Identification of the genes encoding cancer antigens: implications for cancer immunotherapy.

[1]  B. Moss,et al.  Costimulation enhances the active immunotherapy effect of recombinant anticancer vaccines. , 1996, Cancer research.

[2]  A Sette,et al.  Melanoma-specific CD4+ T cells recognize nonmutated HLA-DR-restricted tyrosinase epitopes , 1996, The Journal of experimental medicine.

[3]  E. Appella,et al.  A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes , 1996, The Journal of experimental medicine.

[4]  S. Rosenberg,et al.  Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen , 1996, The Journal of experimental medicine.

[5]  S. Rosenberg,et al.  Cytokine enhancement of DNA immunization leads to effective treatment of established pulmonary metastases. , 1996, Journal of immunology.

[6]  S. Rosenberg,et al.  Vitiligo in patients with melanoma: normal tissue antigens can be targets for cancer immunotherapy. , 1996, Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.

[7]  S. Rosenberg,et al.  T-cell recognition of self peptides as tumor rejection antigens , 1996, Immunologic research.

[8]  N. Cascinelli,et al.  Tumor regression responses in melanoma patients treated with a peptide encoded by gene MAGES‐3 , 1995, International journal of cancer.

[9]  M F del Guercio,et al.  Prominent roles of secondary anchor residues in peptide binding to HLA-A24 human class I molecules. , 1995, Journal of immunology.

[10]  M. Salgaller,et al.  Recognition of multiple epitopes in the human melanoma antigen gp100 by peripheral blood lymphocytes stimulated in vitro with synthetic peptides. , 1995, Cancer research.

[11]  A. Houghton,et al.  Implicating a role for immune recognition of self in tumor rejection: passive immunization against the brown locus protein , 1995, The Journal of experimental medicine.

[12]  P. Romero,et al.  Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1 , 1995, The Journal of experimental medicine.

[13]  M. Serrano,et al.  A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma , 1995, Science.

[14]  O. de Backer,et al.  A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma , 1995, The Journal of experimental medicine.

[15]  P. Coulie,et al.  A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[16]  K. Sakaguchi,et al.  Identification of a tyrosinase epitope recognized by HLA-A24-restricted, tumor-infiltrating lymphocytes. , 1995, Journal of immunology.

[17]  E. Sercarz,et al.  Induction of anti-self-immunity to cure cancer , 1995, Cell.

[18]  C. Farina,et al.  Cytotoxic T-lymphocyte clones from different patients display limited T-cell-receptor variable-region gene usage in HLA-A2-restricted recognition of the melanoma antigen Melan-A/MART-1. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[19]  K. Sakaguchi,et al.  Cloning of a new gene encoding an antigen recognized by melanoma-specific HLA-A24-restricted tumor-infiltrating lymphocytes. , 1995, Journal of immunology.

[20]  Wei Chen,et al.  Immunity to Oncogenic Proteins , 1995, Immunological reviews.

[21]  J. Wharton,et al.  Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines , 1995, The Journal of experimental medicine.

[22]  S. Rosenberg,et al.  IL-2 enhances the function of recombinant poxvirus-based vaccines in the treatment of established pulmonary metastases. , 1995, Journal of immunology.

[23]  W. Kast,et al.  Induction and characterization of cytotoxic T‐lymphocytes recognizing a mutated p21ras peptide presented by HLA‐A*0201 , 1995, International journal of cancer.

[24]  M. Ressing,et al.  CTL specific for the tyrosinase autoantigen can be induced from healthy donor blood to lyse melanoma cells. , 1995, Journal of immunology.

[25]  A. Sette,et al.  Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression. , 1995, Journal of immunology.

[26]  J. Strominger,et al.  Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein , 1995, Cell.

[27]  Y. Niitsu,et al.  Loss of E-cadherin-dependent cell-cell adhesion due to mutation of the beta-catenin gene in a human cancer cell line, HSC-39 , 1995, Molecular and cellular biology.

[28]  A Sette,et al.  Induction of tumor-reactive CTL from peripheral blood and tumor-infiltrating lymphocytes of melanoma patients by in vitro stimulation with an immunodominant peptide of the human melanoma antigen MART-1. , 1995, Journal of immunology.

