2 Megakaryocyte function and dysfunction

[1]  K. Bendix-Hansen,et al.  Distribution of intrapulmonary megakaryocytes. , 2009, Acta pathologica et microbiologica Scandinavica. Section A, Pathology.

[2]  B. Lagerlöf,et al.  The ultrastructure of megakaryocytes in polycythaemia vera and chronic granulocytic leukaemia. , 2009, Acta pathologica et microbiologica Scandinavica. Section A, Pathology.

[3]  J. Thiele,et al.  Density distribution and size of megakaryocytes in inflammatory reactions of the bone marrow (myelitis) and chronic myeloproliferative diseases. , 2009, Scandinavian journal of haematology.

[4]  A. Berrebi,et al.  Surface features of leukaemic megakaryocytic precursors. A study of 5 cases of megakaryoblastic leukaemia with scanning electron microscopy. , 2009, Scandinavian journal of haematology.

[5]  M. Chilosi,et al.  Detection of normal and malignant megakaryocytes by anti beta-thromboglobulin serum. An immunofluorescence study. , 2009, Scandinavian journal of haematology.

[6]  N. T. Pedersen,et al.  Circulating megakaryocytes in patients with pulmonary inflammation and in patients subjected to cholecystectomy. , 2009, Scandinavian journal of haematology.

[7]  A. Popławski,et al.  Abnormalities of platelet function and ultrastructure in macrothrombocytic thrombopathia. , 2009, Scandinavian journal of haematology.

[8]  N. T. Pedersen Occurrence of megakaryocytes in various vessels and their retention in the pulmonary capillaries in man. , 2009, Scandinavian journal of haematology.

[9]  Z. Fuks,et al.  Role of Heparanase in Platelet and Tumor Cell Interactions with the Subendothelial Extracellular Matrix , 1987, Seminars in thrombosis and hemostasis.

[10]  L. Vannucchi,et al.  Megakaryocyte progenitors in the bone marrow and peripheral blood of patients with myeloproliferative diseases , 1987, American journal of hematology.

[11]  L. Corash,et al.  Regulation of thrombopoiesis: effects of the degree of thrombocytopenia on megakaryocyte ploidy and platelet volume. , 1987, Blood.

[12]  R. Rosenberg,et al.  In vitro stimulation of megakaryocyte maturation by megakaryocyte stimulatory factor. , 1987, The Journal of biological chemistry.

[13]  R. Rosenberg,et al.  Purification and properties of a megakaryocyte stimulatory factor present both in the serum-free conditioned medium of human embryonic kidney cells and in thrombocytopenic plasma. , 1987, The Journal of biological chemistry.

[14]  G. Crabtree,et al.  Expression of the fibrinogen genes in rat megakaryocytes. , 1986, Biochemical and biophysical research communications.

[15]  I. Talbot,et al.  Pulmonary megakaryocytes: "missing link" between cardiovascular and respiratory disease? , 1986, Journal of clinical pathology.

[16]  M. Sacchetti,et al.  Cell-mediated suppression of megakaryocytopoiesis in acquired amegakaryocytic thrombocytopenic purpura. , 1986, Blood.

[17]  M. Tomonaga,et al.  Diagnostic significance of detecting pseudo‐Pelger‐Huet anomalies and micro‐megakaryocytes in myelodysplastic syndrome , 1986, British journal of haematology.

[18]  R. Colman,et al.  Biology of human megakaryocyte factor V. , 1986, Blood.

[19]  R. Hoffman,et al.  Transitory hypomegakaryocytic thrombocytopenia: aetiological association with ethanol abuse and implications regarding regulation of human megakaryocytopoiesis , 1986, British journal of haematology.

[20]  J. Spivak,et al.  Effect of ethanol on thrombopoiesis , 1986, British journal of haematology.

[21]  T. McDonald,et al.  Incomplete antigenic cross-reactivity between platelets and megakaryocytes: relevance to ITP. , 1986, Blood.

[22]  T. Nagasawa,et al.  Cell-mediated amegakaryocytic thrombocytopenia associated with systemic lupus erythematosus. , 1986, Blood.

[23]  Ann Lee,et al.  Biosynthesis of von Willebrand protein by human megakaryocytes. , 1985, The Journal of clinical investigation.

[24]  Z. Fuks,et al.  Megakaryocyte interaction with subendothelial extracellular matrix is associated with adhesion, platelet-like shape change, and thromboxane A2 production , 1985 .

[25]  K. Mann,et al.  Identification of human megakaryocyte coagulation factor V. , 1985, Blood.

