Comparison of Form and Motion Coherence Processing in Autistic Spectrum Disorders and Dyslexia

A large body of research has reported visual perception deficits in both people with dyslexia and autistic spectrum disorders. In this study, we compared form and motion coherence detection between a group of adults with high-functioning autism, a group with Asperger’s disorder, a group with dyslexia, and a matched control group. It was found that motion detection was intact in dyslexia and Asperger. Individuals with high-functioning autism showed a general impaired ability to detect coherent form and motion. Participants with Asperger’s syndrome showed lower form coherence thresholds than the dyslexic and normally developing adults. The results are discussed with respect to the involvement of the dorsal and ventral pathways in developmental disorders.

[1]  L. Glass Moiré Effect from Random Dots , 1969, Nature.

[2]  H. Deubel,et al.  Current oculomotor research : physiological and psychological aspects , 1999 .

[3]  R. Turner,et al.  Form and motion coherence activate independent, but not dorsal/ventral segregated, networks in the human brain , 2000, Current Biology.

[4]  J. Faubert,et al.  Enhanced and diminished visuo-spatial information processing in autism depends on stimulus complexity. , 2005, Brain : a journal of neurology.

[5]  Karl J. Friston,et al.  A direct quantitative relationship between the functional properties of human and macaque V5 , 2000, Nature Neuroscience.

[6]  C. Dissanayake,et al.  Annotation: The similarities and differences between autistic disorder and Asperger's disorder: a review of the empirical evidence. , 2004, Journal of child psychology and psychiatry, and allied disciplines.

[7]  WH Merigan,et al.  Chromatic and achromatic vision of macaques: role of the P pathway , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[8]  William T. Newsome,et al.  Cortical microstimulation influences perceptual judgements of motion direction , 1990, Nature.

[9]  J F Stein,et al.  Are dyslexics’ visual deficits limited to measures of dorsal stream function? , 2001, Neuroreport.

[10]  Kevin J. Riggs,et al.  Motion processing in autism: evidence for a dorsal stream deficiency , 2000, Neuroreport.

[11]  Janine V. Spencer,et al.  Visual Form-Processing Deficits in Autism , 2006, Perception.

[12]  J. Atkinson,et al.  Normal and anomalous development of visual motion processing: motion coherence and ‘dorsal-stream vulnerability’ , 2003, Neuropsychologia.

[13]  J. Rumsey,et al.  Neuropsychological divergence of high-level autism and severe dyslexia , 1990, Journal of autism and developmental disorders.

[14]  J. Stein,et al.  Visual motion sensitivity in dyslexia: evidence for temporal and energy integration deficits , 2000, Neuropsychologia.

[15]  Ken Nakayama,et al.  Smooth Pursuit to a Movement Flow and Associated Perceptual Judgments , 1999 .

[16]  C. Gillberg,et al.  Asperger syndrome--some epidemiological considerations: a research note. , 1989, Journal of child psychology and psychiatry, and allied disciplines.

[17]  F. Volkmar,et al.  Validity and neuropsychological characterization of Asperger syndrome: convergence with nonverbal learning disabilities syndrome. , 1995, Journal of child psychology and psychiatry, and allied disciplines.

[18]  Leslie G. Ungerleider Two cortical visual systems , 1982 .

[19]  Chantal Kemner,et al.  Eye movements, visual attention, and autism: a saccadic reaction time study using the gap and overlap paradigm , 2001, Biological Psychiatry.

[20]  D. Badcock,et al.  Vernier acuity is normal in migraine, whereas global form and global motion perception are not. , 2006, Investigative ophthalmology & visual science.

[21]  W. Slaghuis,et al.  Spatio-temporal contrast sensitivity, coherent motion, and visible persistence in developmental dyslexia , 1999, Vision Research.

[22]  J. Stein,et al.  Differences in eye movements and reading problems in dyslexic and normal children , 1994, Vision Research.

[23]  J. Scharre,et al.  Assessment of Visual Function in Autistic Children , 1992, Optometry and vision science : official publication of the American Academy of Optometry.

[24]  J Swettenham,et al.  Children with autism show local precedence in a divided attention task and global precedence in a selective attention task. , 1999, Journal of child psychology and psychiatry, and allied disciplines.

[25]  N. Minshew,et al.  Pursuit eye movement deficits in autism. , 2004, Brain : a journal of neurology.

[26]  R. McCarley,et al.  Selective deficits in visual perception and recognition in schizophrenia , 1995, Biological Psychiatry.

[27]  K. H. Britten,et al.  Responses of neurons in macaque MT to stochastic motion signals , 1993, Visual Neuroscience.

[28]  P. Gelder,et al.  High thresholds for movement perception in schizophrenia may indicate abnormal extraneous noise levels of central vestibular activity , 1985, Biological Psychiatry.

[29]  Janette Atkinson,et al.  The Developing Visual Brain , 2000 .

[30]  Trichur Raman Vidyasagar Neural underpinnings of dyslexia as a disorder of visuo‐spatial attention , 2004, Clinical & experimental optometry.

[31]  U Rosenhall,et al.  Oculomotor findings in autistic children , 1988, The Journal of Laryngology & Otology.

[32]  C. Mazefsky,et al.  The discriminative ability and diagnostic utility of the ADOS-G, ADI-R, and GARS for children in a clinical setting , 2006, Autism : the international journal of research and practice.

