Atlas-based rib-bone detection in chest X-rays

This paper investigates using rib-bone atlases for automatic detection of rib-bones in chest X-rays (CXRs). We built a system that takes patient X-ray and model atlases as input and automatically computes the posterior rib borders with high accuracy and efficiency. In addition to conventional atlas, we propose two alternative atlases: (i) automatically computed rib bone models using Computed Tomography (CT) scans, and (ii) dual energy CXRs. We test the proposed approach with each model on 25 CXRs from the Japanese Society of Radiological Technology (JSRT) dataset and another 25 CXRs from the National Library of Medicine CXR dataset. We achieve an area under the ROC curve (AUC) of about 95% for Montgomery and 91% for JSRT datasets. Using the optimal operating point of the ROC curve, we achieve a segmentation accuracy of 88.91±1.8% for Montgomery and 85.48±3.3% for JSRT datasets. Our method produces comparable results with the state-of-the-art algorithms. The performance of our method is also excellent on challenging X-rays as it successfully addressed the rib-shape variance between patients and number of visible rib-bones due to patient respiration.

[1]  Jing-Wein Wang,et al.  A nonparametric-based rib suppression method for chest radiographs , 2012, Comput. Math. Appl..

[2]  D. Louis Collins,et al.  Towards accurate, automatic segmentation of the hippocampus and amygdala from MRI by augmenting ANIMAL with a template library and label fusion , 2010, NeuroImage.

[3]  Juha Koikkalainen,et al.  Fast and robust multi-atlas segmentation of brain magnetic resonance images , 2010, NeuroImage.

[4]  Ulas Bagci,et al.  Efficient ribcage segmentation from CT scans using shape features , 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[5]  Kunio Doi,et al.  Suppression of the contrast of ribs in chest radiographs by means of massive training artificial neural network , 2004, SPIE Medical Imaging.

[6]  S Katsuragawa,et al.  Automated selection of regions of interest for quantitative analysis of lung textures in digital chest radiographs. , 1993, Medical physics.

[7]  William M. Wells,et al.  Simultaneous truth and performance level estimation (STAPLE): an algorithm for the validation of image segmentation , 2004, IEEE Transactions on Medical Imaging.

[8]  Timothy F. Cootes,et al.  Active Appearance Models , 1998, ECCV.

[9]  Antonio Torralba,et al.  SIFT Flow: Dense Correspondence across Scenes and Its Applications , 2011, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[10]  K. Doi,et al.  Image feature analysis and computer-aided diagnosis in digital radiography: automated detection of pneumothorax in chest images. , 1992, Medical physics.

[11]  Bram van Ginneken,et al.  Automatic delineation of ribs in frontal chest radiographs , 2000, Medical Imaging: Image Processing.

[12]  Mert R. Sabuncu,et al.  A Generative Model for Image Segmentation Based on Label Fusion , 2010, IEEE Transactions on Medical Imaging.

[13]  J. H. Kulick,et al.  Automatic Rib Detection in Chest Radiographs , 1977, IJCAI.

[14]  A. Ardeshir Goshtasby,et al.  Automatic detection of rib borders in chest radiographs , 1995, IEEE Trans. Medical Imaging.

[15]  Bram van Ginneken,et al.  Segmentation of anatomical structures in chest radiographs using supervised methods: a comparative study on a public database , 2006, Medical Image Anal..

[16]  Peter de Souza Automatic rib detection in chest radiographs , 1983, Comput. Vis. Graph. Image Process..

[17]  Carlos Ortiz-de-Solorzano,et al.  Combination Strategies in Multi-Atlas Image Segmentation: Application to Brain MR Data , 2009, IEEE Transactions on Medical Imaging.

[18]  Bram van Ginneken,et al.  Segmentation of the posterior ribs in chest radiographs using iterated contextual pixel classification , 2006, IEEE Transactions on Medical Imaging.

[19]  Nicolas Cherbuin,et al.  Optimal weights for local multi-atlas fusion using supervised learning and dynamic information (SuperDyn): Validation on hippocampus segmentation , 2011, NeuroImage.

[20]  Daniel Rueckert,et al.  Segmentation of Brain MRI in Young Children , 2007, MICCAI.

