MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation
暂无分享,去创建一个
K. Ohuchida | N. Sato | K. Mizumoto | Masao Tanaka | Jun Yu | H. Fujita | Tadashi Kayashima | K. Nakata | Kouhei Nakata
[1] E. Howe,et al. Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers , 2009, Journal of oncology.
[2] Norbert Senninger,et al. EP300—A miRNA‐regulated metastasis suppressor gene in ductal adenocarcinomas of the pancreas , 2010, International journal of cancer.
[3] Zhiwei Wang,et al. Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. , 2009, Cancer research.
[4] Michael F. Clarke,et al. Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells , 2009, Cell.
[5] D. Saur,et al. E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex. , 2009, Gastroenterology.
[6] G. Hurteau,et al. Stable expression of miR-200c alone is sufficient to regulate TCF8 (ZEB1) and restore E-cadherin expression , 2009, Cell cycle.
[7] S. Nordeen,et al. MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents , 2009, Molecular Cancer Therapeutics.
[8] C. Langmead,et al. ANGIOPOIETIN-2, A REGULATOR OF VASCULAR PERMEABILITY IN INFLAMMATION IS ELEVATED IN SEVERE ACUTE PANCREATITIS AND IS ASSOCIATED WITH SYSTEMIC ORGAN FAILURE , 2008 .
[9] K. Ohuchida,et al. LIM only 4 is overexpressed in late stage pancreas cancer , 2008, Molecular Cancer.
[10] Daniel B. Martin,et al. Circulating microRNAs as stable blood-based markers for cancer detection , 2008, Proceedings of the National Academy of Sciences.
[11] X. Wang,et al. E-cadherin upregulation as a therapeutic goal in cancer treatment. , 2008, Mini reviews in medicinal chemistry.
[12] Sun-Mi Park,et al. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. , 2008, Genes & development.
[13] H. Höfler,et al. The E-cadherin repressor Snail is associated with lower overall survival of ovarian cancer patients , 2007, British Journal of Cancer.
[14] Sam W. Lee,et al. Membrane-bound heparin-binding epidermal growth factor like growth factor regulates E-cadherin expression in pancreatic carcinoma cells. , 2007, Cancer research.
[15] S. Spivack,et al. Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin. , 2007, Cancer research.
[16] George A Calin,et al. Chromosomal rearrangements and microRNAs: a new cancer link with clinical implications. , 2007, The Journal of clinical investigation.
[17] G. Lutz,et al. Nanopolymers improve delivery of exon skipping oligonucleotides and concomitant dystrophin expression in skeletal muscle of mdx mice , 2008, BMC biotechnology.
[18] Celeste M. Nelson,et al. E-cadherin engagement stimulates proliferation via Rac1 , 2006, The Journal of cell biology.
[19] Kenoki Ohuchida,et al. The Role of S100A6 in Pancreatic Cancer Development and Its Clinical Implication as a Diagnostic Marker and Therapeutic Target , 2005, Clinical Cancer Research.
[20] S. Lowe,et al. A microRNA polycistron as a potential human oncogene , 2005, Nature.
[21] F. Slack,et al. RAS Is Regulated by the let-7 MicroRNA Family , 2005, Cell.
[22] K. Ohuchida,et al. Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions. , 2004, Cancer research.
[23] F. Motoi,et al. Pancreatic Cancer Registry in Japan: 20 Years of Experience , 2004, Pancreas.
[24] D. Bartel. MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.
[25] Michael Z Michael,et al. Reduced accumulation of specific microRNAs in colorectal neoplasia. , 2003, Molecular cancer research : MCR.
[26] S. Hamilton-Dutoit,et al. Towards quantitative mRNA analysis in paraffin-embedded tissues using real-time reverse transcriptase-polymerase chain reaction: a methodological study on lymph nodes from melanoma patients. , 2003, The Journal of molecular diagnostics : JMD.
[27] C. Croce,et al. Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[28] K. Hirata,et al. Telomerase activity of cultured human pancreatic carcinoma cell lines correlates with their potential for migration and invasion , 2001, Cancer.
[29] A. Nakao,et al. PGP9.5 as a prognostic factor in pancreatic cancer. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[30] T. Godfrey,et al. Quantitative mRNA expression analysis from formalin-fixed, paraffin-embedded tissues using 5' nuclease quantitative reverse transcription-polymerase chain reaction. , 2000, The Journal of molecular diagnostics : JMD.
[31] H. Niiyama,et al. Quantitative determination of apoptotic death in cultured human pancreatic cancer cells by propidium iodide and digitonin. , 1999, Cancer letters.
[32] L. Ellis,et al. Relative expression of E-cadherin and type IV collagenase genes predicts disease outcome in patients with resectable pancreatic carcinoma. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.
[33] Masahiro Yamamoto,et al. Japan Pancreatic Cancer Registry: current status. , 1998, Pancreas.
[34] R. Hruban,et al. Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma , 1994, Nature Genetics.
[35] H. Höfler,et al. E-cadherin gene mutations provide clues to diffuse type gastric carcinomas. , 1994, Cancer research.
[36] P. Musiani,et al. Inhibition of tumor growth and enhancement of metastasis after transfection of the γ‐interferon gene , 1993 .
[37] G. Gores,et al. A novel cytotoxicity screening assay using a multiwell fluorescence scanner. , 1992, Toxicology and applied pharmacology.
[38] W. Fiers,et al. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role , 1991, Cell.
[39] D. Shibata,et al. Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes , 1988, Cell.