A highly selective DNAzyme sensor for mercuric ions.

[1]  X. Qian,et al.  Two regioisomeric and exclusively selective Hg(II) sensor molecules composed of a naphthalimide fluorophore and an o-phenylenediamine derived triamide receptor. , 2006, Chemical communications.

[2]  R. Breaker,et al.  Deoxyribozymes: new activities and new applications , 2002, Cellular and Molecular Life Sciences CMLS.

[3]  Jing Li,et al.  A highly sensitive and selective catalytic DNA biosensor for lead ions [9] , 2000 .

[4]  Genhua Wu,et al.  A functionalized gold nanoparticles and Rhodamine 6G based fluorescent sensor for high sensitive and selective detection of mercury(II) in environmental water samples. , 2007, Analytica chimica acta.

[5]  X. Qian,et al.  A series of polyamide receptor based PET fluorescent sensor molecules: positively cooperative Hg2+ ion binding with high sensitivity. , 2006, Organic letters.

[6]  Injae Shin,et al.  In vivo monitoring of mercury ions using a rhodamine-based molecular probe. , 2006, Journal of the American Chemical Society.

[7]  A precipitator for the detection of thiophilic metals in aqua. , 2004, Journal of the American Chemical Society.

[8]  S. Silverman,et al.  Efficient one-step synthesis of biologically related lariat RNAs by a deoxyribozyme. , 2005, Angewandte Chemie.

[9]  Chuan He,et al.  Design of an emission ratiometric biosensor from MerR family proteins: a sensitive and selective sensor for Hg2+. , 2007, Journal of the American Chemical Society.

[10]  Hiroaki Ozaki,et al.  Modified DNA aptamer that binds the (R)-isomer of a thalidomide derivative with high enantioselectivity. , 2007, Journal of the American Chemical Society.

[11]  Directing the outcome of deoxyribozyme selections to favor native 3'-5' RNA ligation. , 2005, Biochemistry.

[12]  R. Humphry-Baker,et al.  Highly Selective and Reversible Optical, Colorimetric, and Electrochemical Detection of Mercury(II) by Amphiphilic Ruthenium Complexes Anchored onto Mesoporous Oxide Films , 2006 .

[13]  Yi Lu,et al.  A colorimetric lead biosensor using DNAzyme-directed assembly of gold nanoparticles. , 2003, Journal of the American Chemical Society.

[14]  Kevin W Plaxco,et al.  Electrochemical detection of parts-per-billion lead via an electrode-bound DNAzyme assembly. , 2007, Journal of the American Chemical Society.

[15]  J Li,et al.  In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme. , 2000, Nucleic acids research.

[16]  G. Joyce Vierzig Jahre Evolution im Reagenzglas , 2007 .

[17]  A. Peracchi DNA Catalysis: Potential, Limitations, Open Questions , 2005, Chembiochem : a European journal of chemical biology.

[18]  J. Szostak,et al.  A DNA metalloenzyme with DNA ligase activity , 1995, Nature.

[19]  Chuan He,et al.  A general strategy to convert the MerR family proteins into highly sensitive and selective fluorescent biosensors for metal ions. , 2004, Journal of the American Chemical Society.

[20]  R R Breaker,et al.  Capping DNA with DNA. , 2000, Biochemistry.

[21]  F. Morel,et al.  THE CHEMICAL CYCLE AND BIOACCUMULATION OF MERCURY , 1998 .

[22]  S. Silverman,et al.  DNA-catalyzed formation of nucleopeptide linkages. , 2008, Angewandte Chemie.

[23]  Yi Lu,et al.  A catalytic beacon sensor for uranium with parts-per-trillion sensitivity and millionfold selectivity , 2007, Proceedings of the National Academy of Sciences.

[24]  R. Breaker,et al.  Engineered allosteric ribozymes that respond to specific divalent metal ions , 2005, Nucleic acids research.

[25]  Chojiro Kojima,et al.  15N-15N J-coupling across Hg(II): direct observation of Hg(II)-mediated T-T base pairs in a DNA duplex. , 2007, Journal of the American Chemical Society.

[26]  V. Kuban,et al.  Mercury speciation by CE: A review , 2007, Electrophoresis.

[27]  Chad A Mirkin,et al.  Colorimetric detection of mercuric ion (Hg2+) in aqueous media using DNA-functionalized gold nanoparticles. , 2007, Angewandte Chemie.

[28]  G. F. Joyce,et al.  Forty years of in vitro evolution. , 2007, Angewandte Chemie.

[29]  Jiasheng Wu,et al.  Calix[4]arene-based, Hg2+ -induced intramolecular fluorescence resonance energy transfer chemosensor. , 2007, The Journal of organic chemistry.

[30]  Juewen Liu,et al.  Accelerated color change of gold nanoparticles assembled by DNAzymes for simple and fast colorimetric Pb2+ detection. , 2004, Journal of the American Chemical Society.

