Calcium as a coagonist of inositol 1,4,5-trisphosphate-induced calcium release.

Inositol 1,4,5-trisphosphate (IP3)-induced calcium release from intracellular stores is a regulator of cytosolic-free calcium levels. The subsecond kinetics and regulation of IP3-induced calcium-45 release from synaptosome-derived microsomal vesicles were resolved by rapid superfusion. Extravesicular calcium acted as a coagonist, potentiating the transient IP3-induced release of calcium-45. Thus, rapid elevation of cytosolic calcium levels may trigger IP3-induced calcium release in vivo. Extravesicular calcium also produced a more slowly developing, reversible inhibition of IP3-induced calcium-45 release. Sequential positive and negative feedback regulation by calcium of IP3-induced calcium release may contribute to transients and oscillations of cytosolic-free calcium in vivo.

[1]  Michael J. Berridge,et al.  Inositol phosphates and cell signalling , 1989, Nature.

[2]  Ole H. Petersen,et al.  Pulsatile intracellular calcium release does not depend on fluctuations in inositol trisphosphate concentration , 1989, Nature.

[3]  R. Tsien,et al.  Imaging of cytosolic Ca2+ transients arising from Ca2+ stores and Ca2+ channels in sympathetic neurons , 1988, Neuron.

[4]  R. Payne,et al.  Feedback inhibition by calcium limits the release of calcium by inositol trisphosphate in Limulus ventral photoreceptors , 1990, Neuron.

[5]  G. Meissner,et al.  Kinetics of rapid Ca2+ release by sarcoplasmic reticulum. Effects of Ca2+, Mg2+, and adenine nucleotides. , 1986, Biochemistry.

[6]  R. Dingledine,et al.  Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. , 1988, Science.

[7]  L. Pearce,et al.  A superfusion system designed to measure release of radiolabeled neurotransmitters on a subsecond time scale. , 1989, Analytical biochemistry.

[8]  N. Leblanc,et al.  Sodium current-induced release of calcium from cardiac sarcoplasmic reticulum. , 1990, Science.

[9]  A. Fabiato,et al.  Time and calcium dependence of activation and inactivation of calcium- induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell , 1985, The Journal of general physiology.

[10]  M. Morad,et al.  Regulation of calcium release is gated by calcium current, not gating charge, in cardiac myocytes. , 1989, Science.

[11]  T. Rink,et al.  Calcium oscillations in non-excitable cells , 1989, Trends in Neurosciences.

[12]  C. Klee,et al.  Calcium modulation of inositol 1,4,5-trisphosphate-induced calcium release from neuroblastoma x glioma hybrid (NG108-15) microsomes. , 1986, The Journal of biological chemistry.

[13]  T. Südhof,et al.  Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor , 1989, Nature.

[14]  I. Parker,et al.  Inhibition by Ca2+ of inositol trisphosphate-mediated Ca2+ liberation: a possible mechanism for oscillatory release of Ca2+. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[15]  S. M. Goldin,et al.  Multiple components of synaptosomal [3H]-gamma-aminobutyric acid release resolved by a rapid superfusion system. , 1989, Biochemistry.

[16]  L. Stryer,et al.  Kinetics of calcium channel opening by inositol 1,4,5-trisphosphate. , 1990, Biochemistry.

[17]  Teiichi Furuichi,et al.  Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400 , 1989, Nature.

[18]  T. Rink,et al.  Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells , 1988, Nature.

[19]  S H Snyder,et al.  Solubilization, purification, and characterization of an inositol trisphosphate receptor. , 1988, The Journal of biological chemistry.

[20]  M. Iino,et al.  Biphasic Ca2+ dependence of inositol 1,4,5-trisphosphate-induced Ca release in smooth muscle cells of the guinea pig taenia caeci , 1990, The Journal of general physiology.

[21]  J. Williamson,et al.  The effect of external calcium and pH on inositol trisphosphate-mediated calcium release from cerebellum microsomal fractions. , 1989, The Biochemical journal.

[22]  É. Doucet,et al.  Fast kinetics of calcium release induced by myo-inositol trisphosphate in permeabilized rat hepatocytes. , 1989, The Journal of biological chemistry.

[23]  L. Pearce,et al.  Two functionally distinct forms of guanosine cyclic 3',5'-phosphate stimulated cation channels in a bovine rod photoreceptor disk preparation. , 1988, Biochemistry.

[24]  H. Pant,et al.  Inositol trisphosphate-induced calcium release in brain microsomes , 1987, Brain Research.

[25]  A. Fabiato.  Simulated calcium current can both cause calcium loading in and trigger calcium release from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell , 1985, The Journal of general physiology.

[26]  L. Stryer,et al.  Transient calcium release induced by successive increments of inositol 1,4,5-trisphosphate. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[27]  M. Berridge,et al.  Inositol trisphosphate and diacylglycerol: two interacting second messengers. , 1987, Annual review of biochemistry.

[28]  R. Huganir,et al.  Purified inositol 1,4,5-trisphosphate receptor mediates calcium flux in reconstituted lipid vesicles , 1989, Nature.

[29]  L. Stryer,et al.  Highly cooperative opening of calcium channels by inositol 1,4,5-trisphosphate. , 1988, Science.

[30]  S. Chueh,et al.  Inositol 1,4,5-trisphosphate and guanine nucleotides activate calcium release from endoplasmic reticulum via distinct mechanisms. , 1986, The Journal of biological chemistry.