Lifestyle weight-loss intervention may attenuate methylation aging: the CENTRAL MRI randomized controlled trial

[1]  P. Stadler,et al.  DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: the CENTRAL trial , 2020, Genome medicine.

[2]  F. Bellanti,et al.  The Mediterranean Diet Slows Down the Progression of Aging and Helps to Prevent the Onset of Frailty: A Narrative Review , 2019, Nutrients.

[3]  Michal Rein,et al.  The beneficial effects of Mediterranean diet over low-fat diet may be mediated by decreasing hepatic fat content. , 2019, Journal of hepatology.

[4]  C. Franceschi,et al.  The Impact of Caloric Restriction on the Epigenetic Signatures of Aging , 2019, International journal of molecular sciences.

[5]  Yanbin Dong,et al.  Effects of Vitamin D3 Supplementation on Epigenetic Aging in Overweight and Obese African Americans With Suboptimal Vitamin D Status: A Randomized Clinical Trial , 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

[6]  S. Horvath,et al.  Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data , 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

[7]  L. Liang,et al.  Exposure to Polycyclic Aromatic Hydrocarbons and Accelerated DNA Methylation Aging , 2018, Environmental health perspectives.

[8]  D. English,et al.  Association of DNA Methylation-Based Biological Age With Health Risk Factors and Overall and Cause-Specific Mortality , 2018, American journal of epidemiology.

[9]  N. Roetker,et al.  Prospective Study of Epigenetic Age Acceleration and Incidence of Cardiovascular Disease Outcomes in the ARIC Study (Atherosclerosis Risk in Communities) , 2018, Circulation. Genomic and precision medicine.

[10]  E. Ingelsson,et al.  Methylation‐based estimated biological age and cardiovascular disease , 2018, European journal of clinical investigation.

[11]  Michal Rein,et al.  Effect of Distinct Lifestyle Interventions on Mobilization of Fat Storage Pools: CENTRAL Magnetic Resonance Imaging Randomized Controlled Trial , 2017, Circulation.

[12]  Luis E. B. Bettio,et al.  The effects of aging in the hippocampus and cognitive decline , 2017, Neuroscience & Biobehavioral Reviews.

[13]  J. Ilich,et al.  Aging human body: changes in bone, muscle and body fat with consequent changes in nutrient intake. , 2017, The Journal of endocrinology.

[14]  Nancy L. Pedersen,et al.  Biological Age Predictors , 2017, EBioMedicine.

[15]  M. Levine,et al.  Epigenetic clock analysis of diet, exercise, education, and lifestyle factors , 2017, Aging.

[16]  Jean-Philippe Fortin,et al.  Preprocessing, normalization and integration of the Illumina HumanMethylationEPIC array with minfi , 2016, bioRxiv.

[17]  A. Martí,et al.  Adherence to Mediterranean diet is associated with methylation changes in inflammation-related genes in peripheral blood cells , 2016, Journal of Physiology and Biochemistry.

[18]  M. Levine,et al.  DNA methylation-based measures of biological age: meta-analysis predicting time to death , 2016, Aging.

[19]  M. Levine,et al.  An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease , 2016, Genome Biology.

[20]  H. Brenner,et al.  Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort , 2016, Clinical Epigenetics.

[21]  J. Godos,et al.  Lifestyle changes for the treatment of nonalcoholic fatty liver disease: a review of observational studies and intervention trials , 2016, Therapeutic advances in gastroenterology.

[22]  J. Vaupel,et al.  University of Southern Denmark DNA methylation age is associated with mortality in a longitudinal Danish twin study , 2015 .

[23]  A. Rule,et al.  Structural and Functional Changes With the Aging Kidney. , 2016, Advances in chronic kidney disease.

[24]  D. Williamson,et al.  Is 5% weight loss a satisfactory criterion to define clinically significant weight loss? , 2015, Obesity.

[25]  H. Huikuri,et al.  Non-Alcoholic Fatty Liver Disease as a Predictor of Atrial Fibrillation in Middle-Aged Population (OPERA Study) , 2015, PloS one.

[26]  C. Byrne,et al.  NAFLD: a multisystem disease. , 2015, Journal of hepatology.

[27]  S. Horvath,et al.  DNA methylation age of blood predicts all-cause mortality in later life , 2015, Genome Biology.

[28]  D. Bishop,et al.  Exercise training and DNA methylation in humans , 2015, Acta physiologica.

[29]  P. Eline Slagboom,et al.  MethylAid: visual and interactive quality control of large Illumina 450k datasets , 2014, Bioinform..

[30]  Rafael A. Irizarry,et al.  Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays , 2014, Bioinform..

[31]  S. Horvath.  DNA methylation age of human tissues and cell types , 2013, Genome Biology.

[32]  Stephanie A. Tammen,et al.  Epigenetics: the link between nature and nurture. , 2013, Molecular aspects of medicine.

[33]  T. Ideker,et al.  Genome-wide methylation profiles reveal quantitative views of human aging rates. , 2013, Molecular cell.

[34]  André Tchernof,et al.  Pathophysiology of human visceral obesity: an update. , 2013, Physiological reviews.

[35]  Peter Langfelder,et al.  Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects , 2012, BMC Genomics.

[36]  C. Fox,et al.  Ectopic Fat Depots and Cardiovascular Disease , 2011, Circulation.

[37]  DeMarc Hickson,et al.  Fatty Liver, Abdominal Visceral Fat, and Cardiometabolic Risk Factors: The Jackson Heart Study , 2011, Arteriosclerosis, thrombosis, and vascular biology.

[38]  P. Calder,et al.  Non-alcoholic fatty liver disease and cardiovascular risk: metabolic aspects and novel treatments , 2011, Endocrine.

[39]  T. He,et al.  Epigenetic Regulation of Mesenchymal Stem Cells: A Focus on Osteogenic and Adipogenic Differentiation , 2011, Stem cells international.

[40]  J. Mathers,et al.  Diet induced epigenetic changes and their implications for health , 2011, Acta physiologica.

[41]  Udo Hoffmann,et al.  Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat: The Framingham heart study , 2010, Hepatology.

[42]  E. Gibney,et al.  Epigenetics and gene expression , 2010, Heredity.

[43]  J Bernadette Moore,et al.  Non-alcoholic fatty liver disease: the hepatic consequence of obesity and the metabolic syndrome , 2010, Proceedings of the Nutrition Society.

[44]  M. Fraga.  Genetic and epigenetic regulation of aging. , 2009, Current opinion in immunology.

[45]  Christopher D Byrne,et al.  Metabolic disturbances in non-alcoholic fatty liver disease. , 2009, Clinical science.

[46]  Norbert Stefan,et al.  Causes and metabolic consequences of Fatty liver. , 2008, Endocrine reviews.

[47]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[48]  M. Extermann,et al.  Cancer and aging. An evolving panorama. , 2000, Hematology/oncology clinics of North America.