[31]  Chih-Ching Huang,et al.  Parameters for selective colorimetric sensing of mercury(II) in aqueous solutions using mercaptopropionic acid-modified gold nanoparticles. , 2007, Chemical communications.

[32]  Matthew M. Rex,et al.  Pushing the limits of mercury sensors with gold nanorods. , 2006, Analytical chemistry.

[33]  N. Davidson,et al.  Mercury(II) Complexes of Imidazole and Histidine , 1960 .

[34]  R R Breaker,et al.  Phosphorylating DNA with DNA. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[35]  Yi Lu New transition-metal-dependent DNAzymes as efficient endonucleases and as selective metal biosensors. , 2002, Chemistry.

[36]  P. Adriaens,et al.  In Vitro Selection of Hg (II) and As (V)-Dependent RNA-Cleaving DNAzymes , 2007 .

[37]  Juyoung Yoon,et al.  Selectively chemodosimetric detection of Hg(II) in aqueous media. , 2007, Organic letters.

[38]  Evan W. Miller,et al.  A bright and specific fluorescent sensor for mercury in water, cells, and tissue. , 2007, Angewandte Chemie.

[39]  Whitney E. Purtha,et al.  General deoxyribozyme-catalyzed synthesis of native 3'-5' RNA linkages. , 2005, Journal of the American Chemical Society.

[40]  D. Segal,et al.  Uranyl acetate as a direct inhibitor of DNA-binding proteins. , 2007, Chemical research in toxicology.

[41]  Stephen J Lippard,et al.  Turn-on and ratiometric mercury sensing in water with a red-emitting probe. , 2007, Journal of the American Chemical Society.

[42]  R R Breaker,et al.  A DNA enzyme that cleaves RNA. , 1994, Chemistry & biology.

[43]  Richard Ting,et al.  High affinity DNAzyme-based ligands for transition metal cations - a prototype sensor for Hg2+. , 2004, Organic & biomolecular chemistry.

[44]  T. Carell,et al.  DNA--metal base pairs. , 2007, Angewandte Chemie.

[45]  Samuel P. Kounaves,et al.  Microfabricated Array of Iridium Microdisks as a Substrate for Direct Determination of Cu2+ or Hg2+ Using Square-Wave Anodic Stripping Voltammetry , 1999 .

[46]  Takashi Fujimoto,et al.  MercuryII-mediated formation of thymine-HgII-thymine base pairs in DNA duplexes. , 2006, Journal of the American Chemical Society.

[47]  Yi Lu,et al.  A DNAzyme catalytic beacon sensor for paramagnetic Cu2+ ions in aqueous solution with high sensitivity and selectivity. , 2007, Journal of the American Chemical Society.

[48]  W. K. Ayensu,et al.  Review: Environmental exposure to mercury and its toxicopathologic implications for public health , 2003, Environmental toxicology.

[49]  R. Breaker Engineered allosteric ribozymes as biosensor components. , 2002, Current opinion in biotechnology.

[50]  W. Shotyk,et al.  Predominant anthropogenic sources and rates of atmospheric mercury accumulation in southern Ontario recorded by peat cores from three bogs: comparison with natural "background" values (past 8000 years). , 2003, Journal of environmental monitoring : JEM.

[51]  Pascal Salaün,et al.  Voltammetric detection of mercury and copper in seawater using a gold microwire electrode. , 2006, Analytical chemistry.

[52]  Y. Roupioz,et al.  Toward an RNaseA mimic: A DNAzyme with imidazoles and cationic amines. , 2002, Journal of the American Chemical Society.

[53]  Jin-Gou Xu,et al.  Switching the recognition preference of rhodamine B spirolactam by replacing one atom: design of rhodamine B thiohydrazide for recognition of Hg(II) in aqueous solution. , 2006, Organic letters.

[54]  G. F. Joyce,et al.  RNA cleavage by a DNA enzyme with extended chemical functionality. , 2000, Journal of the American Chemical Society.

[55]  R. Breaker,et al.  Immobilized RNA switches for the analysis of complex chemical and biological mixtures , 2001, Nature Biotechnology.

[56]  D. Ramaiah,et al.  Dual-mode semisquaraine-based sensor for selective detection of Hg2+ in a micellar medium. , 2007, Organic letters.

[57]  U. Bunz,et al.  Modulating the sensory response of a conjugated polymer by proteins: an agglutination assay for mercury ions in water. , 2006, Journal of the American Chemical Society.

[58]  J. Grasby,et al.  Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities. , 2004, Nucleic acids research.

[59]  A. Jäschke,et al.  Nucleic acid enzymes. , 2005, Current opinion in biotechnology.

