Testing hypotheses of aging in long-lived mice of the genus Peromyscus: association between longevity and mitochondrial stress resistance, ROS detoxification pathways, and DNA repair efficiency
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S. Austad | Z. Ungvari | A. Csiszar | Arthur James Cooper | P. Pacher | P. Mukhopadhyay | B. Krasnikov | N. Labinskyy | A. Podlutsky | N. Podlutskaya
[1] S. Austad,et al. Oxidative stress in vascular senescence: lessons from successfully aging species. , 2008, Frontiers in bioscience : a journal and virtual library.
[2] S. Austad,et al. Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity , 2007, Aging cell.
[3] D. Zorov,et al. The mitochondrion as Janus Bifrons , 2007, Biochemistry (Moscow).
[4] M. Madesh,et al. Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy , 2007, Nature Protocols.
[5] B. Cravatt,et al. Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase. , 2007, American journal of physiology. Heart and circulatory physiology.
[6] Z. Ungvari,et al. Increased mitochondrial H2O2 production promotes endothelial NF- B activation in aged rat arteries , 2007 .
[7] P. Pacher,et al. Simple quantitative detection of mitochondrial superoxide production in live cells. , 2007, Biochemical and biophysical research communications.
[8] G. Pierce,et al. Direct Evidence of Endothelial Oxidative Stress With Aging in Humans: Relation to Impaired Endothelium-Dependent Dilation and Upregulation of Nuclear Factor-&kgr;B , 2007, Circulation research.
[9] D. Bourdette,et al. Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis , 2007, Proceedings of the National Academy of Sciences.
[10] Z. Ungvari,et al. Resveratrol Increases Vascular Oxidative Stress Resistance , 2007, American journal of physiology. Heart and circulatory physiology.
[11] Z. Ungvari,et al. Vascular aging in the longest‐living rodent, the naked mole‐rat , 2007, American journal of physiology. Heart and circulatory physiology.
[12] A. Galecki,et al. Skin‐derived fibroblasts from long‐lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone , 2007, Aging cell.
[13] Z. Ungvari,et al. Comparison of endothelial function, O2.‐ and H2O2 production and vascular oxidative stress resistance between the longest‐living rodent, the naked mole‐rat and mice , 2006, American journal of physiology. Heart and circulatory physiology.
[14] S. Shenouda,et al. Up-Regulation of Heme Oxygenase Provides Vascular Protection in an Animal Model of Diabetes through Its Antioxidant and Antiapoptotic Effects , 2006, Journal of Pharmacology and Experimental Therapeutics.
[15] Z. Ungvari,et al. Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen. , 2006, Current medicinal chemistry.
[16] S. Marklund,et al. Phenotypes of Mice Lacking Extracellular Superoxide Dismutase and Copper- and Zinc-containing Superoxide Dismutase* , 2006, Journal of Biological Chemistry.
[17] C. Epstein,et al. Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging , 2006, Mechanisms of Ageing and Development.
[18] R. S. Sohal,et al. Enhanced catabolism of mitochondrial superoxide/hydrogen peroxide and aging in transgenic Drosophila. , 2005, The Biochemical journal.
[19] B. Kristal,et al. Comparative kinetic analysis reveals that inducer-specific ion release precedes the mitochondrial permeability transition. , 2005, Biochimica et biophysica acta.
[20] N. Abraham,et al. Heme oxygenase and the cardiovascular-renal system. , 2005, Free radical biology & medicine.
[21] Z. Ungvari,et al. Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging. , 2005, Current vascular pharmacology.
[22] M. Emond,et al. Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria , 2005, Science.
[23] C. Leeuwenburgh,et al. Muscle fiber‐specific apoptosis and TNF‐α signaling in sarcopenia are attenuated by life‐long calorie restriction , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[24] A. Richardson,et al. Transgenic Mice Overexpressing Glutathione Peroxidase 4 Are Protected against Oxidative Stress-induced Apoptosis* , 2004, Journal of Biological Chemistry.
[25] Z. Ungvari,et al. Vascular Inflammation in Aging , 2004, Herz.
