Is the Modified Early Warning Score (MEWS) superior to clinician judgement in detecting critical illness in the pre-hospital environment?

AIM Physiological track and trigger scores have an established role in enhancing the detection of critical illness in hospitalized patients. Their potential to identify individuals at risk of clinical deterioration in the pre-hospital environment is unknown. This study compared the predictive accuracy of the Modified Early Warning Score (MEWS) with current clinical practice. METHODS A retrospective observational cohort study of consecutive adult (≥16 yrs) emergency department attendances to a single centre over a two-month period. The outcome of interest was the occurrence or not of an adverse event within 24h of admission. Hospital pre-alerting was used as a measure of current critical illness detection and its accuracy compared with MEWS scores calculated from pre-hospital observations. RESULTS 3504 patients were included in the study. 76 (2.5%) suffered an adverse event within 24 h of admission. Paramedics pre-alerted the hospital in 224 cases (7.3%). Clinical judgement demonstrated a sensitivity of 61.8% (95% CI 51.0-72.8%) with a specificity of 94.1% (95% CI 93.2-94.9%). MEWS was a good predictor of adverse outcomes and hence critical illness detection (AUC 0.799, 95% CI 0.738-0.856). Combination systems of MEWS and clinical judgement may be effective MEWS ≥4+clinical judgement: sensitivity 72.4% (95% CI 62.5-82.7%), specificity 84.8% (95% CI 83.52-86.1%). CONCLUSIONS Clinical judgement alone has a low sensitivity for critical illness in the pre-hospital environment. The addition of MEWS improves detection at the expense of reduced specificity. The optimal scoring system to be employed in this setting is yet to be elucidated.

[1]  L. Wallis,et al.  A prospective evaluation of the Cape triage score in the emergency department of an urban public hospital in South Africa , 2008, Emergency Medicine Journal.

[2]  Tom Hughes-Davies,et al.  Hospital volume and outcomes of mechanical ventilation. , 2006, The New England journal of medicine.

[3]  C. Subbe,et al.  Validation of physiological scoring systems in the accident and emergency department , 2006, Emergency Medicine Journal.

[4]  Kirsty Challen,et al.  Physiological Scoring: An Aid to Emergency Medical Services Transport Decisions? , 2010, Prehospital and Disaster Medicine.

[5]  J. Gardner-Thorpe,et al.  The value of Modified Early Warning Score (MEWS) in surgical in-patients: a prospective observational study. , 2006, Annals of the Royal College of Surgeons of England.

[6]  T J Coats,et al.  Prediction of mortality in adult emergency department patients with sepsis , 2009, Emergency Medicine Journal.

[7]  M. Hubble,et al.  Paramedic Determinations of Medical Necessity: A Meta-Analysis , 2009, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

[8]  W. N. Venables,et al.  An introduction to R : a programming environment for data analysis and graphics , 2009 .

[9]  S. Goodacre,et al.  Predictive scoring in non-trauma emergency patients: a scoping review , 2011, Emergency Medicine Journal.

[10]  J Nicholl,et al.  Prediction of mortality among emergency medical admissions , 2006, Emergency Medicine Journal.

[11]  Munish Goyal,et al.  Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department* , 2010, Critical care medicine.

[12]  L. Brown,et al.  Effect of vital signs on advanced life support interventions for prehospital patients. , 1997, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

[13]  B. Gabbe,et al.  Is paramedic judgement useful in prehospital trauma triage? , 2005, Injury.

[14]  C. Levi,et al.  The Rural Prehospital Acute Stroke Triage (PAST) Trial Protocol: A Controlled Trial for Rapid Facilitated Transport of Rural Acute Stroke Patients to a Regional Stroke Centre , 2010, International journal of stroke : official journal of the International Stroke Society.

[15]  S. Kronick,et al.  Recommended guidelines for monitoring, reporting, and conducting research on medical emergency team, outreach, and rapid response systems: an Utstein-style scientific statement. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency , 2007, Resuscitation.

[16]  C.J.H. Mann,et al.  Clinical Prediction Models: A Practical Approach to Development, Validation and Updating , 2009 .

[17]  C. Subbe,et al.  Does earlier detection of critically ill patients on surgical wards lead to better outcomes? , 2005, Annals of the Royal College of Surgeons of England.

[18]  J. Ottervanger,et al.  Prehospital triage in the ambulance reduces infarct size and improves clinical outcome. , 2011, American heart journal.

[19]  Paul E. Schmidt,et al.  Review and performance evaluation of aggregate weighted 'track and trigger' systems. , 2008, Resuscitation.

[20]  John Tercier,et al.  Resuscitation , 2004, The Lancet.

[21]  A. Bleetman,et al.  Ambulance alerting to hospital: the need for clearer guidance , 2006, Emergency Medicine Journal.

[22]  Gary B. Smith,et al.  ViEWS--Towards a national early warning score for detecting adult inpatient deterioration. , 2010, Resuscitation.

[23]  Brian H Cuthbertson,et al.  Optimising early warning scoring systems. , 2008, Resuscitation.

[24]  B. Cuthbertson,et al.  Detecting critical illness outside the ICU: the role of track and trigger systems , 2010, Current opinion in critical care.

[25]  Saba Sarwar,et al.  National Confidential Enquiry into Patient Outcome and Death , 2007 .

[26]  D. Harrison,et al.  Systematic review and evaluation of physiological track and trigger warning systems for identifying at-risk patients on the ward , 2007, Intensive Care Medicine.

[27]  T. Rea,et al.  Prediction of critical illness during out-of-hospital emergency care. , 2010, JAMA.

[28]  R. Morgan,et al.  An early warning scoring system for detecting developing critical illness , 1997 .

[29]  V. Burch,et al.  Modified early warning score predicts the need for hospital admission and inhospital mortality , 2008, Emergency Medicine Journal.

[30]  C. Subbe,et al.  Validation of a modified Early Warning Score in medical admissions. , 2001, QJM : monthly journal of the Association of Physicians.

[31]  R. Brown,et al.  Blue calls—time for a change? , 2001, Emergency medicine journal : EMJ.

[32]  Nicole A. Lazar,et al.  Statistical Analysis With Missing Data , 2003, Technometrics.

[33]  P. Myles,et al.  Outcome of emergency department patients with delayed admission to an intensive care unit. , 2002, Emergency medicine.

[34]  Giles Morgan,et al.  Confidential inquiry into quality of care before admission to intensive care , 1998, BMJ.

[35]  J. Groarke,et al.  Use of an admission early warning score to predict patient morbidity and mortality and treatment success , 2008, Emergency Medicine Journal.