Panhypopituitarism caused by solitary parasellar metastasis from lung cancer.

Clinical panhypopituitarism caused by cancer with parasellar metastasis and hypothalamic invasion is very rare. This report concerns a lung cancer patient who had solitary parasellar metastasis with diabetes insipidus and panhypopituitarism as an initial manifestation, which was documented by contrast-enhanced computed tomographic scan, Gd-DTPA-enhanced magnetic resonance imaging, and endocrinologic studies.

[1]  R. Sands,et al.  Low dose ondansetron and dexamethasone: a cost effective alternative to high dose metoclopramide/dexamethasone/lorazepam in the prevention of acute cisplatin induced emesis. , 1992, Clinical oncology (Royal College of Radiologists (Great Britain)).

[2]  A. Powell,et al.  Infundibular metastasis and panhypopituitarism. , 1989, Journal of the National Medical Association.

[3]  E. Laws,et al.  Metastatic tumors of the sella turcica masquerading as primary pituitary tumors. , 1987, The Journal of clinical endocrinology and metabolism.

[4]  J. Hainsworth,et al.  The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in small-cell lung cancer. , 1986, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[5]  L. H. Maurer Ectopic hormone syndromes in small cell carcinoma of the lung , 1985 .

[6]  J. Mockel,et al.  Diabetes insipidus from metastatic oat cell carcinoma: recovery after brain irradiation. , 1985, The American journal of the medical sciences.

[7]  M. Ferdeghini,et al.  Intrasellar metastasis mimicking a pituitary adenoma. , 1983, Surgical neurology.

[8]  D. Rottenberg,et al.  Pituitary metastasis , 1981, Neurology.

[9]  W. Bauman,et al.  Adrenal failure associated with hypothalamic and adrenal metastases: A case report and review of the literature , 1981 .

[10]  B. Zinman,et al.  Hyperprolactinemia, hypopituitarism, and chiasmal compression due to carcinoma metastatic to the pituitary. , 1981, Neurosurgery.

[11]  J. Minna,et al.  CNS metastases in small cell bronchogenic carcinoma. Increasing frequency and changing pattern with lengthening survival , 1979, Cancer.

[12]  R. Teears,et al.  Clinicopathologic review of 88 cases of carcinoma metastatic to the pituitary gland , 1975, Cancer.

[13]  R. Yalow,et al.  Ectopic ACTH production in carcinoma of the lung. , 1974, The Journal of clinical investigation.

[14]  P. Goldswain,et al.  Pituitary insufficiency, inappropriate antidiuretic hormone (ADH) secretion, and carcinoma of the bronchus , 1973, Cancer.

[15]  K. Kovacs,et al.  Metastatic cancer of the pituitary gland. , 1973, Oncology.

[16]  J. Horton,et al.  Clinical features of tumor metastasis to the pituitary , 1970, Cancer.

[17]  L. Duchen Metastatic carcinoma in the pituitary gland and hypothalamus. , 1966, The Journal of pathology and bacteriology.