MERCUROCHROME-220 SOLUBLE INTRAVENOUSLY IN CHRONIC GONORRHEA AND COMPLICATIONS: REPORT OF TEN CASES TREATED AT THE OHIO STATE PENITENTIARY
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Mercurochrome-220 soluble is "the disodium salt of 2: 7-dibromo-4-hydroxymercurifluorescein, containing 23 to 24 per cent, of mercury."1It is a strong and rapidly acting germicide, originally devised as a potent local antiseptic. Its value as an irrigant in gonococcus urethritis, cystitis and infections of the kidney pelvis has been thoroughly demonstrated. Piper's2idea of the intravenous injection of mercurochrome for the purpose of rendering the blood stream bactericidal in puerperal sepsis was a new field for its use, and one of his concluding statements stands forth impressively: "A solution of mercurochrome given, intravenously, in the proper dosage, appears, in some cases, to be of great value and to have no deleterious effects." Later, Young and Hill3reported its intravenous use in the treatment of septicemia and local infections. They state that, in two cases, "the results were almost miraculous, the patients being verily snatched from the jaws
[1] H. Young,et al. THE TREATMENT OF SEPTICEMIA AND LOCAL INFECTIONS: BY INTRAVENOUS INJECTIONS OF MERCUROCHROME-220 SOLUBLE AND OF GENTIAN VIOLET , 1924 .
[2] E. B. Piper. The Treatment of Puerperal Sepsis by the Use of Mercurochrome Intravenously with a Report of Animal Experimentation in the Chemical Disinfection of the Blood , 2022 .