Assessment of protective potential of Nigella sativa oil against carbendazim- and/or mancozeb-induced hematotoxicity, hepatotoxicity, and genotoxicity

[1]  J. Bancroft,et al.  Bancroft's Theory and Practice of Histological Techniques , 2018 .

[2]  S. Farouk,et al.  Protective effects of ethanolic extract of rosemary against lead-induced hepato-renal damage in rabbits. , 2016, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

[3]  I. A. Adedara,et al.  6-Gingerol-Rich Fraction from Zingiber officinale Prevents Hematotoxicity and Oxidative Damage in Kidney and Liver of Rats Exposed to Carbendazim , 2016, Journal of dietary supplements.

[4]  Amit Kumar Srivastava,et al.  Protective effects of lupeol against mancozeb-induced genotoxicity in cultured human lymphocytes. , 2016, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[5]  P. Bulet,et al.  Ex vivo assessment of testicular toxicity induced by carbendazim and iprodione, alone or in a mixture. , 2016, ALTEX.

[6]  I. Dhouib,et al.  Carbamates pesticides induced immunotoxicity and carcinogenicity in human: A review , 2016 .

[7]  T. M. Saber,et al.  Curcumin ameliorates mancozeb-induced neurotoxicity in rats , 2016 .

[8]  Changhao Sun,et al.  Effect of quercetin against mixture of four organophosphate pesticides induced nephrotoxicity in rats , 2016, Xenobiotica; the fate of foreign compounds in biological systems.

[9]  Hyung-Sub Kang,et al.  Hepatoprotective effects of Nigella sativa seed extract against acetaminophen-induced oxidative stress. , 2016, Asian Pacific journal of tropical medicine.

[10]  Z. Farooqui,et al.  Oral administration of Nigella sativa oil ameliorates the effect of cisplatin on membrane enzymes, carbohydrate metabolism and oxidative damage in rat liver , 2016, Toxicology reports.

[11]  A. Rašković,et al.  Effects of pharmaceutical formulations containing thyme on carbon tetrachloride-induced liver injury in rats , 2015, BMC Complementary and Alternative Medicine.

[12]  L. Nahar,et al.  Hypoglycemic and Hypolipidemic Potential of Nigella sativa L. SeedExtract in Streptozotocin (STZ)-Induced Diabetic Rats , 2015 .

[13]  A. Majdalawieh,et al.  Immunomodulatory and anti-inflammatory action of Nigella sativa and thymoquinone: A comprehensive review. , 2015, International immunopharmacology.

[14]  V. Monsalvo.  Genotoxicity and Cytotoxicity Exerted by Pesticides in Different Biotic Matrices: An Overview of More Than a Decade of Experimental Evaluation , 2015 .

[15]  S. Ben-Shabat,et al.  Anticancer activity of Nigella sativa (black seed) and its relationship with the thermal processing and quinone composition of the seed , 2015, Drug design, development and therapy.

[16]  Ramadan Al-shdefat,et al.  Genoprotective and Genotoxic Effects of Thymoquinone on Doxorubicin-Induced Damage in Isolated Human Leukocytes , 2015 .

[17]  I. Ahmad,et al.  Neuroprotective effects of Nigella sativa extracts during germination on central nervous system , 2015 .

[18]  M. Boulakoud,et al.  Biochemical and Hematological Changes Following Long Term Exposure to Mancozeb , 2015 .

[19]  H. Hosseinzadeh,et al.  Iranian Journal of Basic Medical Sciences the Protective Effect of Nigella Sativa against Liver Injury: a Review , 2022 .

[20]  H. Hosseinzadeh,et al.  Iranian Journal of Basic Medical Sciences Black Cumin (nigella Sativa) and Its Constituent (thymoquinone): a Review on Antimicrobial Effects , 2022 .

[21]  S. Ismail,et al.  Spirulina platensis ameliorative effect against GSM 900-MHz cellular phone radiation-induced genotoxicity in male Sprague-Dawley rats , 2014, Comparative Clinical Pathology.

[22]  Sherlock,et al.  Disease of the liver and biliary system , 2014 .

[23]  S. Siddiqui.  Study on hepatic histopathological observations and the ameliorative effects of Ocimum sanctum on mancozeb induced toxicity in albino mice , 2014 .

[24]  S. Law,et al.  Pesticide induced alterations in marrow physiology and depletion of stem and stromal progenitor population: An experimental model to study the toxic effects of pesticide , 2014, Environmental toxicology.

[25]  M. Boulakoud,et al.  SUBCHRONIC MANCOZEB TREATEMENT INDUCED LIVER TOXICITY VIA OXIDATIVE STRESS IN MALE WISTAR RATS. , 2014, Communications in agricultural and applied biological sciences.