[26] R. Adkins,et al. Phylogeny and divergence-date estimates of rapid radiations in muroid rodents based on multiple nuclear genes. , 2004, Systematic biology.
[27] C. Epstein,et al. Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress. , 2004, Free radical biology & medicine.
[28] H. Naito,et al. Age‐associated increases in oxidative stress and nuclear transcription factor κB activation are attenuated in rat liver by regular exercise , 2004 .
[29] C. Peterson,et al. Cellular machineries for chromosomal DNA repair. , 2004, Genes & development.
[30] Z. Ungvari,et al. Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging. , 2004, Physiological genomics.
[31] Daniel E. Hall,et al. In vivo visualization of aging-associated gene transcription: evidence for free radical theory of aging , 2004, Experimental Gerontology.
[32] Anja K. Brunet-Rossinni. Reduced free-radical production and extreme longevity in the little brown bat (Myotis lucifugus) versus two non-flying mammals , 2004, Mechanisms of Ageing and Development.
[33] C. Epstein,et al. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. , 2003, Physiological genomics.
[34] R. D'Agostino,et al. Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study. , 2003, The American journal of medicine.
[35] T. Hintze,et al. NAD(P)H oxidase-generated superoxide anion accounts for reduced control of myocardial O2 consumption by NO in old Fischer 344 rats. , 2003, American journal of physiology. Heart and circulatory physiology.
[36] A. Richardson,et al. Oxidative Damage to DNA and Aging , 2003, Exercise and sport sciences reviews.
[37] Z. Ungvari,et al. Aging‐induced proinflammatory shift in cytokine expression profile in rat coronary arteries , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[38] E. Eldrup,et al. Circulating levels of TNF-alpha and IL-6-relation to truncal fat mass and muscle mass in healthy elderly individuals and in patients with type-2 diabetes , 2003, Mechanisms of Ageing and Development.
[39] H. Ischiropoulos,et al. Oxidative stress and nitration in neurodegeneration: cause, effect, or association? , 2003, The Journal of clinical investigation.
[40] Richard Weindruch,et al. Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[41] Z. Ungvari,et al. Aging-Induced Phenotypic Changes and Oxidative Stress Impair Coronary Arteriolar Function , 2002, Circulation research.
[42] G. Hajnóczky,et al. Ca2+ marks: Miniature calcium signals in single mitochondria driven by ryanodine receptors , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[43] Pál Pacher,et al. Propagation of the apoptotic signal by mitochondrial waves , 2001, The EMBO journal.
[44] H. Remmen,et al. Oxidative damage to mitochondria and aging , 2001, Experimental Gerontology.
[45] G. Hajnóczky,et al. Mitochondrial Ca2+ Signaling and Cardiac Apoptosis , 2001, Neurosignals.
[46] A. Dominiczak,et al. Superoxide Excess in Hypertension and Aging: A Common Cause of Endothelial Dysfunction , 2001, Hypertension.
[47] R. Weindruch,et al. Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria. , 1998, Free radical biology & medicine.
[48] D. Zorov,et al. The permeability transition pore induced under anaerobic conditions in mitochondria energized with ATP , 1998, FEBS letters.
[49] C. Caramelo,et al. Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats. , 1998, Circulation research.
[50] Sohal Rs,et al. Role of oxidative stress in senescence. , 1998 .
[51] D. Zorov,et al. The Ca2+‐induced pore opening in mitochondria energized by succinate‐ferricyanide electron transport , 1997, FEBS letters.
[52] D. Zorov,et al. Mitochondria Revisited. Alternative Functions of Mitochondria , 1997, Bioscience reports.
[53] A. Salminen,et al. Age-related changes in the regulation of transcription factor NF-κB in rat brain , 1997, Neuroscience Letters.
[54] R. Weindruch,et al. Oxidative Stress, Caloric Restriction, and Aging , 1996, Science.
[55] S. Novgorodov,et al. Permeability transition pore of the inner mitochondrial membrane can operate in two open states with different selectivities , 1996, Journal of bioenergetics and biomembranes.
[56] A. Salminen,et al. Aging-induced up-regulation of nuclear binding activities of oxidative stress responsive NF-kB transcription factor in mouse cardiac muscle. , 1996, Journal of molecular and cellular cardiology.
