Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
暂无分享,去创建一个
Christoph Schmitz | Lieve Moons | Philip Van Damme | Diether Lambrechts | Wim Robberecht | Mieke Dewerchin | Peter Carmeliet | Bart Rutten | Nico Mertens | Ludo Van Den Bosch | P. Carmeliet | D. Lambrechts | C. Schmitz | W. Robberecht | M. Moreno-Murciano | L. Moons | D. Collen | B. Rutten | P. Damme | M. Dewerchin | E. Storkebaum | E. Conway | N. Mertens | M. Mol | L. Bosch | H. Oh | Désiré Collen | Hideyasu Oh | Erik Storkebaum | Edward M Conway | D. Manka | Sabine Wyns | S. Wyns | David Manka | Maria De Mol | Maria-Paz Moreno-Murciano | Saskia Appelmans | Wing Yan Man | Kristel Vermeulen | S. Appelmans | W. Y. Man | K. Vermeulen | M. Moreno‐Murciano | M. D. Mol
[1] W. Channing. Never Too Late to Mend , 1859 .
[2] W. H. Holden. It is never too late to mend , 1930 .
[3] P. Caroni,et al. Role of muscle insulin-like growth factors in nerve sprouting: suppression of terminal sprouting in paralyzed muscle by IGF-binding protein 4 , 1994, The Journal of cell biology.
[4] Rudolf Jaenisch,et al. Mice lacking brain-derived neurotrophic factor develop with sensory deficits , 1994, Nature.
[5] M. Gurney,et al. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. , 1994, Science.
[6] J. Belleroche,et al. Investigation of a null mutation of the CNTF gene in familial amyotrophic lateral sclerosis , 1995, Journal of the Neurological Sciences.
[7] A. Windebank. Use of growth factors in the treatment of motor neuron diseases. , 1995, Advances in neurology.
[8] F. L. Watson,et al. Rapid Nuclear Responses to Target-Derived Neurotrophins Require Retrograde Transport of Ligand–Receptor Complex , 1999, The Journal of Neuroscience.
[9] L. Powell-Braxton,et al. IGF-I deficient mice show reduced peripheral nerve conduction velocities and decreased axonal diameters and respond to exogenous IGF-I treatment. , 1999, Journal of neurobiology.
[10] D. Volles,et al. Pharmacokinetic considerations. , 1999, Critical care clinics.
[11] K. Koishi,et al. Anterograde axonal transport of glial cell line-derived neurotrophic factor and its receptors in rat hypoglossal nerve , 2000, Neuroscience.
[12] F. Condé,et al. Major strain differences in response to chronic systemic administration of the mitochondrial toxin 3-nitropropionic acid in rats: implications for neuroprotection studies , 2000, Neuroscience.
[13] W. Frey,et al. Delivery of Neurotrophic Factors to the Central Nervous System , 2001, Clinical pharmacokinetics.
[14] Till Acker,et al. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration , 2001, Nature Genetics.
[15] Robert H. Brown,et al. Rats Expressing Human Cytosolic Copper–Zinc Superoxide Dismutase Transgenes with Amyotrophic Lateral Sclerosis: Associated Mutations Develop Motor Neuron Disease , 2001, The Journal of Neuroscience.
[16] W. Robberecht,et al. Amyotrophic lateral sclerosis: pathogenesis. , 2000, Seminars in neurology.
[17] J. O’Kusky,et al. Mutant mouse models of insulin-like growth factor actions in the central nervous system , 2002, Neuropeptides.
[18] C. Geis,et al. Anterograde transport of tumor necrosis factor-alpha in the intact and injured rat sciatic nerve. , 2002, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[19] J. Rothstein,et al. Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS) , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[20] P. Caroni,et al. Accumulation of SOD1 Mutants in Postnatal Motoneurons Does Not Cause Motoneuron Pathology or Motoneuron Disease , 2002, The Journal of Neuroscience.
[21] Mart Saarma,et al. The GDNF family: Signalling, biological functions and therapeutic value , 2002, Nature Reviews Neuroscience.
[22] A. Luttun,et al. Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1 , 2002, Nature Medicine.
[23] Michael Sendtner,et al. Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches , 2002, Nature Neuroscience.
[24] C. Geis,et al. Anterograde Transport of Tumor Necrosis Factor-α in the Intact and Injured Rat Sciatic Nerve , 2002, The Journal of Neuroscience.
[25] B. Müller-Myhsok,et al. Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene. , 2002, American journal of human genetics.
[26] R. Segal,et al. Location, location, location: a spatial view of neurotrophin signal transduction , 2002, Trends in Neurosciences.
[27] M. Azari,et al. Behavioural and anatomical effects of systemically administered leukemia inhibitory factor in the SOD1G93A G1H mouse model of familial amyotrophic lateral sclerosis , 2003, Brain Research.
[28] L. Austin,et al. The effect of leukaemia inhibitory factor on SOD1 G93A murine amyotrophic lateral sclerosis. , 2003, Cytokine.
[29] F. Gage,et al. Retrograde Viral Delivery of IGF-1 Prolongs Survival in a Mouse ALS Model , 2003, Science.
[30] S. McMahon,et al. Glial cell line‐derived neurotrophic factor increases calcitonin gene‐related peptide immunoreactivity in sensory and motoneurons in vivo , 2003, The European journal of neuroscience.
[31] J. Rothstein. Of mice and men: Reconciling preclinical ALS mouse studies and human clinical trials , 2003, Annals of neurology.
[32] P. Carmeliet,et al. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death , 2003, Nature Genetics.
[33] N. Ferrara,et al. The biology of VEGF and its receptors , 2003, Nature Medicine.
[34] M. Strupp. Recent advances in amyotrophic lateral sclerosis research , 2004, Journal of Neurology.
[35] P. Aebischer,et al. ALS, IGF-1 and gene therapy: ‘it's never too late to mend’ , 2004, Gene Therapy.
[36] Peter Carmeliet,et al. VEGF: a critical player in neurodegeneration. , 2004, The Journal of clinical investigation.
[37] P. Carmeliet,et al. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model , 2004, Nature.