biophysical research communications.

[2]  Weibo Dai,et al.  Anti-colorectal cancer of Ardisia gigantifolia Stapf. and targets prediction via network pharmacology and molecular docking study , 2023, BMC Complementary Medicine and Therapies.

[3]  Almaz Borjigidai,et al.  Ardisia gigantifolia stapf (Primulaceae): A review of ethnobotany, phytochemistry, pharmacology, clinical application, and toxicity. , 2023, Journal of ethnopharmacology.

[4]  Hong Yan,et al.  Triterpenoid Saponin AG8 from Ardisia gigantifolia stapf. Induces Triple Negative Breast Cancer Cells Apoptosis through Oxidative Stress Pathway , 2020, Oxidative medicine and cellular longevity.

[5]  I. Berindan‐Neagoe,et al.  Hypoxia: Overview on Hypoxia-Mediated Mechanisms with a Focus on the Role of HIF Genes , 2019, International journal of molecular sciences.

[6]  Alexandra G. Smith,et al.  Autophagy, cancer stem cells and drug resistance , 2019, The Journal of pathology.

[7]  M. Todaro,et al.  Meeting the Challenge of Targeting Cancer Stem Cells , 2019, Front. Cell Dev. Biol..

[8]  K. Suntharalingam,et al.  The Next Generation of Anticancer Metallopharmaceuticals: Cancer Stem Cell‐Active Inorganics , 2018, Chembiochem : a European journal of chemical biology.

[9]  P. Kim,et al.  c-MYC Drives Breast Cancer Metastasis to the Brain, but Promotes Synthetic Lethality with TRAIL , 2018, Molecular Cancer Research.

[10]  Shanshan Liu,et al.  Association Between Hypoxia-Inducible Factor-2α (HIF-2α) Expression and Colorectal Cancer and Its Prognostic Role: a Systematic Analysis , 2018, Cellular Physiology and Biochemistry.

[11]  Yue Liu,et al.  OCT4B regulates p53 and p16 pathway genes to prevent apoptosis of breast cancer cells. , 2018, Oncology letters.

[12]  A. Shajahan-Haq,et al.  MYC-Driven Pathways in Breast Cancer Subtypes , 2017, Biomolecules.

[13]  G. Semenza,et al.  Hypoxia-Inducible Factors: Master Regulators of Cancer Progression. , 2016, Trends in cancer.

[14]  Kok-Gan Chan,et al.  MiRNA Transcriptome Profiling of Spheroid-Enriched Cells with Cancer Stem Cell Properties in Human Breast MCF-7 Cell Line , 2016, International journal of biological sciences.

[15]  J. Menéndez,et al.  Pro-Oxidant Activity of Amine-Pyridine-Based Iron Complexes Efficiently Kills Cancer and Cancer Stem-Like Cells , 2015, PloS one.

[16]  N. Sinha,et al.  Therapeutic targets of triple‐negative breast cancer: a review , 2015, British journal of pharmacology.

[17]  Corbin E. Meacham,et al.  Tumour heterogeneity and cancer cell plasticity , 2013, Nature.

[18]  R. Wenger,et al.  Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression. , 2013, Cancer research.

[19]  J. Balko,et al.  TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer. , 2013, The Journal of clinical investigation.

[20]  F. Papaccio,et al.  Cancer stem cells in solid tumors: an overview and new approaches for their isolation and characterization , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[21]  E. Y. Lee,et al.  Biomarkers to Target Heterogeneous Breast Cancer Stem Cells , 2012, Journal of molecular biomarkers & diagnosis.

[22]  G. von Minckwitz,et al.  Neoadjuvant treatments for triple-negative breast cancer (TNBC). , 2012, Annals of oncology : official journal of the European Society for Medical Oncology.

[23]  Jingxuan Pan,et al.  Reactive oxygen species in cancer stem cells. , 2012, Antioxidants & redox signaling.

[24]  Ping Liu,et al.  Cytotoxic triterpenoid saponins from Ardisia gigantifolia. , 2012, Planta medica.

[25]  P. Gimotty,et al.  Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation , 2012, Oncogene.

[26]  Brian Keith,et al.  HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression , 2011, Nature Reviews Cancer.

[27]  Hyunggee Kim,et al.  Nanog-induced dedifferentiation of p53-deficient mouse astrocytes into brain cancer stem-like cells. , 2011, Biochemical and biophysical research communications.

[28]  Mandip Singh,et al.  Antitumor Activity of Noscapine in Combination with Doxorubicin in Triple Negative Breast Cancer , 2011, PloS one.

[29]  S. Borstnar,et al.  Triple negative breast cancer – prognostic factors and survival , 2010, Radiology and oncology.

[30]  Ping Liu,et al.  Triterpenoid saponins from Ardisia gigantifolia. , 2010, Chemical & pharmaceutical bulletin.

[31]  Ping Liu,et al.  New triterpenoid sapoin from Ardisia gigantifolia Stapf. , 2010 .

[32]  Charles M Perou,et al.  A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer. , 2009, Cancer research.

[33]  Zhong Yun,et al.  Hypoxic tumor microenvironment and cancer cell differentiation. , 2009, Current molecular medicine.

[34]  H. Iwase,et al.  Hypoxia-inducible factor 1α is closely linked to an aggressive phenotype in breast cancer , 2008, Breast Cancer Research and Treatment.

[35]  A. Rosenberg,et al.  Differences in breast carcinoma characteristics in newly diagnosed African–American and Caucasian patients , 2007, Cancer.

[36]  B. Fredholm,et al.  Toxic effects of cobalt in primary cultures of mouse astrocytes. Similarities with hypoxia and role of HIF-1alpha. , 2007, Biochemical pharmacology.

[37]  Christopher H. Contag,et al.  MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer , 2004, Nature.

[38]  G. Dontu,et al.  In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. , 2003, Genes & development.

[39]  A. Sparks,et al.  Identification of c-MYC as a target of the APC pathway. , 1998, Science.

[40]  E. Monti,et al.  HIF-1 as a target for cancer chemotherapy, chemosensitization and chemoprevention. , 2011, Current molecular pharmacology.

[41]  Adrian L. Harris,et al.  Hypoxia — a key regulatory factor in tumour growth , 2002, Nature Reviews Cancer.