Did the PREDIMED trial test a Mediterranean diet?

The U.S. Dietary Guidelines recommend healthy dietary patterns — specifically, the Dietary Approaches to Stop Hypertension (DASH) diet and Mediterranean-style diets.1 A persuasive body of evidence from observational studies has documented that Mediterranean-style diets are associated with a substantially reduced risk of cardiovascular disease.2 Mediterranean diets are not a single dietary pattern, but they do have common features — an emphasis on vegetables, fruits, beans, nuts, seeds, breads, unrefined grains, and olive oil (but not necessarily extra-virgin olive oil); inclusion of fish and wine; and minimal intake of meats and full-fat dairy products.3 Such diets are rich in total, monounsaturated, . . .

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[4]  P. Barberger‐Gateau,et al.  Olive oil consumption, plasma oleic acid, and stroke incidence , 2011, Neurology.

[5]  Rosanna Abbate,et al.  Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis. , 2010, The American journal of clinical nutrition.

[6]  G. Guyatt,et al.  Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. , 2010, JAMA.

[7]  Dolores Corella,et al.  Effects of a Mediterranean-Style Diet on Cardiovascular Risk Factors , 2006, Annals of Internal Medicine.

[8]  B V Howard,et al.  AHA Science Advisory: Lyon Diet Heart Study. Benefits of a Mediterranean-style, National Cholesterol Education Program/American Heart Association Step I Dietary Pattern on Cardiovascular Disease. , 2001, Circulation.

[9]  M. de Lorgeril,et al.  Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. , 1999, Circulation.

[10]  Jean-Louis Martin,et al.  Mediterranean Diet, Traditional Risk Factors, and the Rate of Cardiovascular Complications After Myocardial Infarction Final Report of the Lyon Diet Heart Study , 1999 .