[60]  H. Liljestrand,et al.  A 'turn-on' FRET peptide sensor based on the mercury binding protein MerP. , 2008, The Analyst.

[61]  R. Martínez‐Máñez,et al.  Highly selective chromogenic signaling of Hg2+ in aqueous media at nanomolar levels employing a squaraine-based reporter. , 2004, Inorganic chemistry.

[62]  G. F. Joyce,et al.  A general purpose RNA-cleaving DNA enzyme. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[63]  Yan Zhao,et al.  Tuning the sensitivity of a foldamer-based mercury sensor by its folding energy. , 2006, Journal of the American Chemical Society.

[64]  S. Silverman In vitro selection, characterization, and application of deoxyribozymes that cleave RNA , 2005, Nucleic acids research.

[65]  D. Perrin,et al.  Expanding the catalytic repertoire of nucleic acid catalysts: simultaneous incorporation of two modified deoxyribonucleoside triphosphates bearing ammonium and imidazolyl functionalities. , 1999, Nucleosides & nucleotides.

[66]  Marko Virta,et al.  Detection of bioavailable heavy metals in EILATox‐Oregon samples using whole‐cell luminescent bacterial sensors in suspension or immobilized onto fibre‐optic tips , 2004, Journal of applied toxicology : JAT.

[67]  Laszlo Magos,et al.  The toxicology of mercury--current exposures and clinical manifestations. , 2003, The New England journal of medicine.

[68]  Ronald R. Breaker,et al.  In vitro selection of self-cleaving DNAs. , 1996, Chemistry & biology.

[69]  Juewen Liu,et al.  Colorimetric Cu2+ detection with a ligation DNAzyme and nanoparticles. , 2007, Chemical communications.

[70]  Yi Lu,et al.  Rational design of "turn-on" allosteric DNAzyme catalytic beacons for aqueous mercury ions with ultrahigh sensitivity and selectivity. , 2007, Angewandte Chemie.

[71]  P. Zhou,et al.  Extraction of oxidized and reduced forms of uranium from contaminated soils: effects of carbonate concentration and pH. , 2005, Environmental science & technology.

[72]  S. Silverman,et al.  Deoxyribozymes: DNA catalysts for bioorganic chemistry. , 2004, Organic & biomolecular chemistry.

[73]  G. F. Joyce,et al.  Directed evolution of nucleic acid enzymes. , 2003, Annual review of biochemistry.

[74]  J. Bryson,et al.  Mercury-199 NMR of the metal receptor site in MerR and its protein-DNA complex. , 1995, Science.

[75]  A. Ono,et al.  Highly selective oligonucleotide-based sensor for mercury(II) in aqueous solutions. , 2004, Angewandte Chemie.

[76]  T. Carell,et al.  DNA‐Metall‐Basenpaare , 2007 .

[77]  Ramón Martínez-Máñez,et al.  Coupling selectivity with sensitivity in an integrated chemosensor framework: design of a Hg(2+)-responsive probe, operating above 500 nm. , 2003, Journal of the American Chemical Society.

[78]  A. Coskun,et al.  Signal ratio amplification via modulation of resonance energy transfer: proof of principle in an emission ratiometric Hg(II) sensor. , 2006, Journal of the American Chemical Society.

[79]  F. Carvalho,et al.  Mechanisms of cholinesterase inhibition by inorganic mercury , 2007, The FEBS journal.

[80]  Yi Lu,et al.  Stimuli-responsive disassembly of nanoparticle aggregates for light-up colorimetric sensing. , 2005, Journal of the American Chemical Society.

[81]  Richard Ting,et al.  Substrate specificity and kinetic framework of a DNAzyme with an expanded chemical repertoire: a putative RNaseA mimic that catalyzes RNA hydrolysis independent of a divalent metal cation. , 2004, Nucleic acids research.

[82]  Isabelle Leray,et al.  Highly selective and sensitive phosphane sulfide derivative for the detection of Hg2+ in an organoaqueous medium. , 2007, Organic letters.

[83]  Yingfu Li,et al.  Sequence diversity, metal specificity, and catalytic proficiency of metal-dependent phosphorylating DNA enzymes. , 2002, Chemistry & biology.

[84]  P. Haddad,et al.  Dithizone derivatives as sensitive water soluble chromogenic reagents for the ion chromatographic determination of inorganic and organo-mercury in aqueous matrices. , 2003, The Analyst.

[85]  Graham N George,et al.  The Chemical Form of Mercury in Fish , 2003, Science.

[86]  D. Perrin,et al.  Bridging the gap between proteins and nucleic acids: a metal-independent RNAseA mimic with two protein-like functionalities. , 2001, Journal of the American Chemical Society.

[87]  D. Chinnapen,et al.  A deoxyribozyme that harnesses light to repair thymine dimers in DNA , 2003, Proceedings of the National Academy of Sciences of the United States of America.