Thermobrachytherapy: Requirements for the Future

Brachytherapy provides an obvious and sometimes ideal setting for combining hyperthermia with radiation therapy. Such combination therapy has been done in the past primarily using microwave technology where multiple antennae are placed intra- tumorally into plastic catheters previously inserted for this purpose (e.g., Perez and Emami 1985; Couglin and Strohbehn 1989). There are a number of situations, particularly in the head and neck region, where this methodology is useful but does not lend itself easily to automation and does not adapt well to the simultaneous application of afterloaders. Another situation where hyperthermia can and has been applied (e.g., Aristizabal and Oleson 1984; Kong et al. 1986; Vora et al. 1987) is for implants that involve stainless steel needles to contain the radioactive materials which are usually done in conjunction with a cutaneously attached template guidance apparatus (e.g., Martinez et al. 1984). Other approaches include needles heated with electrical heating elements (Garcia et al. 1992)

[1]  S. Sapareto,et al.  A proposed standard data file format for hyperthermia treatments. , 1989, International journal of radiation oncology, biology, physics.

[2]  Z. Petrovich,et al.  Heating characteristics of a helical microwave applicator for transurethral hyperthermia of benign prostatic hyperplasia. , 1991, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[3]  J R Stewart,et al.  Phase I evaluation of hyperthermia equipment--University of Utah institutional report. , 1988, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[4]  M. Dewhirst,et al.  RTOG quality assurance guidelines for interstitial hyperthermia. , 1991, International journal of radiation oncology, biology, physics.

[5]  A. Martinez,et al.  A multiple-site perineal applicator (MUPIT) for treatment of prostatic, anorectal, and gynecologic malignancies. , 1984, International journal of radiation oncology, biology, physics.

[6]  J. Oleson,et al.  Clinical evaluation of hyperthermia equipment: the University of Arizona Institutional Report for the NCI Hyperthermia Equipment Evaluation Contract. , 1988, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[7]  J. Oleson,et al.  Combined interstitial irradiation and localized current field hyperthermia: results and conclusions from clinical studies. , 1984, Cancer research.

[8]  Alvaro Martinez,et al.  Elimination of dose-rate effects by mild hyperthermia. , 1992, International journal of radiation oncology, biology, physics.

[9]  R S Cox,et al.  Stanford University institutional report. Phase I evaluation of equipment for hyperthermia treatment of cancer. , 1988, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[10]  P. Stauffer,et al.  Thermal distribution studies of helical coil microwave antennas for interstitial hyperthermia. , 1988, International journal of radiation oncology, biology, physics.

[11]  Foi J. McCraw,et al.  Evaluation of equipment for hyperthermic treatment of cancer. , 1988, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[12]  P. Corry,et al.  Equivalence of continuous and pulse simulated low dose rate irradiation in 9L gliosarcoma cells at 37° and 41°C , 1992 .

[13]  C. Ling,et al.  Moderate hyperthermia and low dose rate irradiation. , 1988, Radiation research.

[14]  P. Corry,et al.  Sensitization of Rat 9L Gliosarcoma Cells to Low Dose Rate Irradiation by Long Duration 41°C Hyperthermia , 1991 .

[15]  J. Archambeau,et al.  Interstitial implant with interstitial hyperthermia , 1982, Cancer.