Establishment and Characterization of an In Vitro Model of Fas-Mediated Hepatocyte Cell Death.

[1]  T. Vanhaecke,et al.  Characterization of spontaneous cell death in monolayer cultures of primary hepatocytes , 2011, Archives of Toxicology.

[2]  T. Vanhaecke,et al.  Biochemical Characterisation of an In Vitro Model of Hepatocellular Apoptotic Cell Death , 2009, Alternatives to laboratory animals : ATLA.

[3]  G. Ladurner,et al.  Ferritin and FasL (CD95L) mediate density dependent apoptosis in primary rat hepatocytes , 2008, Journal of cellular physiology.

[4]  Xiao-yong Lei,et al.  siRNA‐MEDIATED BCL‐2 AND BCL‐XL GENE SILENCING SENSITIZES HUMAN HEPATOBLASTOMA CELLS TO CHEMOTHERAPEUTIC DRUGS , 2007, Clinical and experimental pharmacology & physiology.

[5]  U. Hopt,et al.  Hepatocyte proliferation and apoptosis in rat liver after liver injury. , 2006, Hepato-gastroenterology.

[6]  Vera Rogiers,et al.  Involvement of Cell Junctions in Hepatocyte Culture Functionality , 2006, Critical reviews in toxicology.

[7]  T. Vanhaecke,et al.  Isolation of rat hepatocytes. , 2006, Methods in molecular biology.

[8]  T. Vanhaecke,et al.  Hepatocyte cultures in drug metabolism and toxicological research and testing. , 2006, Methods in molecular biology.

[9]  G. Gores,et al.  Bid is upstream of lysosome-mediated caspase 2 activation in tumor necrosis factor alpha-induced hepatocyte apoptosis. , 2005, Gastroenterology.

[10]  G. Wiederschain.  Essentials of apoptosis. A guide for basic and clinical research , 2005, Biochemistry (Moscow).

[11]  Honglin Li,et al.  Hypothermia Inhibits Fas-Mediated Apoptosis of Primary Mouse Hepatocytes in Culture , 2004, Cell transplantation.

[12]  Min Zhang,et al.  Inhibition of mouse hepatocyte apoptosis via anti-Fas ribozyme. , 2004, World journal of gastroenterology.

[13]  T. Vanhaecke,et al.  Effect of the histone deacetylase inhibitor trichostatin A on spontaneous apoptosis in various types of adult rat hepatocyte cultures. , 2004, Biochemical pharmacology.

[14]  S. Daburon,et al.  Cutting Edge: SDS-Stable Fas Microaggregates: An Early Event of Fas Activation Occurring with Agonistic Anti-Fas Antibody but Not with Fas Ligand 1 , 2003, The Journal of Immunology.

[15]  C. Ethier,et al.  Antiapoptotic effect of EGF on mouse hepatocytes associated with downregulation of proapoptotic Bid protein. , 2003, American journal of physiology. Gastrointestinal and liver physiology.

[16]  H. Friess,et al.  Primary human hepatocytes--a valuable tool for investigation of apoptosis and hepatitis B virus infection. , 2003, Journal of hepatology.

[17]  Xiao-Ming Yin,et al.  Essentials of Apoptosis , 2003, Humana Press.

[18]  J. Gugenheim,et al.  Spontaneous apoptosis in primary cultures of human and rat hepatocytes: molecular mechanisms and regulation by dexamethasone , 2002, Cell Death and Differentiation.

[19]  J. Boyer,et al.  Ursodeoxycholic acid diminishes Fas‐ligand–induced apoptosis in mouse hepatocytes , 2002, Hepatology.

[20]  G. Gores,et al.  Mechanisms of hepatotoxicity. , 2002, Toxicological sciences : an official journal of the Society of Toxicology.

[21]  J. Castell,et al.  Sensitive markers used to identify compounds that trigger apoptosis in cultured hepatocytes. , 2002, Toxicological sciences : an official journal of the Society of Toxicology.

[22]  J. Gugenheim,et al.  Dexamethasone inhibits spontaneous apoptosis in primary cultures of human and rat hepatocytes via Bcl-2 and Bcl-xL induction , 2001, Cell Death and Differentiation.

[23]  L. Schwartz,et al.  Model cell lines for the study of apoptosis in vitro. , 2001, Methods in cell biology.

[24]  K. Okada,et al.  Apoptosis and cell proliferation in rat hepatocytes induced by barbiturates. , 2000, The Journal of veterinary medical science.

[25]  S. Maeda.  Mechanisms of active cell death in isolated hepatocytes , 2000 .

[26]  G. Farrell,et al.  The effects of cell density, attachment substratum and dexamethasone on spontaneous apoptosis of rat hepatocytes in primary culture , 1999, In Vitro Cellular & Developmental Biology - Animal.

[27]  G. Cohen,et al.  Apoptosis and necrosis in toxicology: a continuum or distinct modes of cell death? , 1997, Pharmacology & therapeutics.

[28]  J. Russell,et al.  Agonist antibody and Fas ligand mediate different sensitivity to death in the signaling pathways of Fas and cytoplasmic mutants , 1997, European journal of immunology.

[29]  S. Døskeland,et al.  Fas/APO-1(CD95)-induced apoptosis of primary hepatocytes is inhibited by cAMP. , 1997, Biochemical and biophysical research communications.

[30]  B. Fadeel,et al.  Anti-Fas IgG1 antibodies recognizing the same epitope of Fas/APO-1 mediate different biological effects in vitro. , 1997, International immunology.

[31]  G. Feldmann.  Liver apoptosis. , 1997, Journal of hepatology.

[32]  M. Leal,et al.  Human immunodeficiency virus infection modifies the natural history of chronic parenterally-acquired hepatitis C with an unusually rapid progression to cirrhosis. , 1997, Journal of hepatology.

[33]  S. Nagata,et al.  Lethal effect of the anti-Fas antibody in mice , 1993, Nature.