[26]  Ajay Kumar,et al.  Effect of sub-lethal doses of imidacloprid on histological and biochemical parameters in female albino mice , 2014 .

[27]  P. Ardenghi,et al.  DNA damage in Wistar rats exposed to dithiocarbamate pesticide mancozeb. , 2014, Folia biologica.

[28]  T. Motawi,et al.  Effect of simvastatin and naringenin coadministration on rat liver DNA fragmentation and cytochrome P450 activity: an in vivo and in vitro study , 2013, Journal of Physiology and Biochemistry.

[29]  O. Kujan,et al.  Antioxidant Properties of Nigella sativa , 2013 .

[30]  Mainul Haque,et al.  HEPATO-PROTECTIVE ROLE OF THE AQUEOUS AND N-HEXANE EXTRACTS OF NIGELLA SATIVA LINN. IN EXPERIMENTAL LIVER DAMAGE IN RATS , 2013 .

[31]  H. Lamfon,et al.  Protective Effect of Gingo biloba Extract on Carbendazim-Induced Hepatotoxicity in Albino Rats , 2013 .

[32]  L. Latiff,et al.  Toxicity effect of nigella sativa on the liver function of rats. , 2013, Advanced pharmaceutical bulletin.

[33]  Effect of Mancozeb on the Specific activities of Testicular Phosphatases and Protective role of Vitamin C in Albino rats , 2013 .

[34]  N. Al-Khafaji.  Protective Effect of Crude Oil of Nigella Sativa on Liver in Male Albino Mice Treated with Low Toxic Dose of Paracetamol , 2013 .

[35]  J. Danladi,et al.  Protective Effect of Cool Extraction of Black Seed (Nigella Sativa) Oil Against CCl4-Induced Oxidative Damages in Wistar Rats Testis. , 2013 .

[36]  A. Gani,et al.  EVALUTION OF HEPATOPROTECTIVE EFFECT OF NIGELLA SATIVA L. , 2013 .

[37]  B. Ahmad,et al.  Nephro-protective effect of vitamin C and Nigella sativa oil on gentamicin associated nephrotoxicity in rabbits. , 2012, Pakistan journal of pharmaceutical sciences.

[38]  Amit Kumar Srivastava,et al.  Mancozeb-induced genotoxicity and apoptosis in cultured human lymphocytes. , 2012, Life sciences.

[39]  M. Mustafa,et al.  A case control study of gene environmental interaction in fetal growth restriction with special reference to organochlorine pesticides. , 2012, European journal of obstetrics, gynecology, and reproductive biology.

[40]  G. Uggini,et al.  Embryotoxic and teratogenic effects of pesticides in chick embryos: A comparative study using two commercial formulations , 2012, Environmental toxicology.

[41]  H. Hashem.  Light and Electron Microscopic Study of the Possible Protective Effect of Nigella Sativa on Metalaxyl Induced Hepatotoxicity in Adult Albino Rats , 2012 .

[42]  V. Tsutsumi,et al.  Hepatic Effects from Subacute Exposure to Insecticides in Adult Male Wistar Rats , 2012 .

[43]  A. Dawood.  Immunomodulatory effect of Nigella sativa seed extract in male rabbits treated with dexamethasone , 2012 .

[44]  A. Hashem,et al.  Protective Effect of Curcuma longa or Nigella sativa on Aflatoxin B1- Induced Hepato-Toxicity in Rats in Relation to Food Safety on Public Health , 2012 .

[45]  Talal A. Zari,et al.  Therapeutic effects of olive leaves extract on rats treated with a sublethal concentration of carbendazim. , 2011, European review for medical and pharmacological sciences.

[46]  S. Qamar,et al.  Comparative gastroprotective effects of natural honey, Nigella sativa and cimetidine against acetylsalicylic acid induced gastric ulcer in albino rats. , 2011, Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.

[47]  P. Muthuraman,et al.  Acute Toxicological Evaluation of Low Dose Methyl 2-benzimidazole Carbamate Fungicide on Male Albino Rats , 2011 .

[48]  A. Ogbera,et al.  Complementary and alternative medicine use in diabetes mellitus. , 2011, West African journal of medicine.

[49]  R. B. Kaliwal.  Effect of Mancozeb on thyroid, testis, accessory reproductive organs and biochemical constituents in albino mice. , 2010 .

[50]  Fang Yu,et al.  Pesticide use and thyroid disease among women in the Agricultural Health Study. , 2010, American journal of epidemiology.

[51]  Ralf Hass,et al.  Cellular responses to reactive oxygen species-induced DNA damage and aging , 2008, Biological chemistry.

[52]  K. Srikumar,et al.  Toxic effects of carbendazim at low dose levels in male rats. , 2008, The Journal of toxicological sciences.

