Elastoacoustic model with uncertain mechanical properties for ultrasonic wave velocity prediction: application to cortical bone evaluation.

The axial transmission technique can measure the longitudinal wave velocity of an immersed solid. An elementary model of the technique is developed with a set of source and receivers placed in a semi-infinite fluid coupled at a plane interface with a semi-infinite solid. The acoustic fluid is homogeneous. The solid is homogeneous, isotropic, and linearly elastic. The work is focused on the prediction of the measured velocity (apparent velocity) when the solid is considered to have random material properties. The probability density functions of the random variables modeling each mechanical parameter of the solid are derived following the maximum entropy principle. Specific attention is paid to the modeling of Poisson's ratio so that the second-order moments of the velocities remain finite. The stochastic solver is based on a Monte Carlo numerical simulation and uses an exact semianalytic expression of the acoustic response derived with the Cagniard-de Hoop method. Results are presented for a solid with the material properties of cortical bone. The estimated mean values and confidence regions of the apparent velocity are presented for various dispersion levels of the random parameters. A sensibility analysis with respect to the source and receivers locations is presented.

[1]  E. Bossy,et al.  Effect of bone cortical thickness on velocity measurements using ultrasonic axial transmission: a 2D simulation study. , 2002, The Journal of the Acoustical Society of America.

[2]  Salah Naili,et al.  A theoretical analysis in the time-domain of wave reflection on a bone plate , 2006 .

[3]  J. Roebuck,et al.  Waves in layered media , 1981 .

[4]  Ing Rj Ser Approximation Theorems of Mathematical Statistics , 1980 .

[5]  Louis Cagniard,et al.  Réflexion et réfraction des ondes séismiques progressives , 1939 .

[6]  William Thomlinson,et al.  Quantitative measurement of regional lung gas volume by synchrotron radiation computed tomography , 2005, Physics in medicine and biology.

[7]  A. T. Hoop,et al.  A modification of cagniard’s method for solving seismic pulse problems , 1960 .

[8]  J. N. Kapur,et al.  Entropy optimization principles with applications , 1992 .

[9]  M. Popovtzer,et al.  Quantitative ultrasound of the tibia: a novel approach for assessment of bone status. , 1995, Bone.

[10]  B. Kennett,et al.  Seismic Wave Propagation in Stratified Media , 1983 .

[11]  X Edward Guo,et al.  The dependence of transversely isotropic elasticity of human femoral cortical bone on porosity. , 2004, Journal of biomechanics.

[12]  Joseph Henricus Maria Titus Vanderhijden Propagation of transient elastic waves in stratified anisotropic media , 1987 .

[13]  C Soize,et al.  Maximum entropy approach for modeling random uncertainties in transient elastodynamics. , 2001, The Journal of the Acoustical Society of America.

[14]  Emmanuel Bossy Evaluation ultrasonore de l'os cortical par transmission axiale : modélisation et expérimentation in vitro et in vivo , 2003 .

[15]  G Van der Perre,et al.  Ultrasound velocity measurement in long bones: measurement method and simulation of ultrasound wave propagation. , 1996, Journal of biomechanics.

[16]  J. N. Kapur,et al.  Entropy Optimization Principles and Their Applications , 1992 .

[17]  Christian Soize Random-field model for the elasticity tensor of anisotropic random media , 2004, Comptes Rendus Mécanique.

[18]  F. Patat,et al.  Bidirectional axial transmission can improve accuracy and precision of ultrasonic velocity measurement in cortical bone: a validation on test materials , 2004, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[19]  P. G. Ciarlet,et al.  Introduction to Numerical Linear Algebra and Optimisation , 1989 .

[20]  E. Jaynes Information Theory and Statistical Mechanics , 1957 .

[21]  J. Virieux P-SV wave propagation in heterogeneous media: Velocity‐stress finite‐difference method , 1986 .

[22]  S. Goldstein,et al.  Elastic modulus and hardness of cortical and trabecular bone lamellae measured by nanoindentation in the human femur. , 1999, Journal of biomechanics.

[23]  Christian Soize Random matrix theory for modeling uncertainties in computational mechanics , 2005 .

[24]  Paul G. Richards,et al.  Quantitative Seismology: Theory and Methods , 1980 .

[25]  Sang Joon Kim,et al.  A Mathematical Theory of Communication , 2006 .

[26]  A. T. Hoop,et al.  Generation of acoustic waves by an impulsive point source in a fluid/porous‐medium configuration with a plane boundary , 1983 .

[27]  Robin O Cleveland,et al.  Derivation of elastic stiffness from site-matched mineral density and acoustic impedance maps , 2006, Physics in medicine and biology.

[28]  Yih-Hsing Pao,et al.  The Generalized Ray Theory and Transient Responses of Layered Elastic Solids , 1977 .