Bis-aryloxadiazoles as effective activators of the aryl hydrocarbon receptor.

[1]  D. Shelton,et al.  Chemical Genetic Screen Reveals a Role for Desmosomal Adhesion in Mammary Branching Morphogenesis , 2012, The Journal of Biological Chemistry.

[2]  Annalisa Bordogna,et al.  New Aryl Hydrocarbon Receptor Homology Model Targeted To Improve Docking Reliability , 2011, J. Chem. Inf. Model..

[3]  R. Somani,et al.  Synthesis and Evaluation of Antiinflammatory, Analgesic and Ulcerogenic Potential of NSAIDs Bearing 1,3,4-Oxadiazole Scaffold , 2011, Indian journal of pharmaceutical sciences.

[4]  B. Lawrence,et al.  Activation of the Aryl Hydrocarbon Receptor During Pregnancy in the Mouse Alters Mammary Development Through Direct Effects on Stromal and Epithelial Tissues1 , 2011, Biology of reproduction.

[5]  Matthew E Welsch,et al.  Privileged scaffolds for library design and drug discovery. , 2010, Current opinion in chemical biology.

[6]  F. Whelan,et al.  The pleiotropy of dioxin toxicity--xenobiotic misappropriation of the aryl hydrocarbon receptor's alternative physiological roles. , 2009, Pharmacology & therapeutics.

[7]  A. Pace,et al.  The new era of 1,2,4-oxadiazoles. , 2009, Organic & biomolecular chemistry.

[8]  Lorenz M Mayr,et al.  Novel trends in high-throughput screening. , 2009, Current opinion in pharmacology.

[9]  B. Lawrence,et al.  TCDD exposure disrupts mammary epithelial cell differentiation and function. , 2009, Reproductive toxicology.

[10]  K. Shah,et al.  Synthesis and anticancer activities of novel 3,5-disubstituted-1,2,4-oxadiazoles. , 2009, Bioorganic & medicinal chemistry letters.

[11]  D. Hazuda,et al.  Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection. , 2008, Journal of medicinal chemistry.

[12]  D. Garrod,et al.  Desmosome structure, composition and function. , 2008, Biochimica et biophysica acta.

[13]  Meenal Patel,et al.  PTC124 targets genetic disorders caused by nonsense mutations , 2007, Nature.

[14]  P. Boutros,et al.  Aryl Hydrocarbon Receptor Regulates Distinct Dioxin-Dependent and Dioxin-Independent Gene Batteries , 2006, Molecular Pharmacology.

[15]  S. A. Parent,et al.  Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3. , 2005, Journal of medicinal chemistry.

[16]  L. Qiu,et al.  Discovery and structure-activity relationship of 3-aryl-5-aryl-1,2,4-oxadiazoles as a new series of apoptosis inducers and potential anticancer agents. , 2005, Journal of medicinal chemistry.

[17]  P. Mandal Dioxin: a review of its environmental effects and its aryl hydrocarbon receptor biology , 2005, Journal of Comparative Physiology B.

[18]  N. Cosford,et al.  Discovery of novel heteroarylazoles that are metabotropic glutamate subtype 5 receptor antagonists with anxiolytic activity. , 2004, Journal of medicinal chemistry.

[19]  Jennifer A Cundiff,et al.  A novel effect of dioxin: exposure during pregnancy severely impairs mammary gland differentiation. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.

[20]  J. Whitlock,et al.  Induction of cytochrome P4501A1. , 1999, Annual review of pharmacology and toxicology.