[29]  S. Rosenberg,et al.  Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen. , 1995, Cancer research.

[30]  R. Brasseur,et al.  BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes. , 1995, Immunity.

[31]  S. Rosenberg,et al.  Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes [published erratum appears in J Exp Med 1995 Mar 1;181(3):1261] , 1995, The Journal of experimental medicine.

[32]  T. Eberlein,et al.  Breast and ovarian cancer-specific cytotoxic T lymphocytes recognize the same HER2/neu-derived peptide. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[33]  M. Lotze,et al.  Mass spectrometric identification of a naturally processed melanoma peptide recognized by CD8+ cytotoxic T lymphocytes , 1995, The Journal of experimental medicine.

[34]  Andrew Brooks,et al.  Peptide binding to MHC class I molecules: Implications for antigenic peptide prediction , 1995, Immunologic research.

[35]  A. Vitiello,et al.  The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes. , 1994, Journal of immunology.

[36]  P. Coulie,et al.  A peptide encoded by human gene MAGE‐3 and presented by HLA‐A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE‐3 , 1994, European journal of immunology.

[37]  B. Kwon,et al.  The Pmel 17/silver locus protein. Characterization and investigation of its melanogenic function. , 1994, The Journal of biological chemistry.

[38]  C. Bordignon,et al.  Characterization of natural peptide ligands for HLA-B*4402 and -B*4403: implications for peptide involvement in allorecognition of a single amino acid change in the HLA-B44 heavy chain. , 1994, Tissue antigens.

[39]  T. Yasuda,et al.  Identification of a unique antigen peptide pRL1 on BALB/c RL male 1 leukemia recognized by cytotoxic T lymphocytes and its relation to the Akt oncogene , 1994, The Journal of experimental medicine.

[40]  S. Rosenberg,et al.  Identification of MART-1-specific T-cell receptors: T cells utilizing distinct T-cell receptor variable and joining regions recognize the same tumor epitope. , 1994, Cancer research.

[41]  D. Margulies,et al.  Determinant selection of major histocompatibility complex class I- restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues , 1994, The Journal of experimental medicine.

[42]  S. Rosenberg,et al.  Human CD4+ T cells specifically recognize a shared melanoma-associated antigen encoded by the tyrosinase gene. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[43]  C. Figdor,et al.  Molecular characterization of the melanocyte lineage-specific antigen gp100. , 1994, The Journal of biological chemistry.

[44]  S. Rosenberg,et al.  Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2. , 1994, Journal of the National Cancer Institute.

[45]  E. Sercarz,et al.  Can antitumor immune responses discriminate between self and nonself? , 1994, Immunology today.

[46]  K. Urabe,et al.  A new enzymatic function in the melanogenic pathway. The 5,6-dihydroxyindole-2-carboxylic acid oxidase activity of tyrosinase-related protein-1 (TRP1). , 1994, The Journal of biological chemistry.

[47]  K. Sakaguchi,et al.  Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[48]  S. Rosenberg,et al.  Melanoma‐specific CD4+ T lymphocytes recognize human melanoma antigens processed and presented by epstein‐barr virus‐transformed B cells , 1994, International journal of cancer.

[49]  K. Sakaguchi,et al.  Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes , 1994, The Journal of experimental medicine.

[50]  J. Renauld,et al.  A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas , 1994, The Journal of experimental medicine.

[51]  S. Rosenberg,et al.  Recognition of tyrosinase by tumor-infiltrating lymphocytes from a patient responding to immunotherapy. , 1994, Cancer research.

[52]  M. Eisenstein,et al.  CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma , 1994, Nature.

[53]  H. Rammensee,et al.  Isolation of naturally processed peptides recognized by cytolytic T lymphocytes (CTL) on human melanoma cells in association with HLA‐A2.1 , 1994, International journal of cancer.

[54]  R. Henderson,et al.  Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines. , 1994, Science.

[55]  S. Rosenberg,et al.  Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[56]  S. Rosenberg,et al.  Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2. , 1994, JAMA.

[57]  H. Grey,et al.  Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopes. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[58]  P. Romero,et al.  Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes , 1994, The Journal of experimental medicine.

[59]  C. Figdor,et al.  Melanocyte lineage-specific antigen gp100 is recognized by melanoma- derived tumor-infiltrating lymphocytes , 1994, The Journal of experimental medicine.

