Vitamin D deficiency and kidney hyperfiltration: a mechanism of kidney injury?

Chronic kidney disease (CKD) is a public health problem, given that approximately 13% of adult Americans currently living with CKD (1). CKD is associated with a high risk of hospitalization, cardiovascular events and mortality (2).

[1]  N. Potischman,et al.  Vitamin D status in the United States, 2011-2014. , 2019, The American journal of clinical nutrition.

[2]  R. Feinn,et al.  Role of Vitamin D and Its Analogues in Diabetic Nephropathy: A Meta‐analysis , 2019, The American journal of the medical sciences.

[3]  A. Köttgen,et al.  Negative effect of vitamin D on kidney function: a Mendelian randomization study , 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[4]  J. Manson,et al.  Vitamin D and omega-3 trial to prevent and treat diabetic kidney disease: Rationale, design, and baseline characteristics. , 2018, Contemporary clinical trials.

[5]  T. Yoo,et al.  Severe vitamin D deficiency is a risk factor for renal hyperfiltration. , 2018, The American journal of clinical nutrition.

[6]  L. Kingsley,et al.  Vitamin D Status and Kidney Function Decline in HIV-Infected Men: A Longitudinal Study in the Multicenter AIDS Cohort Study. , 2017, AIDS research and human retroviruses.

[7]  Mary B Leonard,et al.  Executive summary of the 2017 KDIGO Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) Guideline Update: what's changed and why it matters. , 2017, Kidney international.

[8]  Jin Deng,et al.  Calcitriol in the treatment of IgA nephropathy with non-nephrotic range proteinuria: a meta-analysis of randomized controlled trials
. , 2017, Clinical nephrology.

[9]  B. Kestenbaum,et al.  Serum 25-Hydroxyvitamin D Concentration and Risk for Major Clinical Disease Events in a Community-Based Population of Older Adults , 2012, Annals of Internal Medicine.

[10]  D. Gardner,et al.  Effect of combining an ACE inhibitor and a VDR activator on glomerulosclerosis, proteinuria, and renal oxidative stress in uremic rats. , 2012, American journal of physiology. Renal physiology.

[11]  R. Light,et al.  Short-term vitamin D receptor activation increases serum creatinine due to increased production with no effect on the glomerular filtration rate. , 2011, Kidney international.

[12]  C. Gordon,et al.  Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. , 2011, The Journal of clinical endocrinology and metabolism.

[13]  JoAnn E. Manson,et al.  The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to Know , 2010, The Journal of clinical endocrinology and metabolism.

[14]  H. Parving,et al.  Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trial , 2010, The Lancet.

[15]  N. Powe,et al.  25-hydroxyvitamin D levels, race, and the progression of kidney disease. , 2009, Journal of the American Society of Nephrology : JASN.

[16]  R. Bilous,et al.  Is hyperfiltration associated with the future risk of developing diabetic nephropathy? A meta-analysis , 2009, Diabetologia.

[17]  C. Zoccali,et al.  Vitamin D levels and patient outcome in chronic kidney disease. , 2009, Kidney international.

[18]  B. Astor,et al.  25-hydroxyvitamin D levels and the risk of mortality in the general population. , 2008, Archives of internal medicine.

[19]  Keith C. Norris,et al.  Hypovitaminosis D in chronic kidney disease. , 2008, Clinical journal of the American Society of Nephrology : CJASN.

[20]  J. Coresh,et al.  Prevalence of chronic kidney disease in the United States. , 2007, JAMA.

[21]  B. Kestenbaum,et al.  25-Hydroxyvitamin D levels and albuminuria in the Third National Health and Nutrition Examination Survey (NHANES III). , 2007, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[22]  A. Levin,et al.  Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease. , 2007, Kidney international.

[23]  J. Chandler,et al.  The prevalence of vitamin D inadequacy amongst women with osteoporosis: an international epidemiological investigation , 2006, Journal of internal medicine.

[24]  Charles E McCulloch,et al.  Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. , 2004, The New England journal of medicine.

[25]  Shu Q. Liu,et al.  1,25-Dihydroxyvitamin D3 is a negative endocrine regulator of the renin-angiotensin system , 2002 .

[26]  Shu Q. Liu,et al.  1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. , 2002, The Journal of clinical investigation.

[27]  Teven,et al.  EFFECTS OF LOSARTAN ON RENAL AND CARDIOVASCULAR OUTCOMES IN TYPE 2 DIABETES AND NEPHROPATHY EFFECTS OF LOSARTAN ON RENAL AND CARDIOVASCULAR OUTCOMES IN PATIENTS WITH TYPE 2 DIABETES AND NEPHROPATHY , 2001 .

[28]  B. Brenner,et al.  The case for intrarenal hypertension in the initiation and progression of diabetic and other glomerulopathies. , 1982, The American journal of medicine.