Heartbeat OCT: a new tool for interventional imaging (Conference Presentation)

We have developed a super fast intravascular optical coherence tomography (OCT) system called Heartbeat OCT. Heartbeat OCT relies on a Fourier Domain Mode Locked (FDML) laser and a micro-motor based catheter. The system enables acquisition of a uniformly sampled data set within one cardiac cycle, triggered by the ECG, to restore 3D OCT image fidelity. Here, we present a robust and easy to operate preclinical prototype system for interventional imaging which greatly facilitates data acquisition. The new system is using a fully automatic 1.6 MHz turnkey FDML laser with increased stability. The entire system was mounted into a 1.6 x 0.8 x 0.7 m cart. It is coupled to a guidewire compatible rapid-exchange catheter that can be used for routine imaging. The system is robust, compact, and moveable. We present the design, demonstrate ex-vivo imaging results and discuss in-vivo applications, as well as considerations for clinical translation of the technology. The ex-vivo imaging experiments were conducted with metal stents and bioresorbable vascular scaffold. The images provide clear and comprehensive visualization of the stents structure not only in cross-section but also in longitudinal rendering and 3D construction.