A global analysis of cross-talk in a mammalian cellular signalling network
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Madhusudan Natarajan | Rama Ranganathan | Robert C. Hsueh | R. Ranganathan | Madhusudan Natarajan | P. Sternweis | R. Hsueh | Keng-mean Lin | Paul C. Sternweis | Keng-Mean Lin
[1] K. Ozato,et al. IRF-8/Interferon (IFN) Consensus Sequence-binding Protein Is Involved in Toll-like Receptor (TLR) Signaling and Contributes to the Cross-talk between TLR and IFN-γ Signaling Pathways* , 2006, Journal of Biological Chemistry.
[2] C. Akdis,et al. Mechanisms of immune suppression by interleukin‐10 and transforming growth factor‐β: the role of T regulatory cells , 2006, Immunology.
[3] J. Lord,et al. Chemokine‐ and adhesion‐dependent survival of neutrophils after transmigration through cytokine‐stimulated endothelium , 2006, Journal of leukocyte biology.
[4] Richard A Flavell,et al. Transforming growth factor-beta regulation of immune responses. , 2006, Annual review of immunology.
[5] M. Caligiuri,et al. STAT‐1‐mediated repression of monocyte interleukin‐10 gene expression in vivo , 2006, European journal of immunology.
[6] G. Burnstock. Pathophysiology and Therapeutic Potential of Purinergic Signaling , 2006, Pharmacological Reviews.
[7] H. Yu,et al. GLUTAMINE INHIBITS LIPOPOLYSACCHARIDE-INDUCED CYTOPLASMIC PHOSPHOLIPASE A2 ACTIVATION AND PROTECTS AGAINST ENDOTOXIN SHOCK IN MOUSE , 2006, Shock.
[8] C. Brosnan,et al. Exacerbation of Experimental Autoimmune Encephalomyelitis in P2X7R−/− Mice: Evidence for Loss of Apoptotic Activity in Lymphocytes1 , 2006, The Journal of Immunology.
[9] M. Parmentier,et al. Extracellular adenine nucleotides inhibit the release of major monocyte recruiters by human monocyte‐derived dendritic cells , 2006, FEBS letters.
[10] J. Thurman,et al. The Central Role of the Alternative Complement Pathway in Human Disease1 , 2006, The Journal of Immunology.
[11] E. Stanley,et al. Colony-stimulating factor-1 in immunity and inflammation. , 2006, Current opinion in immunology.
[12] L. O’Neill,et al. How Toll-like receptors signal: what we know and what we don't know. , 2006, Current opinion in immunology.
[13] K. Isse,et al. Interferon γ accelerates NF-κB activation of biliary epithelial cells induced by Toll-like receptor and ligand interaction , 2006, Journal of Clinical Pathology.
[14] G. Mouchiroud,et al. The interferon‐inducible gene, Ifi204, is transcriptionally activated in response to M‐CSF, and its expression favors macrophage differentiation in myeloid progenitor cells , 2006, Journal of leukocyte biology.
[15] Paul B. Mann,et al. The Complex Mechanism of Antibody-Mediated Clearance of Bordetella from the Lungs Requires TLR41 , 2005, The Journal of Immunology.
[16] Rajagopal N. Aravalli,et al. Cutting Edge: TLR2-Mediated Proinflammatory Cytokine and Chemokine Production by Microglial Cells in Response to Herpes Simplex Virus1 , 2005, The Journal of Immunology.
[17] K. Heeg,et al. “Host Tissue Damage” Signal ATP Promotes Non-directional Migration and Negatively Regulates Toll-like Receptor Signaling in Human Monocytes* , 2005, Journal of Biological Chemistry.
[18] S. Jin,et al. Specific Role of Phosphodiesterase 4B in Lipopolysaccharide-Induced Signaling in Mouse Macrophages 1 , 2005, The Journal of Immunology.
[19] A. Dunne,et al. Adaptor usage and Toll‐like receptor signaling specificity , 2005, FEBS letters.
[20] T. Graeber,et al. TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells , 2005, Nature Medicine.