[21]  Clement J. McDonald,et al.  Automatic Tuberculosis Screening Using Chest Radiographs , 2014, IEEE Transactions on Medical Imaging.

[22]  K Doi,et al.  Localization of inter-rib spaces for lung texture analysis and computer-aided diagnosis in digital chest images. , 1988, Medical physics.

[23]  Harry Wechsler,et al.  Automatic Detection Of Rib Contours in Chest Radiographs , 1975, IJCAI.

[24]  Antonio Torralba,et al.  SIFT Flow: Dense Correspondence across Different Scenes , 2008, ECCV.

[25]  Max Mignotte,et al.  Three-dimensional biplanar reconstruction of scoliotic rib cage using the estimation of a mixture of probabilistic prior models , 2005, IEEE Transactions on Biomedical Engineering.

[26]  S Katsuragawa,et al.  Image feature analysis and computer-aided diagnosis in digital radiography: detection and characterization of interstitial lung disease in digital chest radiographs. , 1988, Medical physics.

[27]  G LoweDavid,et al.  Distinctive Image Features from Scale-Invariant Keypoints , 2004 .

[28]  S Katsuragawa,et al.  Image feature analysis and computer-aided diagnosis in digital radiography: classification of normal and abnormal lungs with interstitial disease in chest images. , 1989, Medical physics.

[29]  John F. Canny,et al.  A Computational Approach to Edge Detection , 1986, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[30]  Hasan Ogul,et al.  Eliminating rib shadows in chest radiographic images providing diagnostic assistance , 2016, Comput. Methods Programs Biomed..

[31]  Bram van Ginneken,et al.  Filter learning: Application to suppression of bony structures from chest radiographs , 2006, Medical Image Anal..

[32]  K. Doi,et al.  Development of a digital image database for chest radiographs with and without a lung nodule: receiver operating characteristic analysis of radiologists' detection of pulmonary nodules. , 2000, AJR. American journal of roentgenology.

[33]  Clement J. McDonald,et al.  Lung Segmentation in Chest Radiographs Using Anatomical Atlases With Nonrigid Registration , 2014, IEEE Transactions on Medical Imaging.

[34]  Timothy F. Cootes,et al.  Active Shape Models-Their Training and Application , 1995, Comput. Vis. Image Underst..

[35]  Subhasis Chaudhuri,et al.  Detection of Rib Shadows in Digital Chest Radiographs , 1997, ICIAP.

[36]  Roberto Manduchi,et al.  Bilateral filtering for gray and color images , 1998, Sixth International Conference on Computer Vision (IEEE Cat. No.98CH36271).

[37]  Elsa D. Angelini,et al.  Accurate and robust shape descriptors for the identification of RIB cage structures in CT-images with Random Forests , 2013, 2013 IEEE 10th International Symposium on Biomedical Imaging.

[38]  Phaneendra Madala Interactive web-based track editing and management , 2012 .

[39]  Max A. Viergever,et al.  Label Fusion in Atlas-Based Segmentation Using a Selective and Iterative Method for Performance Level Estimation (SIMPLE) , 2010, IEEE Transactions on Medical Imaging.

[40]  Farida Cheriet,et al.  Semiautomatic Detection of Scoliotic Rib Borders From Posteroanterior Chest Radiographs , 2012, IEEE Transactions on Biomedical Engineering.

[41]  Max A. Viergever,et al.  Multi-Atlas-Based Segmentation With Local Decision Fusion—Application to Cardiac and Aortic Segmentation in CT Scans , 2009, IEEE Transactions on Medical Imaging.

[42]  Daniel Rueckert,et al.  Multi-atlas based segmentation of brain images: Atlas selection and its effect on accuracy , 2009, NeuroImage.

[43]  Alejandro F. Frangi,et al.  Automatic construction of multiple-object three-dimensional statistical shape models: application to cardiac modeling , 2002, IEEE Transactions on Medical Imaging.

[44]  Matthijs C. Dorst Distinctive Image Features from Scale-Invariant Keypoints , 2011 .

[45]  Dinggang Shen,et al.  Construction of multi-region-multi-reference atlases for neonatal brain MRI segmentation , 2010, NeuroImage.

[46]  Daniel Beard,et al.  Firefly: web-based interactive tool for the visualization and validation of image processing algorithms , 2009 .