[53]  E. Kaya,et al.  Biochemical effects of chlorpyrifos and deltamethrin on altered antioxidative defense mechanisms and lipid peroxidation in rat liver , 2008, Cell biochemistry and function.

[54]  S. Govindwar,et al.  Biochemical effects of various pesticides on sprayers of grape gardens , 2003, Indian Journal of Clinical Biochemistry.

[55]  J. Ekanem,et al.  Some biochemical and haematological effects of black seed ( Nigella sativa ) oil on Trypanosoma brucei -infected rats , 2008 .

[56]  L. Costa,et al.  Neurotoxicity of pesticides: a brief review. , 2008, Frontiers in bioscience : a journal and virtual library.

[57]  N. Srinivasan,et al.  Modulation of antioxidant defense system by the environmental fungicide carbendazim in Leydig cells of rats. , 2007, Reproductive toxicology.

[58]  A. Farrag,et al.  Protective effect of Nigella sativa seeds against lead-induced hepatorenal damage in male rats. , 2007, Pakistan journal of biological sciences : PJBS.

[59]  S. Sakr.  Ameliorative Effect of Ginger (Zingiber officinale ) on Mancozeb Fungicide Induced Liver Injury in Albino Rats , 2007 .

[60]  P. Palozza,et al.  DNA damage and apoptosis induction by the pesticide Mancozeb in rat cells: involvement of the oxidative mechanism. , 2006, Toxicology and applied pharmacology.

[61]  Katalin Reisinger,et al.  Determination of carbendazim residues in the eggs, liver and pectoral muscle of Japanese quail (Coturnix coturnix japonica). , 2006, Acta veterinaria Hungarica.

[62]  S. Deresinski,et al.  Hepatotoxicity of antifungal agents. , 2005, Current opinion in investigational drugs.

[63]  B. Kaliwal,et al.  Temporal effects of mancozeb on testes, accessory reproductive organs and biochemical constituents in albino mice. , 2003, Environmental toxicology and pharmacology.

[64]  N. Pant,et al.  Testicular and spermatotoxic effects of quinalphos in rats , 2003, Journal of applied toxicology : JAT.

[65]  M. Atamanalp,et al.  Alterations in Hematological Parameters of Rainbow Trout (Oncorhynchus mykiss) Exposed to Mancozeb , 2003 .

[66]  G. Selmanoğlu,et al.  Effects of carbendazim on rat thyroid, parathyroid, pituitary and adrenal glands and their hormones , 2002, Human & experimental toxicology.

[67]  B. Kaliwal,et al.  Induction of gonadal toxicity to female rats after chronic exposure to mancozeb. , 2001, Industrial health.

[68]  K. Sitarek.  Embryolethal and teratogenic effects of carbendazim in rats. , 2001, Teratogenesis, carcinogenesis, and mutagenesis.

[69]  F. Bucar,et al.  Antioxidant activity of Nigella sativa essential oil , 2000, Phytotherapy research : PTR.

[70]  M. Lacaille‐Dubois,et al.  [Diuretic and hypotensive effects of Nigella sativa in the spontaneously hypertensive rat]. , 2000, Therapie.

[71]  A. Tamhane,et al.  Statistics and Data Analysis: From Elementary to Intermediate , 1999 .

[72]  A. Fabra,et al.  Interaction of the fungicide mancozeb and Rhizobium sp. in pure culture and under field conditions , 1997, Biology and Fertility of Soils.

[73]  M. K. Srivastava,et al.  Induction of gonadal toxicity to male rats after chronic exposure to mancozeb. , 1997, Industrial health.

[74]  S. Al-Sedairy,et al.  Nigella sativa: effect on human lymphocytes and polymorphonuclear leukocyte phagocytic activity. , 1995, Immunopharmacology.

[75]  C. Burtis.  Tietz textbook of Clinical Chemistry , 1994 .

[76]  K. Panikkar,et al.  Antitumour principles from Nigella sativa seeds. , 1992, Cancer letters.

[77]  B. Halliwell,et al.  Role of free radicals and catalytic metal ions in human disease: an overview. , 1990, Methods in enzymology.

[78]  M. Antal,et al.  Subacute toxicological examination of Dithane M-45. , 1989, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[79]  Schalm Ow,et al.  Schalm's Veterinary Hematology , 1986 .

[80]  H. Aebi,et al.  Catalase in vitro. , 1984, Methods in enzymology.

[81]  A. E. Ahmed,et al.  Acrylonitrile: in vivo cytogenetic studies in mice and rats. , 1980, Mutation research.

[82]  M. Uchiyama,et al.  Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. , 1978, Analytical biochemistry.

[83]  K. Yagi,et al.  The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen. , 1972, Biochemical and biophysical research communications.