Transplantation of kidneys from living related donors: Comparison with cadaveric kidney transplantation

In a series of 271 transplantations of renal allografts, performed over 10 years, the rates of graft survival, patient survival, and morbidity in the recipients of allografts from living related donors (47 allografts) have been compared with those in the recipients of cadaveric allografts (224 allografts). The one‐year graft survival rates were 88% for allografts from living related donors (100%, if these were HLA‐identical) and 55% for cadaveric allografts, while the patient survival rates were 97% and 87%, respectively, in the same period. Morbidity rates (expressed as the number of days spent in hospital) for recipients of allografts from living related donors were approximately 50% of those for recipients of cadaveric grafts. Complications in the living related donors were minimal, and acceptable. It is concluded that transplantation of allografts from living related donors has many advantages over transplantation of cadaveric kidneys, and is a valuable adjunct to a cadaveric renal transplantation programme. Greater use of living related kidney donors should be encouraged in Australia.

[1]  F. Brunner,et al.  Combined report on regular dialysis and transplantation in Europe, XI, 1980. , 1981, Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association.

[2]  R. Atkins,et al.  Living related renal transplantation: experience in 22 cases. , 1979, The Australian and New Zealand journal of surgery.

[3]  F. Brunner,et al.  Combined report on regular dialysis and transplantation of children in Europe, 1977. , 1978, Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association.

[4]  The 13th report of the human renal transplant registry. , 1977, Transplantation proceedings.

[5]  M. Mcloughlin Related living donor nephrectomy. , 1976, The Journal of urology.

[6]  J. H. Harrison,et al.  Experience with living familial renal donors. , 1974, Surgery, gynecology & obstetrics.

[7]  M. Smith,et al.  Living kidney donors. , 1973, The Journal of urology.

[8]  K. Schärer,et al.  Combined report on regular dialysis and transplantation in Europe, 3, 1972. , 1973, Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association.

[9]  R. Lord,et al.  RENAL TRANSPLANTATION IN SOUTH AUSTRALIA , 1972, The Medical journal of Australia.

[10]  R. B. Smith,et al.  Operative morbidity among 40 living kidney donors. , 1972, The Journal of surgical research.

[11]  T. Starzl,et al.  Use of living donors in kidney transplantation in man. , 1970, Archives of surgery.

[12]  J. Holmes,et al.  Renal function in 29 healthy adults before and after nephrectomy. , 1966, JAMA.

[13]  F. Ederer,et al.  Maximum utilization of the life table method in analyzing survival. , 1958, Journal of chronic diseases.