Alisertib plus induction chemotherapy in previously untreated patients with high-risk, acute myeloid leukaemia: a single-arm, phase 2 trial.
暂无分享,去创建一个
Traci M. Blonquist | D. Neuberg | T. Graubert | K. Ballen | D. DeAngelo | Jacqueline S. Garcia | D. Steensma | R. Stone | A. Fathi | Yi-Bin Chen | G. Hobbs | Julia E. Foster | A. Brunner | P. Amrein | S. McAfee | T. Blonquist | R. Lindsley | F. Kuo | A. Manning | D. Avigan | J. Rosenblatt | M. Burke | L. Mendez | E. Winer | H. Hock | M. Luskin | Nicole M. Hermance | G. Fell | Meghan K Bergeron | Aura Y. Ramos | Tina T. Som | Kaitlyn M. Fishman | K. McGregor | Christine Connolly | Nicole Nelson | M. McMasters | Emma K. Logan | C. Bertoli | Jenna A. Moran | M. Macrae | Tanya T. Behnan | M. C. Wey | J. Rae | M. Nahas | M. Baltay | Jennifer Lombardi Story | S. Mcafee | Nicole M Hermance | Eric S. Winer | Amity L Manning | Myrna R Nahas | Malgorzata McMasters | Amir T. Fathi | Richard M. Stone | Michele Baltay | R. C. Lindsley | Donna S. Neuberg | D. DeAngelo | Frank C. Kuo | Gabriela S. Hobbs | Jacqueline S Garcia | Andrew M Brunner | Jacqueline S Garcia | Lourdes M Mendez
[1] A. Manning,et al. Aurora A inhibition limits centrosome clustering and promotes mitotic catastrophe in cells with supernumerary centrosomes , 2018, bioRxiv.
[2] Robert K. Stuart,et al. CPX-351 (cytarabine and daunorubicin) Liposome for Injection Versus Conventional Cytarabine Plus Daunorubicin in Older Patients With Newly Diagnosed Secondary Acute Myeloid Leukemia , 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[3] Markus G. Manz,et al. Molecular Minimal Residual Disease in Acute Myeloid Leukemia , 2018, The New England journal of medicine.
[4] Bob Löwenberg,et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. , 2017, Blood.
[5] Traci M. Blonquist,et al. Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia , 2016, Haematologica.
[6] J. Aster,et al. Validation and Implementation of a Custom Next-Generation Sequencing Clinical Assay for Hematologic Malignancies. , 2016, The Journal of molecular diagnostics : JMD.
[7] Mario Cazzola,et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. , 2016, Blood.
[8] D. Neuberg,et al. Acute myeloid leukemia ontogeny is defined by distinct somatic mutations. , 2015, Blood.
[9] A. Rao,et al. Acute myeloid leukemia and myelodysplastic syndromes in older adults. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[10] P. Westervelt,et al. An exploratory phase 2 study of investigational Aurora A kinase inhibitor alisertib (MLN8237) in acute myelogenous leukemia and myelodysplastic syndromes , 2014, Leukemia research reports.
[11] J. Crispino,et al. The Aurora Kinases in Cell Cycle and Leukemia , 2014, Oncogene.
[12] C. Bloomfield,et al. Prognostic significance of the European LeukemiaNet standardized system for reporting cytogenetic and molecular alterations in adults with acute myeloid leukemia. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[13] F. Giles,et al. Targeting Aurora A kinase activity with the investigational agent alisertib increases the efficacy of cytarabine through a FOXO‐dependent mechanism , 2012, International journal of cancer.
[14] K. Venkatakrishnan,et al. Phase I Study of Aurora A Kinase Inhibitor MLN8237 in Advanced Solid Tumors: Safety, Pharmacokinetics, Pharmacodynamics, and Bioavailability of Two Oral Formulations , 2012, Clinical Cancer Research.
[15] J. Baselga,et al. Phase I Pharmacokinetic/Pharmacodynamic Study of MLN8237, an Investigational, Oral, Selective Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors , 2012, Clinical Cancer Research.
[16] F. Giles,et al. Targeting aurora kinases in cancer treatment. , 2011, Current drug targets.
[17] E. Estey,et al. Prediction of early death after induction therapy for newly diagnosed acute myeloid leukemia with pretreatment risk scores: a novel paradigm for treatment assignment. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[18] E. Rego,et al. High expression of AURKA and AURKB is associated with unfavorable cytogenetic abnormalities and high white blood cell count in patients with acute myeloid leukemia. , 2011, Leukemia research.
[19] R. Hills,et al. Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. , 2010, Blood.
[20] H. Döhner,et al. High-dose daunorubicin in older patients with acute myeloid leukemia. , 2009, The New England journal of medicine.
[21] H. Kantarjian,et al. Analysis of Aurora kinase A expression in CD34+ blast cells isolated from patients with myelodysplastic syndromes and acute myeloid leukemia , 2008, Journal of hematopathology.
[22] Qing Jiang,et al. Roles of Aurora Kinases in Mitosis and Tumorigenesis , 2007, Molecular Cancer Research.
[23] B. Cheson,et al. Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. , 2006, Blood.
[24] Eiji Kohmura,et al. Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells* , 2003, Journal of Biological Chemistry.
[25] C. Bloomfield,et al. Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[26] C. Bloomfield,et al. Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). , 2002, Blood.
[27] K Wheatley,et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. , 1998, Blood.
[28] Brown Bw,et al. Confidence limits for probability of response in multistage phase II clinical trials. , 1985 .
[29] N. Nissen,et al. Cytosine arabinoside with daunorubicin or adriamycin for therapy of acute myelocytic leukemia: a CALGB study. , 1982, Blood.
[30] Daniel J Weisdorf,et al. Acute Myeloid Leukemia. , 2015, The New England journal of medicine.