The utility of frozen-section diagnosis with cervical conization before planned hysterectomy

Frozen-section evaluations of cervical cone biopsy specimens were performed at the time of planned hysterectomy to exclude invasive cervical cancer. During a 10-year period, we evaluated 30 cone biopsy specimens by frozen section. We found all the diagnoses made with frozen sections to be accurate when compared with permanent sections, and all patients received appropriate therapy. Twenty-nine cases showed no evidence of invasion. One patient had invasive cervical cancer diagnosed on frozen section and confirmed with permanent sections. When hysterectomy is immediately followed by conization, no complications occurred and no significant increase in blood loss was noted. We found frozen-section evaluation of a cone biopsy specimen at the time of planned hysterectomy to be a reliable procedure that saves time, eliminates the risk of additional anesthesia, and decreases patients' cost.

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