[60]  S. Becerra,et al.  Site-directed mutagenesis of adeno-associated virus type 2 structural protein initiation codons: effects on regulation of synthesis and biological activity , 1994, Journal of virology.

[61]  S. R. Hann,et al.  Regulation and function of non-AUG-initiated proto-oncogenes. , 1994, Biochimie.

[62]  H L Robinson,et al.  DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[63]  M. Lotze,et al.  Identification of human melanoma peptides recognized by class I restricted tumor infiltrating T lymphocytes. , 1993, Journal of immunology.

[64]  U. Schibler,et al.  CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[65]  S. H. van der Burg,et al.  In vitro induction of human cytotoxic T lymphocyte responses against peptides of mutant and wild‐type p53 , 1993, European journal of immunology.

[66]  S. Rosenberg,et al.  T-cell recognition of human melanoma antigens. , 1993, Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.

[67]  J. Yewdell,et al.  Detection of shared MHC-restricted human melanoma antigens after vaccinia virus-mediated transduction of genes coding for HLA. , 1993, Journal of immunology.

[68]  P. Coulie,et al.  Genes coding for tumor antigens recognized by human cytolytic T lymphocytes. , 1993, Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.

[69]  P. Coulie,et al.  The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas , 1993, The Journal of experimental medicine.

[70]  W. Isaacs,et al.  Reduction of E-Cadherin Levels and Deletion of the α-Catenin Gene in Human Prostate Cancer Cells , 1993 .

[71]  Y. Doki,et al.  Correlation between E-cadherin expression and invasiveness in vitro in a human esophageal cancer cell line. , 1993, Cancer research.

[72]  S. Nichol,et al.  A small highly basic protein is encoded in overlapping frame within the P gene of vesicular stomatitis virus , 1993, Journal of virology.

[73]  R. Henderson,et al.  Recognition of human melanoma cells by HLA-A2.1-restricted cytotoxic T lymphocytes is mediated by at least six shared peptide epitopes. , 1993, Journal of immunology.

[74]  M. Herlyn,et al.  Melanoma cells and normal melanocytes share antigens recognized by HLA- A2-restricted cytotoxic T cell clones from melanoma patients , 1993, The Journal of experimental medicine.

[75]  S. Rosenberg,et al.  Specific release of cytokines by lymphocytes infiltrating human melanomas in response to shared melanoma antigens. , 1993, Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.

[76]  E. Sercarz,et al.  Processing of self-proteins and its impact on shaping the T cell repertoire, autoimmunity and immune regulation. , 1993, International reviews of immunology.

[77]  A. Miller,et al.  Dominance and crypticity of T cell antigenic determinants. , 1993, Annual review of immunology.

[78]  G. Wistow,et al.  The cDNA RPE1 and monoclonal antibody HMB-50 define gene products preferentially expressed in retinal pigment epithelium. , 1992, Experimental eye research.

[79]  Catia,et al.  A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E , 1992, The Journal of experimental medicine.

[80]  J. Richards,et al.  Sequential chemoimmunotherapy in the treatment of metastatic melanoma. , 1992, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[81]  R. Henderson,et al.  Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. , 1992, Science.

[82]  S. Rosenberg,et al.  Shared human melanoma antigens. Recognition by tumor-infiltrating lymphocytes in HLA-A2.1-transfected melanomas. , 1992, Journal of immunology.

[83]  G. Pavlakis,et al.  Mechanism of translation of monocistronic and multicistronic human immunodeficiency virus type 1 mRNAs , 1992, Molecular and cellular biology.

[84]  T. Boon.  Toward a genetic analysis of tumor rejection antigens. , 1992, Advances in cancer research.

[85]  P. Chomez,et al.  A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. , 1991, Science.

[86]  E. Kaiserling,et al.  Ultrastructural localization of HMB‐45 binding sites , 1991, Journal of cutaneous pathology.

[87]  J. Simon,et al.  A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[88]  U. Schibler,et al.  A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the sam mRNA , 1991, Cell.

[89]  D. Barton,et al.  A melanocyte-specific gene, Pmel 17, maps near the silver coat color locus on mouse chromosome 10 and is in a syntenic region on human chromosome 12. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[90]  W. Fiers,et al.  Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role , 1991, Cell.

