Gaps in glaucoma care: a systematic review of monoscopic disc photos to screen for glaucoma

One important gap in glaucoma care is the lack of an optimized screening protocol for detecting glaucoma on a population level. A systematic review of the literature was conducted to evaluate the effectiveness of monoscopic disc photos as a screening tool for detecting glaucoma. Six studies met inclusion and exclusion criteria out of 221 possible titles. The specificity of monoscopic photos to detect glaucoma compared to clinical exam was excellent (93.6–100%), while the sensitivity was much lower (50–67.4%). Monoscopic disc photos are highly specific in identifying glaucoma, though additional testing, such as perimetry, may be needed to improve their sensitivity. Further research is needed to evaluate whether monoscopic disc photos are a cost–effective way to screen for glaucoma in a primary care setting utilizing new technological advances in ophthalmic imaging such as portable non-mydriatic fundus cameras.

[1]  P. Lichter Variability of expert observers in evaluating the optic disc. , 1976, Transactions of the American Ophthalmological Society.

[2]  A. Sommer,et al.  Racial variations in the prevalence of primary open-angle glaucoma. The Baltimore Eye Survey. , 1991, JAMA.

[3]  A. Robin,et al.  Attacking the backlog of India's curable blind. The Aravind Eye Hospital model. , 1994, Archives of ophthalmology.

[4]  H. Quigley Number of people with glaucoma worldwide. , 1996, The British journal of ophthalmology.

[5]  D M Marcus,et al.  Telemedicine diagnosis of eye disorders by direct ophthalmoscopy. A pilot study. , 1998, Ophthalmology.

[6]  C J Barry,et al.  Evaluation of a portable fundus camera for use in the teleophthalmologic diagnosis of glaucoma. , 1999, Journal of glaucoma.

[7]  K. Yogesan,et al.  Software for 3-D visualization/analysis of optic-disc images , 1999, IEEE Engineering in Medicine and Biology Magazine.

[8]  B. Prum,et al.  The advanced glaucoma intervention study (AGIS): 7. the relationship between control of intraocular pressure and visual field deterioration , 2000 .

[9]  B. Prum,et al.  The advanced glaucoma intervention study (AGIS): 7. the relationship between control of intraocular pressure and visual field deterioration , 2000 .

[10]  R. Klein,et al.  The prevalence of glaucoma in a population-based study of Hispanic subjects: Proyecto VER. , 2001, Archives of ophthalmology.

[11]  E. E. Hartmann,et al.  The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. , 2002, Archives of ophthalmology.

[12]  P. Foster,et al.  The definition and classification of glaucoma in prevalence surveys , 2002, The British journal of ophthalmology.

[13]  M. C. Leske,et al.  Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial. , 2003, Archives of ophthalmology.

[14]  Cost analysis of glaucoma-related-blindness in Europe , 2005 .

[15]  Evelyn P Whitlock,et al.  Screening for Primary Open-Angle Glaucoma in the Primary Care Setting: An Update for the US Preventive Services Task Force , 2005, The Annals of Family Medicine.

[16]  H. Quigley,et al.  The number of people with glaucoma worldwide in 2010 and 2020 , 2006, British Journal of Ophthalmology.

[17]  Philip P. Chen,et al.  A multicenter, retrospective pilot study of resource use and costs associated with severity of disease in glaucoma. , 2006, Archives of ophthalmology.

[18]  Miika Linna,et al.  Cost effectiveness and cost utility of an organized screening programme for glaucoma. , 2007, Acta ophthalmologica Scandinavica.

[19]  Max Bulsara,et al.  Glaucoma screening: analysis of conventional and telemedicine‐friendly devices , 2007, Clinical & experimental ophthalmology.

[20]  Felipe A Medeiros,et al.  How should diagnostic tests be evaluated in glaucoma? , 2007, British Journal of Ophthalmology.

[21]  Jost B Jonas,et al.  Frequency-doubling threshold perimetry in predicting glaucoma in a population-based study: The Beijing Eye Study. , 2007, Archives of ophthalmology.

[22]  A. Iwase,et al.  Performance of frequency-doubling technology perimetry in a population-based prevalence survey of glaucoma: the Tajimi study. , 2007, Ophthalmology.

[23]  C. Ramsay,et al.  Screening tests for detecting open-angle glaucoma: systematic review and meta-analysis. , 2008, Investigative ophthalmology & visual science.

[24]  Gwénolé Quellec,et al.  Automated early detection of diabetic retinopathy. , 2010, Ophthalmology.

[25]  D. Pascolini,et al.  Global estimates of visual impairment: 2010 , 2011, British Journal of Ophthalmology.

[26]  A. Greene,et al.  Developing the clinical components of a complex intervention for a glaucoma screening trial: a mixed methods study , 2011, BMC medical research methodology.

[27]  S. Khanal,et al.  A population-based survey of the prevalence and types of glaucoma in Nepal: the Bhaktapur Glaucoma Study. , 2012, Ophthalmology.

[28]  D. Schopflocher,et al.  Development of a quality appraisal tool for case series studies using a modified Delphi technique , 2012 .

[29]  B. Bengtsson,et al.  Lifetime risk of blindness in open-angle glaucoma. , 2013, American journal of ophthalmology.

[30]  V. Moyer,et al.  Screening for Glaucoma: U.S. Preventive Services Task Force Recommendation Statement , 2013, Annals of Internal Medicine.

[31]  R. P. Mills,et al.  Glaucoma Screening: Current Perspectives and Future Directions , 2013, Seminars in ophthalmology.

[32]  B. Bengtsson,et al.  Prevalence and severity of undetected manifest glaucoma: results from the early manifest glaucoma trial screening. , 2013, Ophthalmology.

[33]  April Y Maa,et al.  A novel tele-eye protocol for ocular disease detection and access to eye care services. , 2014, Telemedicine journal and e-health : the official journal of the American Telemedicine Association.

[34]  G. Cioffi,et al.  A comparative effectiveness analysis of visual field outcomes after projected glaucoma screening using SD-OCT in African American communities. , 2014, Investigative ophthalmology & visual science.

[35]  Y MaaApril,et al.  A Novel Tele-Eye Protocol for Ocular Disease Detection and Access to Eye Care Services , 2014 .

[36]  E. O'Neill,et al.  Glaucomatous optic neuropathy evaluation (GONE) project: the effect of monoscopic versus stereoscopic viewing conditions on optic nerve evaluation. , 2014, American journal of ophthalmology.

[37]  D. Hodge,et al.  Long-term trends in glaucoma-related blindness in Olmsted County, Minnesota. , 2014, Ophthalmology.