Estudo macroscópico das aderências peritoneais provocadas experimentalmente em cães

This research was performed in order to study the adhesion formation induced by injury to the peritoneum at the time of surgery. In the present study ischemia by ligation appears to be the most potent adhesiogenic factor. Serosal injury and drying and the lesions cauterized by electric cautery were forms of serosal injury that induced fibrinous or irreversible adhesions. Adhesions were stimulated when drying was combined with rubbing the tissue with dry gauze. The combinant drying with fibrin enhanced the inicial adhesion. Comparing the four factors, serosal injury was posibly the least likely to cause adhesions. In this type of injury the fibrinolitic mechanism was not inhibited.

[1]  J. Langer,et al.  Role of mast cells in peritoneal adhesion formation. , 1993, American journal of surgery.

[2]  R. Williams,et al.  Effect of transforming growth factor beta on postoperative adhesion formation and intact peritoneum. , 1992, The Journal of surgical research.

[3]  E. Baracat,et al.  [Heparin effect on prevention of pelvic adhesions. Experimental study]. , 1991, Revista paulista de medicina.

[4]  B. Ahrén,et al.  Phosphatidylcholine prevents postoperative peritoneal adhesions: an experimental study in the rat. , 1991, The Journal of surgical research.

[5]  R. Veldhuizen,et al.  Prevention of postoperative adhesions by tissue-type plasminogen activator (t-PA) in the rabbit. , 1990, European journal of obstetrics, gynecology, and reproductive biology.

[6]  L. Spitz,et al.  The prevention of post-operative adhesions using a gastrointestinal prokinetic agent. , 1989, Journal of pediatric surgery.

[7]  O. Kotoulas,et al.  The role of oxygen-derived free radicals in peritoneal adhesion formation induced by ileal ischaemia/reperfusion. , 1989, Acta chirurgica Scandinavica.

[8]  M. Kurzer,et al.  Indomethacin decreases carrageenan-induced peritoneal adhesions. , 1988, Surgery.

[9]  T. Kissel,et al.  Prevention of peritoneal adhesions in the rat with sustained intraperitoneal dexamethasone delivered by a novel therapeutic system. , 1987, Annales chirurgiae et gynaecologiae.

[10]  D. Slatter.  Textbook of small animal surgery , 1985 .

[11]  E. Wallach,et al.  Prevention and management of peritoneal adhesions. , 1984, Fertility and sterility.

[12]  A. Rivkind,et al.  Cianidanol ( [+]-cyanidanol-3) prevents the development of abdominal adhesions in rats. , 1983, Archives of surgery.

[13]  B. M. Cohen,et al.  Use of intraperitoneal solutions for preventing pelvic adhesions in the rat. , 1983, The Journal of reproductive medicine.

[14]  G. Chalkiadakis,et al.  The effect of heparin upon fibrinopurulent peritonitis in rats. , 1983, Surgery, gynecology & obstetrics.

[15]  A. Raftery.  Effect of peritoneal trauma on peritoneal fibrinolytic activity and intraperitoneal adhesion formation. An experimental study in the rat. , 1981, European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes.

[16]  R. Winston.  REVERSAL OF TUBAL STERILIZATION , 1980, The Medical journal of Australia.

[17]  D. Milligan,et al.  Observations on the pathogenesis of peritoneal adhesions: a light and electron microscopical study , 1974, The British journal of surgery.

[18]  D. Silver,et al.  Serosal hypofibrinolysis. A cause of postoperative adhesions. , 1973, American journal of surgery.

[19]  H. Ellis,et al.  The aetiology of post‐operative abdominal adhesions an experimental study , 1962, The British journal of surgery.

[20]  Moore Rm,et al.  Failure of reperitonealization to prevent abdominal adhesions in the dog. , 1952 .

[21]  R. M. Moore,et al.  Failure of reperitonealization to prevent abdominal adhesions in the dog. , 1952, The American surgeon.