[26]  Z. Fuks,et al.  Platelet interaction with subendothelial extracellular matrix: platelet-fibrinogen interactions are essential for platelet aggregation but not for the matrix-induced release reaction. , 1985, Blood.

[27]  R. Hoffman,et al.  Purification and partial characterization of a megakaryocyte colony-stimulating factor from human plasma. , 1985, The Journal of clinical investigation.

[28]  R. Leven,et al.  Fibrinogen biosynthesis in isolated guinea pig megakaryocytes , 1985 .

[29]  D. Slater,et al.  THE PLATELET IN ASTHMA , 1985, The Lancet.

[30]  T. Koike Megakaryoblastic leukemia: the characterization and identification of megakaryoblasts. , 1984, Blood.

[31]  J. Katzmann,et al.  Acute leukemia with megakaryocytic differentiation: a study of 12 cases identified immunocytochemically. , 1984, Blood.

[32]  D. Slater,et al.  The origin of platelet count and volume. , 1984, Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics.

[33]  P. Hasleton,et al.  Quantitation of pulmonary megakaryocytes and fibrin thrombi in patients dying from burns , 1984, Histopathology.

[34]  R. Nachman,et al.  Human megakaryocytes. III. Characterization in myeloproliferative disorders. , 1984, Blood.

[35]  Nachmias Vt Platelet and megakaryocyte shape change: triggered alterations in the cytoskeleton. , 1983 .

[36]  J. Martin,et al.  Changes in volume and density of platelets in myocardial infarction. , 1983, British medical journal.

[37]  P. Hasleton Adult respiratory distress syndrome—a review , 1983, Histopathology.

[38]  G. Dahl,et al.  Relationship of megakaryocyte size at diagnosis to chemotherapeutic response in children with acute nonlymphocytic leukemia. , 1983, Blood.

[39]  J. Miller,et al.  Characterization of the megakaryocyte secretory response: studies of continuously monitored release of endogenous ATP. , 1983, Blood.

[40]  D. Slater,et al.  ABNORMAL INTRAPULMONARY PLATELET PRODUCTION: A POSSIBLE CAUSE OF VASCULAR AND LUNG DISEASE , 1983, The Lancet.

[41]  D. Catovsky,et al.  Reversal of marrow fibrosis in acute megakaryoblastic leukaemia after remission‐induction and consolidation chemotherapy followed by bone marrow transplantation , 1983, British journal of haematology.

[42]  F. Patrone,et al.  A monoclonal antibody to platelet glycoproteins IIb and IIIa complex: its use in purifying human megakaryocytes from sternal bone marrow aspirates for immunofluorescence studies of Ia-like antigens. , 1983, Experimental hematology.

[43]  K. Mclaren Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets. , 1983, Journal of clinical pathology.

[44]  R. Hoffman,et al.  In vitro studies of megakaryocytopoiesis in thrombocytotic disorders of man. , 1983, Blood.

[45]  J. Radley,et al.  Fate of senescent megakaryocytes in the bone marrow , 1983, British journal of haematology.

[46]  A. Nakeff,et al.  New synthesis of a platelet-specific protein: platelet factor 4 synthesis in a megakaryocyte-enriched rabbit bone marrow culture system , 1983, The Journal of cell biology.

[47]  D. Slater,et al.  Evidence for a theory of physical fragmentation of megakaryocytes, implying that all platelets are produced in the pulmonary circulation. , 1982, Thrombosis research.

[48]  F. Booyse,et al.  Culture-produced subendothelium. II. Effect of plasma, F.VIIIR:WF and fibronectin on interaction of normal platelets with normal and von Willebrand porcine aortic subendothelium. , 1982, Thrombosis research.

[49]  R. Hoffman,et al.  Acquired amegakaryocytic thrombocytopenic purpura: a syndrome of diverse etiologies. , 1982, Blood.

[50]  R. Levine,et al.  The significance of megakaryocyte size. , 1982, Blood.

[51]  Z. Fuks,et al.  Platelet interaction with the extracellular matrix produced by cultured endothelial cells: a model to study the thrombogenicity of isolated subendothelial basal lamina. , 1982, Thrombosis research.

[52]  N. Williams,et al.  Annotation: THE ORIGIN, DEVELOPMENT AND REGULATION OF MEGAKARYOCYTES , 1982 .

[53]  M. Long,et al.  Immature megakaryocytes in the mouse: In vitro relationship to megakaryocyte progenitor cells and mature megakaryocytes , 1982, Journal of cellular physiology.

[54]  J. Miller,et al.  Arachidonic acid metabolism in guinea pig megakaryocytes. , 1982, Biochemical and biophysical research communications.