[91]  S. Rosenberg,et al.  Common Expression of Melanoma Tumor-Associated Antigens Recognized by Human Tumor Infiltrating Lymphocytes: Analysis by Human Lymphocyte Antigen Restriction , 1991, Journal of immunotherapy : official journal of the Society for Biological Therapy.

[92]  H. Rammensee,et al.  Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules , 1991, Nature.

[93]  S. Rosenberg,et al.  Specific release of granulocyte-macrophage colony-stimulating factor, tumor necrosis factor-alpha, and IFN-gamma by human tumor-infiltrating lymphocytes after autologous tumor stimulation. , 1991, Journal of immunology.

[94]  H. Seigler,et al.  MHC-restricted recognition of autologous melanoma by tumor-specific cytotoxic T cells. Evidence for restriction by a dominant HLA-A allele. , 1991, Journal of immunology.

[95]  K. Agata,et al.  Complete sequence and expression of a cDNA encoding a chicken 115-kDa melanosomal matrix protein. , 1991, Pigment cell research.

[96]  S. Shibahara,et al.  Nucleotide sequence of the cDNA encoding human tyrosinase-related protein. , 1990, Nucleic acids research.

[97]  A. Houghton,et al.  The melanoma antigen gp75 is the human homologue of the mouse b (brown) locus gene product , 1990, The Journal of experimental medicine.

[98]  A. Shatkin,et al.  Translation of bicistronic viral mRNA in transfected cells: regulation at the level of elongation. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[99]  R. Fauchet,et al.  Presence on a human melanoma of multiple antigens recognized by autologous CTL , 1989, International journal of cancer.

[100]  A. Houghton,et al.  Induction of pigmentation in mouse fibroblasts by expression of human tyrosinase cDNA , 1989, The Journal of experimental medicine.

[101]  C. Slingluff,et al.  The role of HLA class I antigens in recognition of melanoma cells by tumor-specific cytotoxic T lymphocytes. Evidence for shared tumor antigens. , 1989, Journal of immunology.

[102]  S. Rosenberg,et al.  Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report. , 1988, The New England journal of medicine.

[103]  W. Linehan,et al.  Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: a pilot study. , 1988, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[104]  F. Real,et al.  Differentiation antigens of melanocytes and melanoma: analysis of melanosome and cell surface markers of human pigmented cells with monoclonal antibodies. , 1988, The Journal of investigative dermatology.

[105]  R. Esclamado,et al.  Identification of a secreted Mr 95,000 glycoprotein in human melanocytes and melanomas by a melanocyte specific monoclonal antibody. , 1988, Cancer research.

[106]  D. Ruiter,et al.  A monoclonal antibody specific for cells of the melanocyte lineage. , 1988, The American journal of pathology.

[107]  S. Rosenberg,et al.  Expansion of human tumor infiltrating lymphocytes for use in immunotherapy trials. , 1987, Journal of immunological methods.

[108]  A. Kopf,et al.  Prognostic significance of hypopigmentation in malignant melanoma. , 1987, Archives of dermatology.

[109]  S. Rosenberg,et al.  Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma. , 1987, Journal of immunology.

[110]  C. Balch,et al.  Interleukin 2 activation of cytotoxic T-lymphocytes infiltrating into human metastatic melanomas. , 1986, Cancer research.

[111]  A. Gown,et al.  Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes. , 1986, The American journal of pathology.

[112]  L. Old,et al.  Pigmentation-associated glycoprotein of human melanomas and melanocytes: definition with a mouse monoclonal antibody. , 1985, The Journal of investigative dermatology.

[113]  L. Old,et al.  A pigmentation‐associated, differentiation antigen of human melanoma defined by a precipitating antibody in human serum , 1983, International journal of cancer.

[114]  J. Kirkwood,et al.  Vitiligo in patients with metastatic melanoma: a good prognostic sign. , 1983, Journal of the American Academy of Dermatology.

[115]  R. Lamb,et al.  A previously unrecognized influenza B virus glycoprotein from a bicistronic mRNA that also encodes the viral neuraminidase. , 1983, Proceedings of the National Academy of Sciences of the United States of America.