A MINLP approach for layout designs based on the domino hazard index

Abstract The Domino Hazard Index used in this work was previously introduced by Tugnoli et al., 2008a , Tugnoli et al., 2008b to assess domino effect hazards caused by a unit in a given layout. This index has been used to compare several layouts in order to select the one with lower risk. A set of piecewise differentiable equations have been developed to describe all graphical descriptions given in the original proposal. Then, this work introduces a complete formulation aimed to achieve optimal facility layouts taking into account the main variables affecting this index. The result of this formulation is a mixed-integer non-linear program (MINLP), which can be solved using a GAMS code. The result can provide substantial support for decision-makers during the design stage.

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