Can Emblica officinalis and Tinospora cordifolia supplementation possess immunomodulatory and adaptogenic properties in murrah buffalo calves

The present investigation was conducted to evaluate the combined effect of Emblica officinalis and Tinospora cordifolia supplementation on growth performance, hormonal and immune status in murrah buffalo calves. 14 day age unsupplementated 6 calves were taken as control, whereas 6 calves of treatment group were supplemented with combination of Emblica officinalis and Tinospora cordifolia (2:1) @ 450 mg/ kg body weight once a day orally for 28 days. The results indicated that, significant (p<0.05) higher body weight in treatment group as compare to control group. Serum cortisol concentration was significantly (p<0.05) lower in treatment group. Higher level of T4 hormone, immunoglobulins and adaptability coefficient was observed in Emblica officinalis and Tinospora cordifolia treated group. It indicated that combination of Emblica officinalis and Tinospora cordifolia possess immunogenic effect and by inducing a state of non-specific increase in resistance to diverse climatic conditions they help to prevent calf mortality.

[1]  B. T. Deshmukh,et al.  Serum Profile of Thyroid Hormones from Birth to Puberty in Buffalo Calves and Heifers , 2012 .

[2]  P. Bhandari,et al.  Emblica officinalis (Amla): A review of potential therapeutic applications , 2012 .

[3]  Talha Jawaid,et al.  ADAPTOGENIC AGENTS: A REVIEW , 2011 .

[4]  B. T. Deshmukh,et al.  Endocrine profile from birth to puberty in buffalo calves and heifers , 2011 .

[5]  Kaushal Kumar,et al.  Tinospora cordifolia (Willd.) Hook. f. and Thoms. (Guduchi) – validation of the Ayurvedic pharmacology through experimental and clinical studies , 2010, International journal of Ayurveda research.

[6]  I. Marai,et al.  Buffalo's biological functions as affected by heat stress - A review , 2010 .

[7]  A. Jain,et al.  Immunomodulatory role of neem oil affecting haemogram and plasma proteins of neonatal buffalo calves and cow calves vis-a-vis their dams , 2007 .

[8]  A. Lone,et al.  Plasma Protein Profile of Neonatal Buffalo Calves in Relation to the Protein Profile of Colostrum/Milk during First Week Following Parturition , 2003 .

[9]  Abel Francisco Sf,et al.  Serum immunoglobulin concentrations after feeding maternal colostrum or maternal colostrum plus colostral supplement to dairy calves. , 1993 .

[10]  J. Quigley,et al.  Serum immunoglobulin concentrations after feeding maternal colostrum or maternal colostrum plus colostral supplement to dairy calves. , 1993, American journal of veterinary research.

[11]  C. Kannan The Adrenal Gland , 1988, Clinical Surveys in Endocrinology.

[12]  G. A. Hébert Ammonium sulfate fractionation of sera: mouse, hamster, guinea pig, monkey, chimpanzee, swine, chicken, and cattle. , 1974, Applied microbiology.

[13]  F. Hartman,et al.  The adrenal gland , 1949 .