Algorithm of chest wall keloid treatment

AbstractKeloids are common in the Asian population. Multiple or huge keloids can appear on the chest wall because of its tendency to develop acne, sebaceous cyst, etc. It is difficult to find an ideal treatment for keloids in this area due to the limit of local soft tissues and higher recurrence rate. This study aims at establishing an individualized protocol that could be easily applied according to the size and number of chest wall keloids.A total of 445 patients received various methods (4 protocols) of treatment in our department from September 2006 to September 2012 according to the size and number of their chest wall keloids. All of the patients received adjuvant radiotherapy in our hospital. Patient and Observer Scar Assessment Scale (POSAS) was used to assess the treatment effect by both doctors and patients. With mean follow-up time of 13 months (range: 6–18 months), 362 patients participated in the assessment of POSAS with doctors.Both the doctors and the patients themselves used POSAS to evaluate the treatment effect. The recurrence rate was 0.83%. There was an obvious significant difference (P < 0.001) between the before-surgery score and the after-surgery score from both doctors and patients, indicating that both doctors and patients were satisfied with the treatment effect.Our preliminary clinical result indicates that good clinical results could be achieved by choosing the proper method in this algorithm for Chinese patients with chest wall keloids. This algorithm could play a guiding role for surgeons when dealing with chest wall keloid treatment.

[1]  M. Accardo,et al.  Clinical and histologic effects from CO2 laser treatment of keloids , 2013, Lasers in Medical Science.

[2]  G. Damodaran,et al.  Patient-Related Keloid Scar Assessment and Outcome Measures , 2012, Plastic and reconstructive surgery.

[3]  P. V. van Zuijlen,et al.  Perforator-Based Interposition Flaps for Sustainable Scar Contracture Release: A Versatile, Practical, and Safe Technique , 2011, Plastic and reconstructive surgery.

[4]  R. Ogawa,et al.  Clinical applications of basic research that shows reducing skin tension could prevent and treat abnormal scarring: the importance of fascial/subcutaneous tensile reduction sutures and flap surgery for keloid and hypertrophic scar reconstruction. , 2011, Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.

[5]  M. Saint-Cyr,et al.  Freestyle Pedicle Perforator Flaps: Clinical Results and Vascular Anatomy , 2010, Plastic and reconstructive surgery.

[6]  S. Gupta,et al.  Dermatitis artefacta: keloids and foreign body granuloma due to overvalued ideation of acupuncture. , 2009, Indian journal of dermatology, venereology and leprology.

[7]  N. Roche,et al.  Clinical applications of the superior epigastric artery perforator (SEAP) flap: anatomical studies and preoperative perforator mapping with multidetector CT. , 2009, Journal of plastic, reconstructive & aesthetic surgery : JPRAS.

[8]  R. Ogawa,et al.  Postoperative Radiation Protocol for Keloids and Hypertrophic Scars: Statistical Analysis of 370 Sites Followed for Over 18 Months , 2007, Annals of plastic surgery.

[9]  P. Hedén Nonsurgical Management of Hypertrophic Scars: Evidence-Based Therapies, Standard Practices, and Emerging Methods , 2007, Aesthetic Plastic Surgery.

[10]  A. Chuangsuwanich,et al.  The efficacy of 5% imiquimod cream in the prevention of recurrence of excised keloids. , 2007, Journal of the Medical Association of Thailand = Chotmaihet thangphaet.

[11]  S. Weitzul,et al.  Running Combined Simple and Vertical Mattress Suture: A Rapid Skin‐Everting Stitch , 2005, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[12]  S. Mutalik Treatment of keloids and hypertrophic scars. , 2005, Indian journal of dermatology, venereology and leprology.

[13]  R. Ogawa,et al.  A new skin closure technique with running sutures and tissue adhesive. , 2004, Plastic and reconstructive surgery.

[14]  F. Wood,et al.  [International clinical recommendations on scar management]. , 2002, Zentralblatt fur Chirurgie.

[15]  Hiko Hyakusoku,et al.  Postoperative Electron‐Beam Irradiation Therapy for Keloids and Hypertrophic Scars: Retrospective Study of 147 Cases Followed for More Than 18 Months , 2003, Plastic and reconstructive surgery.

[16]  M. Santiago,et al.  Keloidal scleroderma , 2003, Clinical Rheumatology.

[17]  D. Sherris,et al.  Scar Contractures, Hypertrophic Scars, and Keloids , 2001, Facial plastic surgery : FPS.

[18]  M. Bestué,et al.  Acne Keloidalis Nuchae: Tissue Expansion Treatment , 1995, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[19]  R. Nordström,et al.  Absorbable versus nonabsorbable sutures to prevent postoperative stretching of wound area. , 1986, Plastic and reconstructive surgery.

[20]  J. Clarke,et al.  Medicine , 1907, Bristol medico-chirurgical journal.