2013 Humaine Association Conference on Affective Computing and Intelligent Interaction, ACII 2013, Geneva, Switzerland, September 2-5, 2013

between Spontaneous Analysis and Modelling of Affective Japanese Sitting Postures by Japanese and British Estimation of Attentiveness of Watching Based on Their Emotional Abstract — With the aim of developing a brain-computer interface for the communication of basic mental states, a classical conditioning paradigm with affective stimuli was used, assessing the possibility to discriminate between affirmative and negative thinking in an fMRI-BCI setting. 6 Alzheimer patients and 7 healthy control subjects participated to the study. Congruent and incongruent word-pairs were respectively associated to pleasant (baby laughter) and unpleasant (scream) affective stimuli. A Support Vector Machine classifier focusing on insula, amygdala and anterior cingulate cortex was used to discriminate between the activations relative to congruent and incongruent word-pairs (eliciting respectively affirmative and negative thinking), following the conditioning process. Classification accuracy was on average 70% for Alzheimer patients, reaching 85%, and on average 69% for control subjects, reaching 83%. This study shows that it is possible to extract information on individuals’ mental states by exploiting affective responses, overcoming the typical obstacles of traditional BCIs, which generally require time-consuming trainings and intact cognition.

[1]  Niels Birbaumer,et al.  Real-time support vector classification and feedback of multiple emotional brain states , 2011, NeuroImage.

[2]  B. Desgranges,et al.  When the zebra loses its stripes: Semantic priming in early Alzheimer's disease and semantic dementia , 2011, Cortex.

[3]  D. Selkoe Alzheimer's disease. , 2011, Cold Spring Harbor perspectives in biology.

[4]  Stefan Carmien,et al.  Affective brain-computer interfaces: Psychophysiological markers of emotion in healthy persons and in persons with amyotrophic lateral sclerosis , 2009, 2009 3rd International Conference on Affective Computing and Intelligent Interaction and Workshops.

[5]  Vanessa Taler,et al.  Language performance in Alzheimer's disease and mild cognitive impairment: A comparative review , 2008, Journal of clinical and experimental neuropsychology.

[6]  Rhonda B. Friedman,et al.  The underlying mechanisms of semantic memory loss in Alzheimer's disease and semantic dementia , 2008, Neuropsychologia.

[7]  Cuntai Guan,et al.  Temporal classification of multichannel near-infrared spectroscopy signals of motor imagery for developing a brain–computer interface , 2007, NeuroImage.

[8]  Rainer Goebel,et al.  Information-based functional brain mapping. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[9]  Ellen Winner,et al.  Inference of beliefs and emotions in patients with Alzheimer's disease. , 2006, Neuropsychology.

[10]  K. Luan Phan,et al.  Functional Neuroanatomy of Emotion: A Meta-Analysis of Emotion Activation Studies in PET and fMRI , 2002, NeuroImage.

[11]  G J Acton,et al.  Communication from individuals with advanced DAT: can it provide clues to their sense of self-awareness and well-being? , 2001, Geriatric nursing.

[12]  J. Montepare,et al.  Emotion processing in the visual and auditory domains by patients with Alzheimer's disease , 1999, Journal of the International Neuropsychological Society.

[13]  R. Nebes,et al.  Contextual facilitation of lexical processing in Alzheimer's disease: intralexical priming or sentence-level priming? , 1994, Journal of clinical and experimental neuropsychology.

[14]  Marilyn Hartman,et al.  The use of semantic knowledge in Alzheimer's disease: Evidence for impairments of attention , 1991, Neuropsychologia.

[15]  E. Miller,et al.  Language impairment in Alzheimer type dementia , 1989 .

[16]  Loraine K. Obler,et al.  The relation of aphasia to dementia , 1988 .