Neurocognitive correlates of processing food-related stimuli in a Go/No-go paradigm

We examined the neurocognitive correlates of processing food-related stimuli in healthy young adults. Event-related potential (ERP) data were collected while 48 participants completed a computerized Go/No-go task consisting of food and nonfood images. Separately, we assessed participants' self-reported levels of external, restrained, and emotional eating behaviors as well as trait impulsivity, behavioral activation/inhibition, and performance on the Stroop Color-Word Test. We found that across participants, food images elicited significantly enhanced P3(00) and slow-wave ERP components. The difference in slow-wave components elicited by food and nonfood images was correlated with Stroop interference scores. Food images also elicited significantly enhanced N2(00) components, but only in female participants. The difference between N2 components elicited by food and nonfood images was related to body mass index and scores of external eating in females. Overall, these data suggest that processing food-related stimuli recruits distinct patterns of cortical activity, that the magnitude of these effects is related to behavioral and cognitive variables, and that the neurocognitive correlates of processing food-cues may be at least partly dissociable between males and females.

[1]  K. Flegal,et al.  Prevalence and trends in obesity among US adults, 1999-2008. , 2010, JAMA.

[2]  J E Frijters,et al.  Eating behavior, personality traits and body mass in women. , 1985, Addictive behaviors.

[3]  A. Kelley,et al.  Neural systems recruited by drug- and food-related cues: Studies of gene activation in corticolimbic regions , 2005, Physiology & Behavior.

[4]  N. Volkow,et al.  Food and drug reward: overlapping circuits in human obesity and addiction. , 2012, Current topics in behavioral neurosciences.

[5]  J. Polich,et al.  Neuropsychology and neuropharmacology of P3a and P3b. , 2006, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[6]  Christie Golden,et al.  Stroop Color and Word Test: Manual for Clinical and Experimental Uses. , 1978 .

[7]  Tatjana van Strien,et al.  The Dutch Eating Behavior Questionnaire (DEBQ) for assessment of restrained, emotional, and external eating behavior , 1986 .

[8]  E. Falk,et al.  Impulsivity and inhibitory control deficits are associated with unhealthy eating in young adults , 2012, Appetite.

[9]  P. Muris,et al.  Enhanced processing of food-related pictures in female external eaters , 2009, Appetite.

[10]  J. Patton,et al.  Factor structure of the Barratt impulsiveness scale. , 1995, Journal of clinical psychology.

[11]  M. Herrmann,et al.  Alcohol cue-reactivity in heavy and light social drinkers as revealed by event-related potentials. , 2001, Alcohol and alcoholism.

[12]  L. Nickerson,et al.  Cue reactivity in cannabis-dependent adolescents. , 2011, Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors.

[13]  S. Kühn,et al.  Common biology of craving across legal and illegal drugs – a quantitative meta‐analysis of cue‐reactivity brain response , 2011, The European journal of neuroscience.

[14]  P. Muris,et al.  Food-related Stroop interference in obese and normal-weight individuals: behavioral and electrophysiological indices. , 2010, Eating behaviors.

[15]  Jonathan R. Folstein,et al.  Novelty and conflict in the categorization of complex stimuli. , 2008, Psychophysiology.

[16]  M. Lowe,et al.  Neural correlates of individual differences related to appetite , 2009, Physiology & Behavior.

[17]  J. Polivy,et al.  External cues in the control of food intake in humans: The sensory-normative distinction , 2008, Physiology & Behavior.

[18]  G. Breese,et al.  Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. , 2011, Pharmacology & therapeutics.

[19]  Chrysa D. Lithari,et al.  Are Females More Responsive to Emotional Stimuli? A Neurophysiological Study Across Arousal and Valence Dimensions , 2009, Brain Topography.

[20]  B. Feige,et al.  To eat or not to eat? Availability of food modulates the electrocortical response to food pictures in restrained eaters , 2010, Appetite.

[21]  Nora D. Volkow,et al.  The Addictive Dimensionality of Obesity , 2013, Biological Psychiatry.

[22]  M. Herrmann,et al.  Event-related potentials and cue-reactivity in alcoholism. , 2000, Alcoholism, clinical and experimental research.

[23]  S. Grüsser,et al.  Specific cue reactivity on computer game-related cues in excessive gamers. , 2007, Behavioral neuroscience.