[55]  J. Radley,et al.  The demarcation membrane system of the megakaryocyte: a misnomer? , 1982, Blood.

[56]  A. McMichael,et al.  Megakaryocyte cultures in the chronic phase and in the blast crisis of chronic myeloid leukaemia: studies on the differentiation of the megakaryocyte progenitors and on the maturation of megakaryocytes in vitro , 1982, British journal of haematology.

[57]  M. Long,et al.  Immature megakaryocytes in the mouse: physical characteristics, cell cycle status, and in vitro responsiveness to thrombopoietic stimulatory factor. , 1982, Blood.

[58]  V. Nachmias,et al.  Cultured megakaryocytes: changes in the cytoskeleton after ADP-induced spreading , 1982, The Journal of cell biology.

[59]  D. J. Nelson,et al.  Two‐factor requirement for murine megakaryocyte colony formation , 1982, Journal of cellular physiology.

[60]  M. Long,et al.  Immature Megakaryocytes in the Mouse: Morphology and quantitation by acetylcholinesterase staining. , 1981, Blood.

[61]  M. Weinstein,et al.  A marker for megakaryocytes: serotonin accumulation in guinea pig megakaryocytes. , 1981, The Journal of laboratory and clinical medicine.

[62]  A. Nakeff,et al.  Thromboxane synthesis in megakaryocytes isolated by centrifugal elutriation. , 1981, Blood.

[63]  Leung,et al.  Human megakaryocytes. II. Expression of platelet proteins in early marrow megakaryocytes , 1981, The Journal of experimental medicine.

[64]  G. Scurfield,et al.  Aspects of platelet formation and release , 1981, American journal of hematology.

[65]  M. Tavassoli,et al.  Migration of Entire Megakaryocytes through the Marrow‐Blood Barrier , 1981, British journal of haematology.

[66]  J. Breton‐Gorius ON THE ALLEGED PHAGOCYTOSIS BY MEGAKARYOCYTES , 1981, British journal of haematology.

[67]  A. Yen,et al.  Human megakaryocyte stimulation of proliferation of bone marrow fibroblasts. , 1981, Blood.

[68]  B. Schick,et al.  Lipid composition of guinea pig platelets and megakaryocytes. The megakaryocyte as a probable source of platelet lipids. , 1981, Biochimica et biophysica acta.

[69]  B. Schick,et al.  Cholesterol and phospholipid biosynthesis in guinea pig megakaryocytes. , 1981, Biochimica et biophysica acta.

[70]  G. Scurfield,et al.  The mechanism of platelet release. , 1980, Blood.

[71]  D. Gospodarowicz,et al.  Growth factors and the extracellular matrix. , 1980, Endocrine reviews.

[72]  R. Levine Isolation and Characterization of Normal Human Megakaryocytes , 1980, British journal of haematology.

[73]  D. Goodman,et al.  Origin of platelet-derived growth factor in megakaryocytes in guinea pigs. , 1980, The Journal of clinical investigation.

[74]  P. Fishman,et al.  SEM Observations on the Mechanism of Platelet Release from Megakaryocytes , 1979, Thrombosis and Haemostasis.

[75]  J. Levin,et al.  Partial purification of thrombopoietin from the plasma of thrombocytopenic rabbits , 1979 .

[76]  O. Myhre-Jensen,et al.  RESPONSE OF PULMONARY (CIRCULATING) MEGAKARYOCYTES TO EXPERIMENTALLY INDUCED CONSUMPTION COAGULOPATHY IN RABBITS , 1979, Acta pathologica et microbiologica Scandinavica. Section A, Pathology.

[77]  R. Winchester,et al.  Human megakaryocytes. I. Characterization of the membrane and cytoplasmic components of isolated marrow megakaryocytes , 1979, The Journal of experimental medicine.

[78]  J. Paulus,et al.  Control of platelet territory development in megakaryocytes. , 1979, Blood cells.

[79]  E. Jaffe,et al.  Synthesis of actin by cultured guinea pig megakaryocytes. Complex formation with fibrin. , 1978, Biochimica et biophysica acta.

[80]  R. Mcmillan,et al.  Antibody against megakaryocytes in idiopathic thrombocytopenic purpura. , 1978, JAMA.

[81]  L. Kass,et al.  Megakaryocytes in the Giant Platelet Syndrome , 1977, Thrombosis and Haemostasis.

[82]  E. Jaffe,et al.  Synthesis of factor VIII antigen by cultured guinea pig megakaryocytes. , 1977, The Journal of clinical investigation.

