Cerebral hemodynamics during discrimination of prosodic and semantic emotion in speech studied by transcranial doppler ultrasonography.

Simultaneous measurement of blood flow velocity (BFV) in the middle cerebral arteries was achieved by transcranial Doppler ultrasonography in 36 right-handed volunteers who were instructed to identify the emotion conveyed by prosody or semantics of a number of sentences. The tasks were performed under 2 levels of interference: neutral versus discordant affective value of the modality that had to be ignored. A multivariate analysis of variance showed a significant bilateral increase in BFV during the discordant conditions reflecting increased attentional demand. A significant left-hemispheric lateralization of BFV was observed as emotional semantics were labeled. When attention was shifted to affective prosody, the lateralization effect disappeared as a result of a marked increase in right-hemispheric BFV.

[1]  K. Heilman,et al.  The role of the right hemisphere in emotional communication. , 1991, Brain : a journal of neurology.

[2]  M. Pell,et al.  The neural bases of prosody: Insights from lesion studies and neuroimaging , 1999 .

[3]  R. C. Oldfield.  The assessment and analysis of handedness: the Edinburgh inventory. , 1971, Neuropsychologia.

[4]  Rune Aaslid,et al.  Transcranial Doppler Sonography , 1986, Springer Vienna.

[5]  M. Pell.  Recognition of prosody following unilateral brain lesion: influence of functional and structural attributes of prosodic contours , 1998, Neuropsychologia.

[6]  Marc D. Pell,et al.  Unilateral Brain Damage, Prosodic Comprehension Deficits, and the Acoustic Cues to Prosody , 1997, Brain and Language.

[7]  J. Stirling,et al.  Dichotically presented emotionally intoned words produce laterality differences as a function of localisation task , 2000, Laterality.

[8]  Wolfgang Grodd,et al.  Lateralized fMRI activation at the level of the motor cortex during linguistic and affective prosody production tasks , 2001, NeuroImage.

[9]  Between-task habituation in functional transcranial Doppler ultrasonography. , 1999, Neuroreport.

[10]  E B Ringelstein,et al.  Transcranial Doppler sonography: anatomical landmarks and normal velocity values. , 1990, Ultrasound in medicine & biology.

[11]  N L Browse,et al.  Transcranial Doppler measurement of middle cerebral artery blood flow velocity: a validation study. , 1986, Stroke.

[12]  G. Gainotti.  The neuropsychology of emotions and psychiatric disturbances , 1991 .

[13]  Klaus Willmes,et al.  Hemispheric Asymmetry in the Recognition of Emotional Attitude Conveyed by Facial Expression, Prosody and Propositional Speech , 1997, Cortex.

[14]  E Altenmüller,et al.  Cortical activation patterns of affective speech processing depend on concurrent demands on the subvocal rehearsal system. A DC-potential study. , 2000, Brain : a journal of neurology.

[15]  K. Heilman,et al.  Understanding emotional prosody activates right hemisphere regions. , 1996, Archives of neurology.

[16]  Guy Vingerhoets,et al.  Cerebral blood flow velocity changes during dichotic listening with directed or divided attention: a transcranial Doppler ultrasonography study , 2001, Neuropsychologia.

[17]  M. Bryden,et al.  Dichotic laterality effects obtained with emotional words. , 1988 .

[18]  Hiroshi Fukuda,et al.  Changes of regional cerebral blood flow during listening to an unfamiliar spoken language , 1993, Neuroscience Letters.

[19]  C. Mateer,et al.  Right hemisphere appreciation of prosodic and linguistic indications of implicit attitude , 1985, Brain and Language.

[20]  Shari R. Baum,et al.  Compensation for jaw fixation by aphasic patients under conditions of increased articulatory demands: a follow-up study , 1999 .

[21]  H. Whitaker,et al.  Effects of right and left hemisphere cerebrovascular lesions on discrimination of prosodic and semantic aspects of affect in sentences , 1992, Brain and Language.

[22]  D. Lancker,et al.  Cerebral Lateralization of Pitch Cues in the Linguistic Signal , 1980 .

[23]  K. Gutbrod,et al.  Determination of cognitive hemispheric dominance by "stereo" transcranial Doppler sonography. , 1995, Stroke.

[24]  K M Heilman,et al.  Spared comprehension of emotional prosody in a patient with global aphasia. , 1999, Neuropsychiatry, neuropsychology, and behavioral neurology.

[25]  H. Damasio,et al.  Auditory perception of temporal and spectral events in patients with focal left and right cerebral lesions , 1990, Brain and Language.

[26]  A. Harders,et al.  A transcranial Doppler study of blood flow velocity in the middle cerebral arteries performed at rest and during mental activities. , 1989, Stroke.

[27]  M. Raichle,et al.  Localization of a human system for sustained attention by positron emission tomography , 1991, Nature.

[28]  K. Heilman,et al.  Comprehension of emotional prosody following unilateral hemispheric lesions: Processing defect versus distraction defect , 1987, Neuropsychologia.

[29]  M Deppe,et al.  Successive activation of both cerebral hemispheres during cued word generation , 1996, Neuroreport.

[30]  Guy Vingerhoets,et al.  Transcranial Doppler Ultrasonography Monitoring of Cerebral Hemodynamics During Performance of Cognitive Tasks: A Review , 2000, Neuropsychology Review.

[31]  M. Pell,et al.  The Ability to Perceive and Comprehend Intonation in Linguistic and Affective Contexts by Brain-Damaged Adults , 1997, Brain and Language.

[32]  C Caltagirone,et al.  Bilateral Simultaneous Assessment of Cerebral Flow Velocity during Mental Activity , 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[33]  R. C. Oldfield.  THE ASSESSMENT AND ANALYSIS OF HANDEDNESS , 1971 .

[34]  Donald A. Robin,et al.  The role of callosal connections in speech prosody , 1988, Brain and Language.

[35]  Andrew Kertesz,et al.  Lesion localization in acquired deficits of emotional expression and comprehension , 1990, Brain and Cognition.

[36]  Joan C. Borod,et al.  Cerebral mechanisms underlying facial, prosodic, and lexical emotional expression: A review of neuropsychological studies and methodological issues. , 1993 .

[37]  J. Sidtis,et al.  The identification of affective-prosodic stimuli by left- and right-hemisphere-damaged subjects: all errors are not created equal. , 1992, Journal of speech and hearing research.

[38]  E Altenmüller,et al.  The cortical processing of perceived emotion: a DC‐potential study on affective speech prosody , 1997, Neuroreport.

[39]  A G Harders,et al.  Brain activity and blood flow velocity changes: a transcranial Doppler study. , 1989, The International journal of neuroscience.

[40]  Tracy L. Luks,et al.  Hemispheric Involvement in the Perception of Syntactic Prosody Is Dynamically Dependent on Task Demands , 1998, Brain and Language.

[41]  H. Kirshner,et al.  Affective prosodic disturbance subsequent to right hemisphere stroke: A clinical application , 1998, Journal of Neurolinguistics.