ANEMIA AND HYPOPROTEINEMIA COMPLICATING SEVERE PROTRACTED PNEUMONIA: TREATMENT WITH PENICILLIN— ROLE OF SPECIFIC SUPPORTIVE THERAPY IN RECOVERY

In writing of the symptomatic treatment of pneumonia inThe Journalin 1921, Means and Barach 1 stated that "the hope for a true curative treatment for... pneumonia undoubtedly lies in the field of specific therapy.... it is our object while waiting for the... specific cure to consider... symptomatic treatment... in terms of morbid physiology." The cases here reported are of significance not merely as cures of severe infections by the most recent and perhaps most powerful of specific antibacterial agents. 2 They are presented as instances wherein supportive therapy has appeared as important as the antibacterial in recovery from a clinical status which, although hitherto rarely seen in pneumonia, may occur with increasing frequency as specific agents permit prolonged survival in the face of infections otherwise rapidly fatal. Thus it remains relevant in the management of those pneumonias for which specific therapy is available

[1]  R. J. Floody,et al.  PLASMA VOLUME AND "EXTRAVASCULAR THIOCYANATE SPACE" IN PNEUMOCOCCUS PNEUMONIA. , 1945, The Journal of clinical investigation.

[2]  G. Scatchard,et al.  CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. VI. THE OSMOTIC PRESSURE OF PLASMA AND OF SERUM ALBUMIN. , 1944, The Journal of clinical investigation.

[3]  C. G. Harford,et al.  Use of a synthetic diet for food allergy and typhoid. , 1944 .

[4]  C. Keefer,et al.  A Clinical Evaluation of Sulfamerazine , 1944 .

[5]  W. Tillett,et al.  The Treatment of Lobar Pneumonia and Pneumococcal Empyema with Penicillin. , 1944, Bulletin of the New York Academy of Medicine.

[6]  G. W. Thorn,et al.  Some Medical Aspects of Protein Foods. , 1943, American journal of public health and the nation's health.

[7]  W. Spink,et al.  SULFAMERAZINE: CLINICAL EVALUATION IN 116 CASES , 1943 .

[8]  N. Boyer.  Acute Hemolytic Anemia Following Sulfadiazine , 1943 .

[9]  A. Barach.  PHYSIOLOGICALLY DIRECTED THERAPY IN PNEUMONIA , 1942 .

[10]  A. Barach,et al.  AN OXYGEN MASK METERED FOR POSITIVE PRESSURE , 1942 .

[11]  C. Rammelkamp,et al.  A Method for Determining the Concentration of Penicillin in Body Fluids and Exudates∗ , 1942 .

[12]  F. C. Lowell,et al.  OBSERVATIONS ON THE INHIBITION OF SULFONAMIDE ACTION BY PARA-AMINOBENZOIC ACID. , 1941, The Journal of clinical investigation.

[13]  R. Heffron.  Pneumonia, with special reference to pneumococcus lobar pneumonia , 1939 .

[14]  T. Francis.  THE VALUE OF THE SKIN TEST WITH TYPE-SPECIFIC CAPSULAR POLYSACCHARIDE IN THE SERUM TREATMENT OF TYPE I PNEUMOCOCCUS PNEUMONIA , 1933, The Journal of experimental medicine.

[15]  R. Christie,et al.  BLOOD CHLORIDES IN CONDITIONS ASSOCIATED WITH PNEUMONIA , 1929, The Journal of experimental medicine.

[16]  F. Sunderman,et al.  STUDIES IN SERUM ELECTROLYTES: I. Concentration of Electrolytes and Non-electrolytes in the Serum during Lobar Pneumonia. , 1929, The Journal of clinical investigation.

[17]  R. Haden.  THE CLINICAL SIGNIFICANCE OF THE CHLORID METABOLISM IN LOBAR PNEUMONIA , 1927, Transactions of the American Climatological and Clinical Association. American Climatological and Clinical Association.

[18]  J. P. Peters,et al.  TOTAL ACID-BASE EQUILIBRIUM OF PLASMA IN HEALTH AND DISEASE V. MISCELLANEOUS PATHOLOGIC CONDITIONS , 1926 .

[19]  F. Peabody.  STUDIES OF THE INORGANIC METABOLISM IN PNEUMONIA WITH ESPECIAL REFERENCE TO CALCIUM AND MAGNESIUM , 1913, The Journal of experimental medicine.