[83]  Fedorko Me The functional capacity of guinea pig megakaryocytes. I. Uptake of 3H-serotonin by megakaryocytes and their physiologic and morphologic response to stimuli for the platelet release reaction. , 1977 .

[84]  J. Levin,et al.  Relationships between thrombopoiesis and erythropoiesis: with studies of the effects of preparations of thrombopoietin and erythropoietin , 1976 .

[85]  R. Levine,et al.  Isolation of intact megakaryocytes from guinea pig femoral marrow. Successful harvest made possible with inhibitions of platelet aggregation; enrichment achieved with a two-step separation technique , 1976, The Journal of cell biology.

[86]  J. Kutti,et al.  Platelet Survival and Platelet Production in Idiopathic Thrombocytopenic Purpura (ITP) , 1974, British journal of haematology.

[87]  C. Kuhn,et al.  Viral infection of megakaryocytes in varicella with purpura. , 1974, American journal of clinical pathology.

[88]  G. Brecher,et al.  Atypical megakaryocytes in preleukemic phase of acute myeloid leukemia. , 1973, Blood.

[89]  R. Wagner,et al.  DEMONSTRATION OF FACTOR XIII IN HUMAN MEGAKARYOCYTES BY A FLUORESCENT ANTIBODY TECHNIQUE * , 1972, Annals of the New York Academy of Sciences.

[90]  C. Sultan,et al.  Identification of circulating micromegakaryocytes in a case of refractory anemia: an electron microscopic-cytochemical study. , 1972, Blood.

[91]  G. Macpherson Origin and development of the demarcation system in megakaryocytes of rat bone marrow. , 1972, Journal of ultrastructure research.

[92]  L. Kilham,et al.  Rat virus infection of megakaryocytes: a factor in hemorrhagic encephalopathy? , 1972, Experimental and molecular pathology.

[93]  B. Lagerlöf Cytophotometric study of megakaryocyte ploidy in polycythemia vera and chronic granulocytic leukemia. , 1972, Acta cytologica.

[94]  M. da Prada,et al.  STORAGE OF 5-HYDROXYTRYPTAMINE IN MEGAKARYOCYTES , 1972, The Journal of cell biology.

[95]  J. White Serotonin storage organelles in human megakaryocytes. , 1971, The American journal of pathology.

[96]  W. Queisser,et al.  Polyploidization of Megakaryocytes in Normal Humans, in Patients with Idiopathic Thrombocytopenia and with Pernicious Anaemia , 1971, British journal of haematology.

[97]  G. Macpherson Development of megakaryocytes in bone marrow of the rat: an analysis by electron microscopy and high resolution autoradiography , 1971, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[98]  L. Harker Thrombokinetics in Idiopathic Thrombocytopenic Purpura * , 1970, British journal of haematology.

[99]  D. Penington,et al.  Megakaryocytes in States of Altered Platelet Production: Cell Numbers, Size and DNA Content , 1970, British journal of haematology.

[100]  P. Griner,et al.  Amegakaryocytic thrombocytopenia in systemic lupus erythematosus. , 1970, Archives of internal medicine.

[101]  O. Behnke An electron microscope study of the megacaryocyte of the rat bone marrow. I. The development of the demarcation membrane system and the platelet surface coat. , 1968, Journal of ultrastructure research.

[102]  L. Harker,et al.  Kinetics of thrombopoiesis. , 1968, The Journal of clinical investigation.

[103]  A. Kuramoto,et al.  Histochemical demonstration of 5-hydroxytryptamine in platelets and megakaryocytes. , 1967, Blood.

[104]  M. Melamed,et al.  THE MEGAKARYOCYTE BLOOD COUNT , 1966, The American journal of the medical sciences.

[105]  W. Crosby,et al.  Circulating megakaryocytes and platelet release in the lung. , 1965, Blood.

[106]  L. H. Dennis,et al.  Thrombocytopenia induced by the Friend leukemia virus. , 1965, Journal of the National Cancer Institute.

[107]  W. Crosby,et al.  ORIGIN OF PULMONARY MEGAKARYOCYTES. , 1965, Blood.

[108]  R. A. Malmgren,et al.  QUANTITATIVE OBSERVATIONS OF CIRCULATING MEGAKARYOCYTES IN THE BLOOD OF PATIENTS WITH CANCER. , 1964, The New England journal of medicine.

[109]  J. Lewis,et al.  Immunocytochemical studies on platelets. The demonstration of a common antigen in human platelets and megakaryocytes. , 1960, Blood.