[21] F. Liew,et al. Negative regulation of Toll-like receptor-mediated immune responses , 2005, Nature Reviews Immunology.
[22] I. Haga,et al. The role of Toll-like receptors in the host response to viruses. , 2005, Molecular immunology.
[23] J. McHowat,et al. Phospholipase A2 inhibitors as potential anti-inflammatory agents. , 2005, Current pharmaceutical design.
[24] S. Hammer,et al. Overlapping Signaling Pathways of Sphingosine 1-Phosphate and TGF-β in the Murine Langerhans Cell Line XS521 , 2005, The Journal of Immunology.
[25] Joe G. N. Garcia,et al. In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insights. , 2005, Cellular signalling.
[26] K. Heeg,et al. Suppressor of Cytokine Signaling (SOCS) Proteins Indirectly Regulate Toll-like Receptor Signaling in Innate Immune Cells*♦ , 2004, Journal of Biological Chemistry.
[27] Chunli Feng,et al. Adenine Nucleotides Inhibit Cytokine Generation by Human Mast Cells through a Gs-Coupled Receptor1 , 2004, The Journal of Immunology.
[28] J. Hamilton,et al. Mini ReviewGM-CSF Biology , 2004, Growth factors.
[29] C. D. Krause,et al. Interferons, interferon‐like cytokines, and their receptors , 2004, Immunological reviews.
[30] A. Roberts,et al. Lysophosphatidic acid interacts with transforming growth factor-beta signaling to mediate keratinocyte growth arrest and chemotaxis. , 2004, The Journal of investigative dermatology.
[31] J. Boeynaems,et al. Involvement of multiple P2Y receptors and signaling pathways in the action of adenine nucleotides diphosphates on human monocyte‐derived dendritic cells , 2004, Journal of leukocyte biology.
[32] A. Roberts,et al. Involvement of Smad Signaling in Sphingosine 1-Phosphate-mediated Biological Responses of Keratinocytes* , 2004, Journal of Biological Chemistry.
[33] A. Ohta,et al. Cutting Edge: Physiologic Attenuation of Proinflammatory Transcription by the Gs Protein-Coupled A2A Adenosine Receptor In Vivo , 2004, The Journal of Immunology.
[34] Y. Kuroda,et al. Prostaglandin E2 receptors EP2 and EP4 are up‐regulated in peritoneal macrophages and joints of pristane‐treated mice and modulate TNF‐α and IL‐6 production , 2004, Journal of leukocyte biology.
[35] Takao Shimizu,et al. Absence of platelet-activating factor receptor protects mice from osteoporosis following ovariectomy. , 2004, The Journal of clinical investigation.
[36] Osamu Takeuchi,et al. The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection , 2004, The Journal of experimental medicine.
[37] J. Chun,et al. Lysophospholipid receptors: signaling and biology. , 2004, Annual review of biochemistry.
[38] H. Rabb,et al. Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury. , 2004, American journal of respiratory and critical care medicine.
[39] N. Gray,et al. Sphingosine 1-Phosphate (S1P) Receptor Subtypes S1P1 and S1P3, Respectively, Regulate Lymphocyte Recirculation and Heart Rate* , 2004, Journal of Biological Chemistry.
[40] H. Tilg,et al. Type I interferons and their therapeutic role in Th2-regulated inflammatory disorders , 2004, Expert opinion on biological therapy.
[41] M. Daha,et al. Mini‐review: A pivotal role for innate immunity in the clearance of apoptotic cells , 2004, European journal of immunology.
[42] J. Hamilton,et al. Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4. , 2004, American journal of physiology. Lung cellular and molecular physiology.
[43] M. Teixeira,et al. Sponge‐induced angiogenesis and inflammation in PAF receptor‐deficient mice (PAFR‐KO) , 2004, British journal of pharmacology.
[44] C. D. Krause,et al. Interleukin-10 and related cytokines and receptors. , 2004, Annual review of immunology.
[45] M. Netea,et al. Toll-Like Receptor 2 Suppresses Immunity against Candida albicans through Induction of IL-10 and Regulatory T Cells , 2004, The Journal of Immunology.
