Isolation of a distinct serotype of porcine reproductive and respiratory syndrome (PRRS) virus in Ontario.

were confirmed positive in an indirect immunofluorescence test to determine IgG specific for a Canadian isolate of PRRS virus (Institut Armand Frappier). This is the earliest reported detection of antibody to PRRS virus worldwide. The long time between the presence of antibody and the recognition of disease in Ontario suggests that less virulent PRRS virus strains may have been circulating in Ontario prior to the severe disease outbreaks recognized in 1987.

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