Feature Extraction in Sit-to-Stand Task Using M-IMU Sensors and Evaluatiton in Parkinson's Disease

This work proposes a broad analysis for the de-tection of the most relevant features for the sit-to-stand task analysis, in Parkinson's disease (PD) patients and healthysubjects (H). A group of sixteen PD patients and thirteen H subjects have been analyzed, using one magneto-inertial sensor, while the physician administers the UPDRS clinical scale. The PD group has been examined before and after thepharmacological therapy (respectively, OFF and ON phase), in order to monitor the different states of the PD, which implies changes in motor control. By calculating the features of this task, it has been possible to choose the most reliable indexes, already used in this task in order to identify differences in the score assigned through sensors. In addition to that, it has also been possible to find differences in the features' values which the clinical scale and the physician cannotidentify. Our study highlights how wearable motion sensors can detect statistically significant differences between OFF/ON phase and H subjects that the clinical evaluation can not. We conclude that our method provides a deep analysis of the sit-to-stand task with only one M-IMU, allowing to check PD patient status,providing a method for home care monitoring.

[1]  A. Bonnet [The Unified Parkinson's Disease Rating Scale]. , 2000, Revue neurologique.

[2]  Domenico Formica,et al.  A New Calibration Methodology for Thorax and Upper Limbs Motion Capture in Children Using Magneto and Inertial Sensors , 2014, Sensors.

[3]  G. M. Shambes,et al.  Biomechanical analysis of the sit-to-stand motion in elderly persons. , 1992, Archives of physical medicine and rehabilitation.

[4]  Kamiar Aminian,et al.  Ambulatory system for human motion analysis using a kinematic sensor: monitoring of daily physical activity in the elderly , 2003, IEEE Transactions on Biomedical Engineering.

[5]  Stéphane Mallat,et al.  A Theory for Multiresolution Signal Decomposition: The Wavelet Representation , 1989, IEEE Trans. Pattern Anal. Mach. Intell..

[6]  Emiliano Schena,et al.  Smart Textile Based on 12 Fiber Bragg Gratings Array for Vital Signs Monitoring , 2017, IEEE Sensors Journal.

[7]  A. Lees,et al.  Parkinson's Disease Society Brain Bank, London: overview and research. , 1993, Journal of neural transmission. Supplementum.

[8]  Kamiar Aminian,et al.  An ambulatory system for physical activity monitoring in elderly , 2000, 1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451).

[9]  L. Nyberg,et al.  Patient falls in stroke rehabilitation. A challenge to rehabilitation strategies. , 1995, Stroke.

[10]  A. Lang,et al.  Parkinson's disease. Second of two parts. , 1998, The New England journal of medicine.

[11]  Etienne Burdet,et al.  On the analysis of movement smoothness , 2015, Journal of NeuroEngineering and Rehabilitation.

[12]  Wim G. M. Janssen,et al.  Determinants of the sit-to-stand movement: a review. , 2002, Physical therapy.

[13]  Kamiar Aminian,et al.  Measurement of stand-sit and sit-stand transitions using a miniature gyroscope and its application in fall risk evaluation in the elderly , 2002, IEEE Transactions on Biomedical Engineering.

[14]  M. Hoehn,et al.  Parkinsonism , 1967, Neurology.

[15]  P H Veltink,et al.  Detection of static and dynamic activities using uniaxial accelerometers. , 1996, IEEE transactions on rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society.

[16]  Fabrizio Vecchio,et al.  Quantitative Analysis of Bradykinesia and Rigidity in Parkinson’s Disease , 2018, Front. Neurol..

[17]  Etienne Burdet,et al.  A Robust and Sensitive Metric for Quantifying Movement Smoothness , 2012, IEEE Transactions on Biomedical Engineering.

[18]  Emiliano Schena,et al.  Design and Feasibility Assessment of a Magnetic Resonance-Compatible Smart Textile Based on Fiber Bragg Grating Sensors for Respiratory Monitoring , 2016, IEEE Sensors Journal.

[19]  Emiliano Schena,et al.  Smart textile for respiratory monitoring and thoraco‐abdominal motion pattern evaluation , 2018, Journal of biophotonics.

[20]  Diane Podsiadlo,et al.  The Timed “Up & Go”: A Test of Basic Functional Mobility for Frail Elderly Persons , 1991, Journal of the American Geriatrics Society.

[21]  John-Stuart Brittain,et al.  Tremor stability index: a new tool for differential diagnosis in tremor syndromes , 2017, Brain : a journal of neurology.

[22]  S. Fahn Members of the UPDRS Development Committee. Unified Parkinson's Disease Rating Scale , 1987 .

[23]  F. Horak,et al.  iTUG, a Sensitive and Reliable Measure of Mobility , 2010, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[24]  LarsNyberg,et al.  Patient Falls in Stroke Rehabilitation , 1995 .

[25]  E. Katunina,et al.  [Epidemiology of Parkinson's disease]. , 2013, Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova.

[26]  J. D. Parkes,et al.  Fluctuations of disability in Parkinson's disease – clinical aspects , 1981 .

[27]  R M Pickering,et al.  A community-dwelling sample of people with Parkinson's disease: characteristics of fallers and non-fallers. , 2001, Age and ageing.

[28]  Domenico Formica,et al.  On the Orientation Error of IMU: Investigating Static and Dynamic Accuracy Targeting Human Motion , 2016, PloS one.

[29]  Kamiar Aminian,et al.  Ambulatory Monitoring of Physical Activities in Patients With Parkinson's Disease , 2007, IEEE Transactions on Biomedical Engineering.

[30]  Domenico Formica,et al.  Assessing bradykinesia in Parkinson's disease using gyroscope signals , 2017, 2017 International Conference on Rehabilitation Robotics (ICORR).

[31]  A. Lang,et al.  Parkinson's disease. First of two parts. , 1998, The New England journal of medicine.

[32]  Bijan Najafi,et al.  Falling risk evaluation in elderly using miniature gyroscope , 2000, 1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451).

[33]  Liu Chun-Lin,et al.  A Tutorial of the Wavelet Transform , 2010 .

[34]  G. Di Pino,et al.  Neurophysiological bases of tremors and accelerometric parameters analysis , 2012, 2012 4th IEEE RAS & EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob).

[35]  D. Formica,et al.  Smart Textile Based on Fiber Bragg Grating Sensors for Respiratory Monitoring: Design and Preliminary Trials , 2015, Biosensors.