[46] F. Tremblay,et al. Sphingosine 1‐phosphate effect on endothelial cell PAF synthesis: Role in cellular migration , 2003, Journal of cellular biochemistry.
[47] M. Caligiuri,et al. The role of STAT1 in viral sensitization to LPS , 2003, Journal of endotoxin research.
[48] Paul J Hertzog,et al. The interferon in TLR signaling: more than just antiviral. , 2003, Trends in immunology.
[49] A. Lacy-Hulbert,et al. Apoptotic Cells and Innate Immune Stimuli Combine to Regulate Macrophage Cytokine Secretion 1 , 2003, The Journal of Immunology.
[50] T. Hartung,et al. Cyclic AMP increases endogenous granulocyte colony‐stimulating factor formation in monocytes and THP‐1 macrophages despite attenuated TNF‐α formation , 2003, European journal of immunology.
[51] Takao Shimizu,et al. Experimental Trypanosoma cruzi infection in platelet-activating factor receptor-deficient mice. , 2003, Microbes and infection.
[52] S. Akira,et al. Role of adapters in Toll-like receptor signalling. , 2003, Biochemical Society transactions.
[53] K. Heeg,et al. TLR-induced negative regulatory circuits: role of suppressor of cytokine signaling (SOCS) proteins in innate immunity. , 2003, Vaccine.
[54] G. Hatch,et al. Regulation of cytosolic phospholipase A2, cyclooxygenase-1 and -2 expression by PMA, TNFα, LPS and M-CSF in human monocytes and macrophages , 2003, Molecular and Cellular Biochemistry.
[55] N. Brot,et al. Opsonization of Apoptotic Cells and Its Effect on Macrophage and T Cell Immune Responses , 2003, Annals of the New York Academy of Sciences.
[56] Rolf Rossaint,et al. Activation of STAT3 by IL-6 and IL-10 in Primary Human Macrophages Is Differentially Modulated by Suppressor of Cytokine Signaling 3 1 , 2003, The Journal of Immunology.
[57] K. Heeg,et al. Synergistic and antagonistic interactions between LPS and superantigens , 2003, Journal of endotoxin research.
[58] S. Akira,et al. Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-β Promoter in the Toll-Like Receptor Signaling1 , 2002, The Journal of Immunology.
[59] Temple F. Smith,et al. Overview of the Alliance for Cellular Signaling , 2002, Nature.
[60] H. Kettenmann,et al. Interferon‐γ differentially modulates the release of cytokines and chemokines in lipopolysaccharide‐ and pneumococcal cell wall‐stimulated mouse microglia and macrophages , 2002 .
[61] R. Flavell,et al. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors , 2002, Nature.
[62] M. Fenton,et al. Toll-Like Receptor 4 and Toll-IL-1 Receptor Domain-Containing Adapter Protein (TIRAP)/Myeloid Differentiation Protein 88 Adapter-Like (Mal) Contribute to Maximal IL-6 Expression in Macrophages1 , 2002, The Journal of Immunology.
[63] A. Descoteaux,et al. Modulation of lipopolysaccharide‐induced NF‐IL6 activation by protein kinase C‐α in a mouse macrophage cell line , 2002, European journal of immunology.
[64] M. Bergmann,et al. Immunomodulatory effects of vasoactive catecholamines. , 2002, Wiener klinische Wochenschrift.
[65] P. Newburger,et al. Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils. , 2002, Blood.
[66] M. Takami,et al. Stimulation by Toll-Like Receptors Inhibits Osteoclast Differentiation1 , 2002, The Journal of Immunology.
[67] A. Nicolini,et al. MODULATION OF PGE2 AND TNFα BY NITRIC OXIDE IN RESTING AND LPS-ACTIVATED RAW 264.7 CELLS , 2002 .
[68] S. Taffet,et al. The proximal promoter region is essential for lipopolysaccharide induction and cyclic AMP inhibition of mouse tumor necrosis factor-alpha. , 2002, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[69] G. Zimmerman,et al. The platelet-activating factor signaling system and its regulators in syndromes of inflammation and thrombosis , 2002, Critical care medicine.
