Preinfusion polyfunctional anti-CD19 chimeric antigen receptor T cells associate with clinical outcomes in NHL Running Head: Polyfunctional CAR T cell-associated clinical outcomes
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S. Rosenberg | S. Mackay | J. Rossi | A. Bot | Rong Fan | J. Kochenderfer | P. Paczkowski | James R. Heath | Jing Zhou | Kaiser | B. Flynn | Yueh-wei Shen | K. Morse | Alaina | C. Ng | Kyle Gallatin | Tom Cain | Colin Ng
[1] Alaina Kaiser,et al. Single-cell multiplexed cytokine profiling of CD19 CAR-T cells reveals a diverse landscape of polyfunctional antigen-specific response , 2017, Journal of Immunotherapy for Cancer.
[2] J. Friedberg,et al. Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[3] S. Heimfeld,et al. Immunotherapy of non-Hodgkin’s lymphoma with a defined ratio of CD8+ and CD4+ CD19-specific chimeric antigen receptor–modified T cells , 2016, Science Translational Medicine.
[4] G. Wertheim,et al. Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia. , 2016, Cancer discovery.
[5] B. Jabri,et al. IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destruction , 2015, Nature Reviews Immunology.
[6] David L. Porter,et al. Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia , 2015, Science Translational Medicine.
[7] D. Pe’er,et al. Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands , 2015, Proceedings of the National Academy of Sciences.
[8] S. Grupp,et al. Engineered T cells for cancer therapy , 2014, Cancer Immunology, Immunotherapy.
[9] Mario Roederer,et al. Single-cell technologies for monitoring immune systems , 2014, Nature Immunology.
[10] S. Rosenberg,et al. Treating B-cell cancer with T cells expressing anti-CD19 chimeric antigen receptors , 2013, Nature Reviews Clinical Oncology.
[11] Michel Sadelain,et al. The basic principles of chimeric antigen receptor design. , 2013, Cancer discovery.
[12] David Baltimore,et al. Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy. , 2013, Cancer discovery.
[13] W. Wilson,et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. , 2012, Blood.
[14] S. Kern,et al. Th17 cells are long lived and retain a stem cell-like molecular signature. , 2011, Immunity.
[15] Y. Li,et al. Interleukin-17-secreting T cells in neuromyelitis optica and multiple sclerosis during relapse , 2011, Journal of Clinical Neuroscience.
[16] S. Rosenberg,et al. CD8+ Enriched “Young” Tumor Infiltrating Lymphocytes Can Mediate Regression of Metastatic Melanoma , 2010, Clinical Cancer Research.
[17] W. Zou,et al. TH17 cells in tumour immunity and immunotherapy , 2010, Nature Reviews Immunology.
[18] E. Tolosa,et al. Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis. , 2009, Brain : a journal of neurology.
[19] W. Wilson,et al. Construction and Preclinical Evaluation of an Anti-CD19 Chimeric Antigen Receptor , 2009, Journal of immunotherapy.
[20] M. Roederer,et al. T-cell quality in memory and protection: implications for vaccine design , 2008, Nature Reviews Immunology.
[21] I. Türbachova,et al. DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3+ conventional T cells , 2007, European journal of immunology.
[22] T. Waldmann. The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design , 2006, Nature Reviews Immunology.
[23] A. Zelenetz,et al. Age-adjusted International Prognostic Index predicts autologous stem cell transplantation outcome for patients with relapsed or primary refractory diffuse large B-cell lymphoma. , 2003, Blood.
[24] J. Sheridan,et al. Requirement of MIP-1 alpha for an inflammatory response to viral infection. , 1995, Science.
[25] K. Matsushima,et al. Essential involvement of interleukin‐8 (IL‐8) in acute inflammation , 1994, Journal of leukocyte biology.