Dynamic multiple beads manipulation on x-y-z directions

The use of diffractive optical elements (DOEs) for multiple trapping of dielectric micro-spheres immersed in a fluid has been demonstrated recently. When the DOEs are implemented on a spatial light modulator (SLM), the trapped particles can be independently moved by changing the configuration of the DOE. In this paper we demonstrate phase DOEs implemented on an optical addressable SLM to move an array of trapped particles in a volume of about 20x20x6 μm. Experimental results show the usefulness of this technique for particle micromanipulation in biology.

[1]  K. Dholakia,et al.  Optical micromanipulation using a Bessel light beam , 2001 .

[2]  Michael P. MacDonald,et al.  Optical Tweezers: the next generation , 2002 .

[3]  D. Cojoc,et al.  Diffractive optical elements for differential interference contrast x-ray microscopy. , 2003, Optics express.

[4]  G. G. Stokes.  "J." , 1890, The New Yale Book of Quotations.

[5]  Johannes Courtial,et al.  3D manipulation of particles into crystal structures using holographic optical tweezers. , 2004, Optics express.

[6]  D. Grier.  A revolution in optical manipulation , 2003, Nature.

[7]  Dan Cojoc,et al.  Design and fabrication of diffractive optical elements for optical tweezer arrays by means of e-beam lithography , 2002 .

[8]  S. Chu,et al.  Observation of a single-beam gradient force optical trap for dielectric particles. , 1986, Optics letters.

[9]  G. Spalding,et al.  Computer-generated holographic optical tweezer arrays , 2000, cond-mat/0008414.

[10]  H. Tiziani,et al.  Multi-functional optical tweezers using computer-generated holograms , 2000 .

[11]  A. Ashkin,et al.  Optical trapping and manipulation of viruses and bacteria. , 1987, Science.

[12]  M. Mansuripur.  Classical Optics and its Applications , 2002 .

[13]  D. Cojoc,et al.  Dynamic multiple optical trapping by means of diffractive optical elements , 2004 .

[14]  A. Ashkin.  Acceleration and trapping of particles by radiation pressure , 1970 .

[15]  Steven M. Block,et al.  Optical trapping of metallic Rayleigh particles. , 1994, Optics letters.

[16]  Norman R. Heckenberg,et al.  Optical Particle Trapping with Higher-order Doughnut Beams Produced Using High Efficiency Computer Generated Holograms , 1995 .

[17]  H. Misawa,et al.  Pattern formation and flow control of fine particles by laser-scanning micromanipulation. , 1991, Optics letters.