[33]  R. Andersen,et al.  Functional analysis of human MT and related visual cortical areas using magnetic resonance imaging , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[34]  P. Szatmari,et al.  Asperger's syndrome and autism: differences in behavior, cognition, and adaptive functioning. , 1995, Journal of the American Academy of Child and Adolescent Psychiatry.

[35]  J. Faubert,et al.  Integrative cortical dysfunction and pervasive motion perception deficit in fragile X syndrome , 2004, Neurology.

[36]  M. Rizzo,et al.  Perception of movement and shape in Alzheimer's disease. , 1998, Brain : a journal of neurology.

[37]  J. Movshon,et al.  The analysis of visual motion: a comparison of neuronal and psychophysical performance , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[38]  R. Campbell,et al.  High motion coherence thresholds in children with autism. , 2002, Journal of child psychology and psychiatry, and allied disciplines.

[39]  N. Rinehart,et al.  Movement Preparation in High-Functioning Autism and Asperger Disorder: A Serial Choice Reaction Time Task Involving Motor Reprogramming , 2001, Journal of autism and developmental disorders.

[40]  D. Hubel,et al.  Segregation of form, color, movement, and depth: anatomy, physiology, and perception. , 1988, Science.

[41]  John H. R. Maunsell,et al.  How parallel are the primate visual pathways? , 1993, Annual review of neuroscience.

[42]  F. Ramus,et al.  Developmental dyslexia : specific phonological deficit or general sensorimotor dysfunction ? , 2003 .

[43]  Janette Atkinson,et al.  Neurobiological Models of Visuospatial Cognition in Children With Williams Syndrome: Measures of Dorsal-Stream and Frontal Function , 2003, Developmental neuropsychology.

[44]  J L Bradshaw,et al.  Atypical interference of local detail on global processing in high-functioning autism and Asperger's disorder. , 2000, Journal of child psychology and psychiatry, and allied disciplines.

[45]  S. Baron-Cohen,et al.  Are people with autism and Asperger syndrome faster than normal on the Embedded Figures Test? , 1997, Journal of child psychology and psychiatry, and allied disciplines.

[46]  P. Walker,et al.  Autism and a deficit in broadening the spread of visual attention. , 2003, Journal of child psychology and psychiatry, and allied disciplines.

[47]  B. Fischer,et al.  Voluntary Saccadic Control in Dyslexia , 2000, Perception.

[48]  R. Weale Analysis of Visual Behaviour , 1983 .

[49]  F. Ramus,et al.  A double dissociation between sensorimotor impairments and reading disability: A comparison of autistic and dyslexic children , 2006, Cognitive neuropsychology.

[50]  G. Pavlidis,et al.  Do eye movements hold the key to dyslexia? , 1981, Neuropsychologia.

[51]  Marcia A. Bockbrader,et al.  Subjective Perceptual Distortions and Visual Dysfunction in Children with Autism , 2006, Journal of autism and developmental disorders.

[52]  Mark S. Seidenberg,et al.  Deficits in perceptual noise exclusion in developmental dyslexia , 2005, Nature Neuroscience.

[53]  Allan L Reiss,et al.  Investigation of neuroanatomical differences between autism and Asperger syndrome. , 2004, Archives of general psychiatry.

[54]  G. Legge,et al.  Displacement detection in human vision , 1981, Vision Research.

[55]  E H Adelson,et al.  Spatiotemporal energy models for the perception of motion. , 1985, Journal of the Optical Society of America. A, Optics and image science.

[56]  G. Mesibov,et al.  Brief report: The relationship of learning disabilities and higher-level autism , 1985, Journal of autism and developmental disorders.

[57]  B. Skottun,et al.  The magnocellular deficit theory of dyslexia: the evidence from contrast sensitivity , 2000, Vision Research.

[58]  J. Stein,et al.  VISUAL MAGNOCELLULAR IMPAIRMENT IN ADULT DEVELOPMENTAL DYSLEXICS , 1998 .

[59]  D. Regan,et al.  Defective processing of motion-defined form in the fellow eye of patients with unilateral amblyopia. , 1992, Investigative ophthalmology & visual science.

[60]  N. Rinehart,et al.  A Clinical and Neurobehavioural Review of High-Functioning Autism and Asperger's Disorder , 2002, The Australian and New Zealand journal of psychiatry.

[61]  Harold E. Bedell,et al.  The Effect of Flicker on Foveal and Peripheral Thresholds for Oscillatory Motion , 1995, Vision Research.

[62]  M. Turatto,et al.  Orienting of visual attention in dyslexia: evidence for asymmetric hemispheric control of attention , 2001, Experimental Brain Research.

[63]  W. Newsome,et al.  A selective impairment of motion perception following lesions of the middle temporal visual area (MT) , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[64]  K. Nakayama,et al.  Psychophysical isolation of movement sensitivity by removal of familiar position cues , 1981, Vision Research.

[65]  M. Goodale,et al.  The visual brain in action , 1995 .

[66]  Michael Johnston,et al.  A test of the magnocellular deficit theory of dyslexia in an adult sample , 2006, Cognitive neuropsychology.

[67]  A. Parker,et al.  Sense and the single neuron: probing the physiology of perception. , 1998, Annual review of neuroscience.

[68]  Ellen Winner,et al.  Dyslexia linked to talent: Global visual-spatial ability , 2003, Brain and Language.

[69]  H. Komatsu,et al.  Relation of cortical areas MT and MST to pursuit eye movements. II. Differentiation of retinal from extraretinal inputs. , 1988, Journal of neurophysiology.