[57] R. S. Sohal,et al. Comparison of mitochondrial pro-oxidant generation and anti-oxidant defenses between rat and pigeon: possible basis of variation in longevity and metabolic potential , 1993, Mechanisms of Ageing and Development.
[58] R. S. Sohal,et al. Biochemical correlates of longevity in two closely related rodent species. , 1993, Biochemical and biophysical research communications.
[59] R. Ross. The pathogenesis of atherosclerosis: a perspective for the 1990s , 1993, Nature.
[60] T. Lindahl. Instability and decay of the primary structure of DNA , 1993, Nature.
[61] R. S. Sohal,et al. Relationship between Antioxidants, Prooxidants, and the Aging Process a , 1992, Annals of the New York Academy of Sciences.
[62] R. S. Sohal,et al. Mitochondrial production of pro-oxidants and cellular senescence. , 1992, Mutation research.
[63] R. S. Sohal,et al. Relationship between antioxidant defenses and longevity in different mammalian species , 1990, Mechanisms of Ageing and Development.
[64] D. Brash,et al. Longevity-dependent organ-specific accumulation of DNA damage in two closely related murine species , 1984, Mechanisms of Ageing and Development.
[65] S. Marklund,et al. Radiation resistance and the CuZn superoxide dismutase, Mn superoxide dismutase, catalase, and glutathione peroxidase activities of seven human cell lines. , 1984, Radiation research.
[66] R. Reiter,et al. Effects of advancing age on the ultrastructure of pinealocytes in the male white-footed mouse (Peromyscus leucopus). , 1982, The Journal of experimental zoology.
[67] J. Peluso,et al. Effects of advancing age on the hypothalamic-pituitary-ovarian axis of the female white-footed mouse (Peromyscus leucopus). , 1980, Experimental aging research.
[68] G. Sacher,et al. DNA repair in a short- and a long-lived rodent species. , 1979, Journal of gerontology.
[69] S. D'Ambrosio,et al. Longevity, stability and DNA repair , 1979, Mechanisms of Ageing and Development.
[70] K. Åkerman,et al. Changes in membrane potential during calcium ion influx and efflux across the mitochondrial membrane. , 1978, Biochimica et biophysica acta.
[71] R B Setlow,et al. Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species. , 1974, Proceedings of the National Academy of Sciences of the United States of America.
[72] Denham Harman,et al. The Biologic Clock: The Mitochondria? , 1972, Journal of the American Geriatrics Society.
[73] D. Harman. Aging: a theory based on free radical and radiation chemistry. , 1956, Journal of gerontology.
[74] Denham. Harraan. AGING: A THEORY BASED ON FREE RADICAL AND RADIATION CHEMISTRY , 1955 .
[75] N. Clark,et al. Direct Evidence , 1934 .
[76] Z. Ungvari,et al. Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging. , 2007, The American journal of pathology.
[77] L. Liaudet,et al. Nitric oxide and peroxynitrite in health and disease. , 2007, Physiological reviews.
[78] Z. Ungvari,et al. Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging. , 2007, The American journal of pathology.
[79] H. Naito,et al. Age-associated increase in oxidative stress and nuclear factor kappaB activation are attenuated in rat liver by regular exercise. , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[80] R. S. Sohal,et al. Role of oxidative stress in senescence. , 1998, Aging.
[81] A. Salminen,et al. Age-related changes in the regulation of transcription factor NF-kappa B in rat brain. , 1997, Neuroscience letters.
[82] J. Burger,et al. Age- and gender-related variations in the activities of drug-metabolizing and antioxidant enzymes in the white-footed mouse (Peromyscus leucopus). , 1993, Growth, development, and aging : GDA.
[83] J. Burger,et al. Survival and reproduction in Peromyscus leucopus in the laboratory: viable model for aging studies. , 1992, Growth, development, and aging : GDA.
[84] G. Sacher,et al. Longevity, aging and comparative cellular and molecular biology of the house mouse, Mus musculus, and the white-footed mouse, Peromyscus leucopus. , 1978, Birth defects original article series.
[85] R. Nowak,et al. Walker's mammals of the world , 1968 .