[110]  J. G. Sharnoff Increased pulmonary megakaryocytes; probable role in postoperative thromboembolism. , 1959, Journal of the American Medical Association.

[111]  Sharnoff Jg,et al.  Evaluation of pulmonary megakaryocytes. , 1958 .

[112]  D. Nelken,et al.  Studies on Thrombopoiesis , 1957 .

[113]  M. Stefanini,et al.  Studies on platelets. X. Morphologic characteristics of megakaryocytes by phase contrast microscopy in normals and in patients with idiopathic thrombocytopenic purpura. , 1953, Blood.

[114]  J. Kernohan,et al.  Megakaryocytes in the pulmonary capillaries. , 1952, American journal of clinical pathology.

[115]  E. Smith,et al.  The incidence, distribution and significance of Megakaryocytes in normal and diseased human tissues. , 1952, Blood.

[116]  R. Brill,et al.  The frequency of megakaryocytes in autopsy sections. , 1948, Blood.

[117]  W. H. Howell,et al.  THE PRODUCTION OF BLOOD PLATELETS IN THE LUNGS , 1937, The Journal of experimental medicine.

[118]  W. Brown,et al.  THE HISTOGENESIS OF BLOOD PLATELETS , 1913, The Journal of experimental medicine.

[119]  J. H. Wright The Origin and Nature of the Blood Plates , 1906 .

[120]  Levine Rf,et al.  Elutriation for isolation of megakaryocytes. , 1989 .

[121]  M. Bryckaert,et al.  Megakaryocytes and myelofibrosis in gray platelet syndrome. , 1987, Nouvelle revue francaise d'hematologie.

[122]  R. Stromberg,et al.  THE EFFECT OF FLOW ON THE INTERACTION OF ISOLATED MEGAKARYOCYTES WITH EXTRACELLULAR MATRIX , 1987, Thrombosis and Haemostasis.

[123]  T. McDonald,et al.  Further studies on the purification and assay of thrombopoietin. , 1986, Progress in clinical and biological research.

[124]  D. Slater,et al.  Evidence that platelets are produced in the pulmonary circulation by a physical process. , 1986, Progress in clinical and biological research.

[125]  A. Polliack,et al.  Adhesion, spreading and fragmentation of human megakaryocytes exposed to subendothelial extracellular matrix: a scanning electron microscopy study. , 1986, Scanning electron microscopy.

[126]  R. Levine 11 – Megakaryocyte Biochemistry* , 1986 .

[127]  J. Ihle,et al.  The Effect of Interleukin 3 and GM-CSA-2 on Megakaryocyte and Myeloid Clonal Colony Formation , 1985 .

[128]  Radley Jm,et al.  Time-lapse cinemicrography and scanning electron microscopy of platelet formation by megakaryocytes. , 1983 .

[129]  F. Booyse,et al.  Culture-Produced Subendothelium , 1982 .

[130]  F. Reyes,et al.  Myelofibrosis and acute megakaryoblastic leukemia in a child: topographic relationship between fibroblasts and megakaryocytes with an alpha-granule defect. , 1982, Leukemia research.

[131]  L. Rubin,et al.  Influence of prostaglandin synthesis inhibitors on pulmonary vasodilatory effects of hydralazine in dogs with hypoxic pulmonary vasoconstriction. , 1981, The Journal of clinical investigation.

[132]  W. Vainchenker,et al.  Defective alpha-granule production in megakaryocytes from gray platelet syndrome: ultrastructural studies of bone marrow cells and megakaryocytes growing in culture from blood precursors. , 1981, The American journal of pathology.

[133]  P. Ralph,et al.  Cell interactions influencing murine marrow megakaryocytes: nature of the potentiator cell in bone marrow. , 1981, Blood.

[134]  Barnhart Mi,et al.  Megakaryocytes in the lung after thrombin initiated diffuse microthrombosis: a preliminary report on ultrastructure. , 1979 .

[135]  W. Queisser,et al.  Megakaryocyte polyploidization in May-Hegglin anomaly. , 1978, Acta haematologica.

[136]  M. Lichtman,et al.  Parasinusoidal location of megakaryocytes in marrow: A determinant of platelet release , 1978, American journal of hematology.

[137]  Crosby Wh Normal platelet numbers. Pulmonary-platelet interactions. , 1975 .

[138]  O. Behnke An electron microscope study of the rat megacaryocyte. II. Some aspects of platelet release and microtubules. , 1969, Journal of ultrastructure research.

[139]  W. Dameshek,et al.  The megakaryocytes in idiopathic thrombocytopenic purpura, a form of hypersplenism. , 1946, Blood.