[24]  Caroline Reid,et al.  From motivation to behaviour: A model of reward sensitivity, overeating, and food preferences in the risk profile for obesity , 2007, Appetite.

[25]  A. Mendrek,et al.  Sex differences in memory of emotional images: a behavioral and electrophysiological investigation. , 2012, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[26]  C. Carver,et al.  Behavioral inhibition, behavioral activation, and affective responses to impending reward and punishment: The BIS/BAS Scales , 1994 .

[27]  J. Deakin,et al.  Electrophysiological evidence of the motivational salience of drug cues in opiate addiction , 2007, Psychological Medicine.

[28]  R. Baños,et al.  Executive Functions Profile in Extreme Eating/Weight Conditions: From Anorexia Nervosa to Obesity , 2012, PloS one.

[29]  A. Grace,et al.  Identifying the neural circuitry of alcohol craving and relapse vulnerability , 2009, Addiction biology.

[30]  Rajita Sinha,et al.  Modeling stress and drug craving in the laboratory: implications for addiction treatment development , 2009, Addiction biology.

[31]  N. Squires,et al.  Two varieties of long-latency positive waves evoked by unpredictable auditory stimuli in man. , 1975, Electroencephalography and clinical neurophysiology.

[32]  A. Convit,et al.  Disinhibited Eating in Obese Adolescents Is Associated With Orbitofrontal Volume Reductions and Executive Dysfunction , 2011, Obesity.

[33]  R. Knight,et al.  Neural origins of the P300. , 2000, Critical reviews in neurobiology.

[34]  A. Kübler,et al.  Enhanced behavioral inhibition in restrained eaters. , 2011, Eating behaviors.

[35]  Cornelis J Stam,et al.  Two new neurophysiological indices of cocaine craving: evoked brain potentials and cue modulated startle reflex , 2004, Journal of psychopharmacology.

[36]  P. Muris,et al.  Food cue-elicited brain potentials in obese and healthy-weight individuals. , 2007, Appetite.

[37]  K. Mogg,et al.  External eating, impulsivity and attentional bias to food cues , 2011, Appetite.

[38]  P. Lang.  International affective picture system (IAPS) : affective ratings of pictures and instruction manual , 2005 .

[39]  Herta Flor,et al.  Psychophysiological responses to drug‐associated stimuli in chronic heavy cannabis use , 2008, The European journal of neuroscience.

[40]  Christina F. Lavallee,et al.  Electroencephalography of response inhibition tasks: functional networks and cognitive contributions. , 2013, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[41]  C. Murphy,et al.  Restrained eaters show altered brain response to food odor , 2006, Physiology & Behavior.

[42]  J. Wardle,et al.  Dietary restraint and self-regulation in eating behavior , 2012, International Journal of Obesity.

[43]  S. Grüsser,et al.  Cue-induced auditory evoked potentials in alcoholism , 2007, Clinical Neurophysiology.

[44]  Ingmar H. A. Franken,et al.  Differences in attention to food and food intake between overweight/obese and normal-weight females under conditions of hunger and satiety , 2010, Appetite.

[45]  S. Gortmaker,et al.  Health and economic burden of the projected obesity trends in the USA and the UK , 2011, The Lancet.

[46]  J. Polich.  Updating P300: An integrative theory of P3a and P3b , 2007, Clinical Neurophysiology.

[47]  N. Volkow,et al.  Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology , 2008, Philosophical Transactions of the Royal Society B: Biological Sciences.

[48]  A. Lawrence,et al.  Individual Differences in Reward Drive Predict Neural Responses to Images of Food , 2006, The Journal of Neuroscience.

[49]  T W Picton,et al.  The P300 Wave of the Human Event‐Related Potential , 1992, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[50]  Ingmar H. A. Franken,et al.  The modified Trait and State Food-Cravings Questionnaires: Development and validation of a general index of food craving , 2007, Appetite.

[51]  Karin Mogg,et al.  Attentional and approach biases for pictorial food cues. Influence of external eating , 2009, Appetite.

[52]  Kee Namkoong,et al.  Increased P3 amplitudes induced by alcohol-related pictures in patients with alcohol dependence. , 2004, Alcoholism, clinical and experimental research.

[53]  S. Kotz,et al.  Conflict processing is modulated by positive emotion: ERP data from a flanker task , 2011, Behavioural Brain Research.