[70] J. J. Moreno,et al. Role of Ca(2+)-independent phospholipase A(2) and cyclooxygenase/lipoxygenase pathways in the nitric oxide production by murine macrophages stimulated by lipopolysaccharides. , 2002, Nitric oxide : biology and chemistry.
[71] A. Kolada,et al. Lipopolysaccharide-induced release of arachidonic acid and prostaglandins in liver macrophages: regulation by Group IV cytosolic phospholipase A2, but not by Group V and Group IIA secretory phospholipase A2. , 2002, Cellular signalling.
[72] Shizuo Akira,et al. Toll-like receptors as adjuvant receptors. , 2002, Biochimica et biophysica acta.
[73] S. Ullrich,et al. Platelet-activating Factor, a Molecular Sensor for Cellular Damage, Activates Systemic Immune Suppression , 2002, The Journal of experimental medicine.
[74] V. Sanders,et al. Norepinephrine and beta 2-adrenergic receptor stimulation regulate CD4+ T and B lymphocyte function in vitro and in vivo. , 2001, Pharmacological reviews.
[75] J. Berzofsky,et al. Mechanisms of cytokine synergy essential for vaccine protection against viral challenge. , 2001, International immunology.
[76] T. Ohmori,et al. Sphingosine 1-phosphate: synthesis and release. , 2001, Prostaglandins & other lipid mediators.
[77] Allan Randrup Thomsen,et al. Viral Infection Causes Rapid Sensitization to Lipopolysaccharide: Central Role of IFN-αβ1 , 2001, The Journal of Immunology.
[78] S. Akira,et al. Toll-like receptors and their signaling mechanism in innate immunity , 2001, Acta odontologica Scandinavica.
[79] S. Akira,et al. Synergy and Cross-Tolerance Between Toll-Like Receptor (TLR) 2- and TLR4-Mediated Signaling Pathways1 , 2000, The Journal of Immunology.
[80] J. Pugin,et al. β-Adrenergic agonists exert their “anti-inflammatory” effects in monocytic cells through the IκB/NF-κB pathway , 2000 .
[81] Judith R. Campbell,et al. Cytokines Enhance Opsonophagocytosis of Type III Group B Streptococcus , 2000, Journal of Perinatology.
[82] S. Vogel,et al. Inhibition of Lipopolysaccharide-Induced Signal Transduction in Endotoxin-Tolerized Mouse Macrophages: Dysregulation of Cytokine, Chemokine, and Toll-Like Receptor 2 and 4 Gene Expression1 , 2000, The Journal of Immunology.
[83] A S Slutsky,et al. Effect of adrenoreceptors on endotoxin-induced cytokines and lipid peroxidation in lung explants. , 1999, American journal of respiratory and critical care medicine.
[84] A. Sala,et al. Cyclooxygenase-2-dependent generation of 8-epiprostaglandin F2α by lipopolysaccharide-activated J774 macrophages , 1999, Inflammation Research.
[85] M. McCloskey,et al. Chemotaxis of rat mast cells toward adenine nucleotides. , 1999, Journal of immunology.
[86] Jianjun Gao,et al. Autocrine/Paracrine IFN-αβ Mediates the Lipopolysaccharide-Induced Activation of Transcription Factor Stat1α in Mouse Macrophages: Pivotal Role of Stat1α in Induction of the Inducible Nitric Oxide Synthase Gene , 1998, The Journal of Immunology.
[87] C. Caldarera,et al. ATP depletion inhibits glucocorticoid-induced thymocyte apoptosis. , 1997, Biochemical Journal.
[88] L. Rohrschneider,et al. Growth and differentiation signals regulated by the M‐CSF receptor , 1997, Molecular reproduction and development.
[89] L. Hang,et al. Immunoregulatory cytokines modify Escherichia coli induced uroepithelial cell IL-6 and IL-8 responses. , 1996, Cytokine.
