Protective effect of chlorpromazine against the lethality of interleukin 1 in adrenalectomized or actinomycin D-sensitized mice.

[1]  P. Ghezzi,et al.  Dexamethasone Modulation of In Vivo Effects of Endotoxin, Tumor Necrosis Factor, and Interleukin‐1 on Liver Cytochrome P‐450, Plasma Fibrinogen, and Serum Iron , 1989, Journal of leukocyte biology.

[2]  A. Bennett,et al.  Factors regulating the secretion of lysophosphatidylcholine by rat hepatocytes compared with the synthesis and secretion of phosphatidylcholine and triacylglycerol. Effects of albumin, cycloheximide, verapamil, EGTA and chlorpromazine. , 1988, The Biochemical journal.

[3]  C. Dinarello,et al.  Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism , 1988, Cell.

[4]  R. Ulevitch,et al.  Participation of tumor necrosis factor in the mediation of gram negative bacterial lipopolysaccharide-induced injury in rabbits. , 1988, The Journal of clinical investigation.

[5]  H. Holtmann,et al.  Sensitization and desensitization to lethal effects of tumor necrosis factor and IL-1. , 1988, Journal of immunology.

[6]  P. Ghezzi,et al.  Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor , 1988, The Journal of experimental medicine.

[7]  T. Ikejima,et al.  Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition. , 1988, The Journal of clinical investigation.

[8]  Kevin J. Tracey,et al.  Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia , 1987, Nature.

[9]  J. D. Albert,et al.  Shock and tissue injury induced by recombinant human cachectin. , 1986, Science.

[10]  B. Beutler,et al.  Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance. , 1986, Science.

[11]  P. Martín-Sanz,et al.  Relationship between the displacement of phosphatidate phosphohydrolase from the membrane-associated compartment by chlorpromazine and the inhibition of the synthesis of triacylglycerol and phosphatidylcholine in rat hepatocytes. , 1986, Biochimica et biophysica acta.

[12]  B. Beutler,et al.  Cachectin and tumour necrosis factor as two sides of the same biological coin , 1986, Nature.

[13]  B. Beutler,et al.  Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. , 1985, Science.

[14]  K. Shakir,et al.  Enhanced phospholipase A2 activity in rat plasma, liver, and intestinal mucosa following endotoxin treatment: a possible explanation for the protective effect of indomethacin in endotoxic shock. , 1985, Metabolism: clinical and experimental.

[15]  E. Unanue,et al.  Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production. , 1982, Journal of immunology.

[16]  P. Halushka,et al.  Ibuprofen improves survival from endotoxic shock in the rat. , 1980, Journal of Pharmacology and Experimental Therapeutics.

[17]  F. Halberg,et al.  Studies on the mechanism of chlorpromazine protection against Brucella endotoxin in mice. , 1957, The Journal of laboratory and clinical medicine.

[18]  P. Ghezzi,et al.  Dexamethasone modulation of LPS, IL-1, and TNF stimulated serum amyloid A synthesis in mice. , 1988, Lymphokine research.