Chronic granulomatous disease presenting in a 69-year-old man.

CHRONIC granulomatous disease is a rare inherited disease characterized by severe recurrent bacterial and fungal infections beginning in childhood.1 Phagocytes from patients with chronic granulomat...

[1]  S. Orkin,et al.  CCAAT displacement protein as a repressor of the myelomonocytic-specific gp91-phox gene promoter. , 1991, The Journal of biological chemistry.

[2]  A. de Klein,et al.  Point mutations in the beta-subunit of cytochrome b558 leading to X-linked chronic granulomatous disease. , 1991, Blood.

[3]  J. Curnutte,et al.  Molecular basis of chronic granulomatous disease [see comments] , 1991 .

[4]  H. Rosen,et al.  Resonance Raman and electron paramagnetic resonance structural investigations of neutrophil cytochrome b558. , 1991, The Journal of biological chemistry.

[5]  W. Nauseef,et al.  Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558. , 1991, The Journal of clinical investigation.

[6]  J. Spitznagel,et al.  Antibiotic proteins of human neutrophils. , 1990, The Journal of clinical investigation.

[7]  S. Orkin,et al.  Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease. , 1990, The Journal of clinical investigation.

[8]  D. Rotrosen,et al.  Evidence for a functional cytoplasmic domain of phagocyte oxidase cytochrome b558. , 1990, The Journal of biological chemistry.

[9]  W. Nauseef,et al.  Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation. , 1990, The Journal of clinical investigation.

[10]  D. Roos,et al.  Assembly and activation of the NADPH:O2 oxidoreductase in human neutrophils after stimulation with phorbol myristate acetate. , 1990, The Journal of biological chemistry.

[11]  R. Baehner,et al.  Chronic granulomatous disease of childhood: clinical, pathological, biochemical, molecular, and genetic aspects of the disease. , 1990, Pediatric pathology.

[12]  S. Orkin,et al.  A missense mutation in the neutrophil cytochrome b heavy chain in cytochrome-positive X-linked chronic granulomatous disease. , 1989, The Journal of clinical investigation.

[13]  W. Nauseef,et al.  Genetic variants of chronic granulomatous disease: prevalence of deficiencies of two cytosolic components of the NADPH oxidase system. , 1989, The New England journal of medicine.

[14]  J. Gallin,et al.  The molecular biology of selected phagocyte defects. , 1989, Blood reviews.

[15]  A. Segal The electron transport chain of the microbicidal oxidase of phagocytic cells and its involvement in the molecular pathology of chronic granulomatous disease. , 1989, Biochemical Society transactions.

[16]  S. Orkin,et al.  Absence of both the 91kD and 22kD subunits of human neutrophil cytochrome b in two genetic forms of chronic granulomatous disease. , 1989, Blood.

[17]  C. Nathan Respiratory burst in adherent human neutrophils: triggering by colony- stimulating factors CSF-GM and CSF-G , 1989 .

[18]  D. Rotrosen,et al.  Two forms of autosomal chronic granulomatous disease lack distinct neutrophil cytosol factors. , 1988, Science.

[19]  W. Nauseef,et al.  Two cytosolic neutrophil oxidase components absent in autosomal chronic granulomatous disease. , 1988, Science.

[20]  C. Nathan,et al.  The measurement of cytochrome b559 in polymorphonuclear leukocytes and macrophages in the presence of hemoglobin or mitochondrial cytochromes. , 1988, Analytical biochemistry.

[21]  S. Orkin,et al.  Partial Correction of the Phagocyte Defect in Patients with X-Linked Chronic Granulomatous Disease by Subcutaneous Interferon Gamma , 1988 .

[22]  J. Curnutte Classification of chronic granulomatous disease. , 1988, Hematology/oncology clinics of North America.

[23]  H. Murray Interferon-gamma, the activated macrophage, and host defense against microbial challenge. , 1988, Annals of internal medicine.

[24]  K. Mullis,et al.  Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. , 1988, Science.

[25]  S. Orkin,et al.  Molecular genetics of chronic granulomatous disease. , 1988, Immunodeficiency reviews.

[26]  J. Bellanti,et al.  Chronic granulomatous disease in an adult. , 1987, Southern medical journal.

[27]  A. Jesaitis,et al.  Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000. , 1987, The Journal of clinical investigation.

[28]  B. Babior,et al.  Activation of the respiratory burst oxidase in a fully soluble system from human neutrophils. , 1987, The Journal of biological chemistry.

[29]  M. Klempner,et al.  Human recombinant interleukin 1 beta has no effect on intracellular calcium or on functional responses of human neutrophils. , 1987, Journal of immunology.

[30]  A. Segal Absence of both cytochrome b−245 subunits from neutrophils in X-linked chronic granulomatous disease , 1987, Nature.

[31]  P. Parker,et al.  The X-linked chronic granulomatous disease gene codes for the β-chain of cytochrome b −245 , 1987, Nature.

[32]  S. Orkin,et al.  The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex , 1987, Nature.

[33]  A. Monaco,et al.  Cloning the gene for an inherited human disorder—chronic granulomatous disease—on the basis of its chromosomal location , 1986, Nature.

[34]  A. Monaco,et al.  Cloning the gene for the inherited disorder chronic granulomatous disease on the basis of its chromosomal location. , 1986, Cold Spring Harbor symposia on quantitative biology.

[35]  A. Segal,et al.  Absence of cytochrome b-245 in chronic granulomatous disease. A multicenter European evaluation of its incidence and relevance. , 1983, The New England journal of medicine.

[36]  P. Newburger,et al.  Prenatal diagnosis of chronic granulomatous disease. , 1979, The New England journal of medicine.

[37]  F. Sanger,et al.  DNA sequencing with chain-terminating inhibitors. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[38]  A. Fauci,et al.  Chronic granulomatous disease. Diagnosis in a 27-year-old man with Mycobacterium fortuitum. , 1975, JAMA.

[39]  C. Mogensen The glomerular permeability determined by dextran clearance using Sephadex gel filtration. , 1968, Scandinavian journal of clinical and laboratory investigation.