[90] S. Leibler,et al. Kinetics of self-assembling microtubules: an "inverse problem" in biochemistry. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[91] J. Ihle. Cytokine receptor signalling , 1995, Nature.
[92] S. Lightman,et al. Nucleotides as Extracellular Signalling Molecules , 1995, Journal of neuroendocrinology.
[93] J. Gamble,et al. The role of granulocyte-macrophage and granulocyte colony-stimulating factors in neutrophil transendothelial migration: comparison with interleukin-8. , 1994, Experimental hematology.
[94] J. Mcghee,et al. Transforming growth factor-beta and IL-1 beta act in synergy to enhance IL-6 secretion by the intestinal epithelial cell line, IEC-6. , 1993, Journal of immunology.
[95] D. Riches,et al. Expression of interferon-beta during the triggering phase of macrophage cytocidal activation. Evidence for an autocrine/paracrine role in the regulation of this state. , 1991, The Journal of biological chemistry.
[96] S. Jacobsen,et al. Stimulation of granulopoiesis by transforming growth factor beta: synergy with granulocyte/macrophage-colony-stimulating factor. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[97] M. Feldmann,et al. Interleukin 4 induces interleukin 6 production by endothelial cells: Synergy with interferon‐γ , 1991, European journal of immunology.
[98] A. Goldbeter,et al. Latency correlates with period in a model for signal-induced Ca2+ oscillations based on Ca2(+)-induced Ca2+ release. , 1990, Cell regulation.
[99] A Goldbeter,et al. Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[100] J. Vilček,et al. IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice. , 1989, Journal of immunology.
[101] C. Baglioni,et al. Bacterial lipopolysaccharide and gamma interferon induce transcription of beta interferon mRNA and interferon secretion in murine macrophages , 1989, Journal of virology.
[102] K. Isse,et al. Interferon gamma accelerates NF-kappaB activation of biliary epithelial cells induced by Toll-like receptor and ligand interaction. , 2006, Journal of clinical pathology.
[103] B. Lakatoš,et al. ATP-induced apoptosis of thymocytes is mediated by activation of P2 X 7 receptor and involves de novo ceramide synthesis and mitochondria. , 2006, Biochimica et biophysica acta.
[104] J. Köhl,et al. Complement and Toll-like receptors: key regulators of adaptive immune responses. , 2006, Molecular immunology.
[105] R. Flavell,et al. TGFbeta-mediated immunoregulation. , 2006, Ernst Schering Research Foundation workshop.
[106] C. Akdis,et al. T regulatory cells in allergy. , 2006, Chemical immunology and allergy.
[107] Ching-Mei Hsu,et al. Different pathways leading to activation of extracellular signal-regulated kinase and p38 MAP kinase by formyl-methionyl-leucyl-phenylalanine or platelet activating factor in human neutrophils. , 2005, Journal of biomedical science.
[108] T. Kishimoto. Interleukin-6: from basic science to medicine--40 years in immunology. , 2005, Annual review of immunology.
[109] A. Nicolini,et al. Modulation of PGE(2) and TNFalpha by nitric oxide and LPS-activated RAW 264.7 cells. , 2002, Cytokine.
[110] G. Sen,et al. Viruses and interferons. , 2001, Annual review of microbiology.
[111] R. Coffman,et al. Interleukin-10 and the interleukin-10 receptor. , 2001, Annual review of immunology.
[112] S Rozen,et al. Primer3 on the WWW for general users and for biologist programmers. , 2000, Methods in molecular biology.
[113] S. Akira,et al. Critical roles of Toll-like receptors in host defense. , 2000, Critical reviews in immunology.
[114] S. Vogel,et al. Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharide-induced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene. , 1998, Journal of immunology.
[115] B. Cronstein. Adenosine, an endogenous anti-inflammatory agent. , 1994, Journal of applied physiology.
[116] R. Gilkey. An evaluation of the , 1982 .
[117] R. Mojena,et al. Hierarchical Grouping Methods and Stopping Rules: An Evaluation , 1977, Comput. J..
[118] Mechanistic insights , 2022 .