Immune response, glucose metabolism, and performance of stressed feeder calves fed inorganic or organic chromium.

One hundred twenty-five Angus crossbred steers (215 +/- 2 kg initial BW) were blocked by weight and assigned to pens. Pens were randomly assigned to treatment (six pens/treatment). Treatments consisted of 1) control (no supplemental Cr), 2) CrCl3, 3) high-Cr yeast, or 4) Cr nicotinic acid complex. Chromium was added to provide .4 mg of supplemental Cr/kg of DM. Steers were fed diets containing 90% corn silage (DM basis) and 10% soybean meal-mineral-vitamin supplement. Steers were allowed to consume the diets on an ad libitum basis during the 56-d study. Performance was not affected by treatment. On d 52, steers supplemented with high-Cr yeast had a greater response to an intradermal injection of phytohemagglutin (PHA) for 8 h after injection than control steers (P < .10) or those supplemented with CrCl3 (P < .05) or Cr nicotinic acid (P < .05). Peripheral lymphocytes from steers supplemented with Cr nicotinic acid had a greater (P < .05) blastogenic response to 12.5 micrograms PHA/mL than lymphocytes from steers supplemented with CrCl3. After an i.v. infusion of glucose (.25 g of glucose/kg BW), plasma glucose tended (P < .11) to decrease at a faster rate from 15 to 45 min after infusion in steers fed Cr nicotinic acid. Steers supplemented with Cr nicotinic acid had greater (P < .05) serum insulin 15 and 30 min after infusion than those supplemented with CrCl3 and high-Cr yeast. Controls had lower serum insulin than those supplemented with Cr nicotinic acid 30 min after infusion.(ABSTRACT TRUNCATED AT 250 WORDS)

[1]  D. Thompson,et al.  Influence of chromium picolinate on glucose usage and metabolic criteria in growing Holstein calves. , 1994, Journal of animal science.

[2]  E. Kegley,et al.  Effect of copper level and source (copper lysine vs copper sulfate) on copper status, performance, and immune response in growing steers fed diets with or without supplemental molybdenum and sulfur. , 1993, Journal of animal science.

[3]  R. Yancey Recent advances in bovine vaccine technology. , 1993, Journal of dairy science.

[4]  W. Yang,et al.  Chelated chromium for stressed feeder calves , 1993 .

[5]  D. Mowat,et al.  Effect of level of supplemental chromium on performance, serum constituents, and immune status of stressed feeder calves. , 1993, Journal of animal science.

[6]  X. Chang,et al.  Supplemental chromium for stressed and growing feeder calves. , 1992, Journal of animal science.

[7]  T. Weekes Hormonal Control of Glucose Metabolism , 1991 .

[8]  津田 恒之,et al.  Physiological aspects of digestion and metabolism in ruminants : proceedings of the Seventh International Symposium on Ruminant Physiology , 1991 .

[9]  S. Loerch,et al.  Effects of parenteral selenium and vitamin E on performance, health and humoral immune response of steers new to the feedlot environment. , 1989, Journal of animal science.

[10]  K. Kelley,et al.  Cross-talk between the immune and endocrine systems. , 1988, Journal of animal science.

[11]  S. Goyal,et al.  Immunosuppression in animals. , 1988, The British veterinary journal.

[12]  P. Deuster,et al.  Exercise effects on chromium excretion of trained and untrained men consuming a constant diet. , 1988, Journal of applied physiology.

[13]  M. Taylor,et al.  Studies of immune function of CD-1 mice exposed to aflatoxin B1. , 1987, Toxicology.

[14]  R. P. Brockman Pancreatic and adrenal hormonal regulation of metabolism , 1986 .

[15]  E. Rayfield,et al.  Relationship Between Serum Chromium Concentrations and Glucose Utilization in Normal and Infected Subjects , 1975, Diabetes.

[16]  W Mertz,et al.  Chromium occurrence and function in biological systems. , 1969, Physiological reviews.

[17]  P. J. Randle,et al.  Immunoassay of insulin with insulin antibody preciptate. , 1963, Lancet.

[18]  J. Kaneko Clinical biochemistry of domestic animals , 1963 .

[19]  B. Vallee,et al.  Nucleic Acids and Metals I. CHROMIUM, MANGANESE, NICKEL, IRON, AND OTHER METALS IN RIBONUCLEIC ACID FROM DIVERSE BIOLOGICAL SOURCES , 1959 .