Characterization, quantification, and replication of human sinus bone for surgery simulation phantoms

Abstract The requirement for artificial but realistic, tactile, anatomical models for surgical practice in medical simulation is increasingly evident and shows potential for greater efficiency and availability, and lower costs. Anatomically correct, detailed models with the physical surgical characteristics of real tissue, combined with the ability to reproduce one-off cases, would provide an invaluable tool in the development of surgery. This research work investigates the capture of geometrical and physical data from the human sinus to subsequently direct the production and optimization of such simulation phantoms. Micro-computed tomography analysis of the entire sinus was performed to characterize the sinus complex geometry. Following an extensive review, specialized mechanical testing apparatus and methods relevant to the surgical methods employed were designed and produced. This provided comparative analysis methods for both biological and artificial phantom materials and allowed the optimization of phantom materials with respect to the derived target values.

[1]  Joseph M. Wallace,et al.  The mechanical phenotype of biglycan-deficient mice is bone- and gender-specific. , 2006, Bone.

[2]  K. Leong,et al.  Rapid Prototyping: Principles and Applications (with Companion CD-ROM) , 2003 .

[3]  Ralf Westphal,et al.  Sensor-based force measurement during FESS for robot assisted surgery , 2007 .

[4]  Y. Toshev,et al.  MEDICAL RAPID PROTOTYPING APPLICATIONS AND METHODS , 2005 .

[5]  Yuehuei H. An,et al.  Mechanical testing of bone and the bone-implant interface , 1999 .

[6]  Francesco Cavani,et al.  The effect of pulsed electromagnetic fields on the osteointegration of hydroxyapatite implants in cancellous bone: a morphologic and microstructural in vivo study , 2002, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[7]  F Vanpoucke,et al.  High resolution micro-CT scanning as an innovatory tool for evaluation of the surgical positioning of cochlear implant electrodes , 2006, Acta oto-laryngologica.

[8]  Yan-Jun Zeng,et al.  Mechanical properties of nasal fascia and periosteum. , 2003, Clinical biomechanics.

[9]  K E Tanner,et al.  Fabrication of porous bioactive structures using the selective laser sintering technique , 2007, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[10]  S. Weiner,et al.  Microstructure-microhardness relations in parallel-fibered and lamellar bone. , 1996, Bone.

[11]  A A Friesem,et al.  Anisotropic Poisson's ratio and compression modulus of cortical bone determined by speckle interferometry. , 2007, Journal of biomechanics.

[12]  Chee Kai Chua,et al.  Rapid Prototyping:Principles and Applications , 2010 .

[13]  S. Cowin Bone mechanics handbook , 2001 .

[14]  P. Rüegsegger,et al.  A microtomographic system for the nondestructive evaluation of bone architecture , 2006, Calcified Tissue International.

[15]  S. Cowin,et al.  Bone Mechanics Handbook, 2nd Edition. - , 2003 .

[16]  A. Cuschieri,et al.  Development of force measurement system for clinical use in minimal access surgery , 2008, Surgical Endoscopy.