Hepatitis B infection in a day school for mentally retarded students: transmission from students to staff.

We carried out a seroepidemiologic study to evaluate the transmission of hepatitis B virus (HBV) from students to staff in a day school for mentally retarded students. Of 505 students tested, 37 (7.3 per cent) had HBsAg; 74 per cent of HBsAg-positive sera tested were HBeAg-positive. Of 162 staff members tested, 21 (13.0 per cent) were HBV marker positive and two (1.2 per cent) had HBsAg; specialized educators and teachers showed the highest HBV marker prevalence (22.2 per cent and 21.3 per cent, respectively). The prevalence of HBV markers among staff was independently associated with classroom contact with a HBsAg-positive student, duration of employment at the school, and previous work with mentally retarded individuals. The incidence of HBV infection among teaching staff with regular classroom contact, estimated by logistic regression analysis, was 2.6 per cent per year. This observation indicates that teaching staff in schools for mentally retarded students with direct classroom contact may carry an occupational risk of HBV infection.

[1]  M. Kane,et al.  Hepatitis B virus transmission in a public school: effects of mentally retarded HBsAG carrier students. , 1987, American journal of public health.

[2]  C. Crumpacker,et al.  A multivariate analysis of risk factors for hepatitis B virus infection among hospital employees screened for vaccination. , 1984, American journal of epidemiology.

[3]  G. Storch,et al.  Survey of hepatitis B viral markers at a public day school and a residential institution sharing mentally handicapped students. , 1984, The Journal of infectious diseases.

[4]  S. Hadler,et al.  Epidemiological analysis of the significance of low-positive test results for antibody to hepatitis B surface and core antigens , 1984, Journal of clinical microbiology.

[5]  M. Oxman Hepatitis B vaccination of high-risk hospital personnel. , 1984, Anesthesiology.

[6]  H. Hull,et al.  Hepatitis B, hepatitis B vaccine and education for the handicapped. , 1983, Pediatric infectious disease.

[7]  E. Schiff,et al.  An institutional outbreak of hepatitis B related to a human biting carrier. , 1982, The Journal of infectious diseases.

[8]  A. Mulley,et al.  Indications for use of hepatitis B vaccine, based on cost-effectiveness analysis. , 1982, The New England journal of medicine.

[9]  R. Dodd,et al.  Specificity of an assay for antibodies to hepatitis B surface antigen , 1982, Transfusion.

[10]  J. Oleske,et al.  Transmission of hepatitis B in a classroom setting. , 1980, The Journal of pediatrics.

[11]  H. Polesky,et al.  AABB-CAP survey data on hepatitis--incidence, surveillance, and prevention. , 1980, American journal of clinical pathology.

[12]  J. Marr,et al.  Deinstitutionalized mentally retarded hepatitis-B surface antigen carriers in public school classes: a descriptive study. , 1980, American journal of public health.

[13]  J. Marr,et al.  Mentally retarded hepatitis-B surface antigen carriers in NYC public school classes: a public health dilemma. , 1980, American journal of public health.

[14]  K. Goel,et al.  Hepatitis B in the school environment. , 1978, British medical journal.

[15]  B. Larke,et al.  Transmission of hepatitis B by a human bite: an occupational hazard. , 1976, Canadian Medical Association journal.

[16]  W. Szmuness,et al.  The epidemiology of serum hepatitis (SH) infections: a controlled study in two closed institutions. , 1971, American journal of epidemiology.